Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Sasha McClain"'
Autor:
Nicholas Turner, Cynthia Huang-Bartlett, Kevin Kalinsky, Massimo Cristofanilli, Giampaolo Bianchini, Stephen Chia, Hiroji Iwata, Wolfgang Janni, Cynthia X Ma, Erica L Mayer, Yeon Hee Park, Steven Fox, Xiaochun Liu, Sasha McClain, Francois-Clement Bidard
Publikováno v:
Future Oncology. 19:559-573
ESR1 mutation ( ESR1m) is a frequent cause of acquired resistance to aromatase inhibitor (AI) plus cyclin-dependent kinase 4 and 6 inhibitors (CDK4/6i), which is a first-line therapy for hormone-receptor-positive (HR+)/human epidermal growth factor r
Autor:
Sauzanne Khalilieh, Tamara D. Cabalu, Yuhsin Kuo, Sasha McClain, Larissa Wenning, Ilias Triantafyllou, Yang Liu, Daniel P. Dreyer, Rosa I. Sanchez, S. Aubrey Stoch, Marian Iwamoto, Ka Lai Yee, Kerry L. Fillgrove
Publikováno v:
The Journal of Clinical Pharmacology. 61:394-405
Doravirine, a novel nonnucleoside reverse transcriptase inhibitor for the treatment of human immunodeficiency virus 1 (HIV-1), is predominantly cleared by cytochrome P450 (CYP) 3A4 and metabolized to an oxidative metabolite (M9). Coadministration wit
Autor:
Tommy Fu, Ming Lu, Piyush Sheladia, Eric Liang, Srdan Verstovsek, Yifan Zhai, Cunlin Wang, Dajun Yang, Sasha McClain, Boyd Mudenda, Naveen Pemmaraju, Jiao Ji
Publikováno v:
Blood. 136:15-16
Background: Pelcitoclax (APG-1252), a novel dual inhibitor of Bcl-2/Bcl-xL, is active as monotherapy in patients with advanced solid tumors and well tolerated up to 240 mg twice weekly (NCT03387332). Preclinical data suggest that cells with Janus-ass
Publikováno v:
Journal of Virology. 83:7049-7061
Proteasomes are the major source of proteases responsible for the generation of peptides bound to major histocompatibility complex class I molecules. Antigens, adjuvants, and cytokines can modulate the composition and enzymatic activity of proteasome
Autor:
Peifang Sun, Sachin Mani, Stefan Fernandez, John Bisbing, Timothy Burgess, Monika Simmons, Dupeh R. Palmer, Sasha McClain, Wellington Sun, Vicky Gunther
Publikováno v:
Infection and Immunity. 75:1359-1363
The Escherichia coli maltose-binding protein (MBP) is used to increase the stability and solubility of proteins in bacterial protein expression systems and is increasingly being used to facilitate the production and delivery of subunit vaccines again
Publikováno v:
Vaccine. 27(49)
Liposomal lipid A is an effective adjuvant for the delivery of antigens and for the induction of both cellular and humoral immunity. In this study, we demonstrate that following the third immunization with HIV-1 Gag p24 encapsulated in liposomes cont
Autor:
Richard G. Jarman, Peifang Sun, Stephen B. Thomas, Robert V. Gibbons, Julia Lynch, Robert Putnak, Timothy Burgess, Edwin Kamau, Dupeh R. Palmer, Ratree Takhampunya, Sasha McClain, David A. Barvir, Chunlin Zhang
Publikováno v:
Virus research. 145(1)
Eighteen dengue viruses (DENVs) representing all four serotypes, isolated from pediatric patients at children's hospital, Queen Sirikit National Institute of Child Health, Bangkok, Thailand exhibiting a diverse spectrum of disease ranging from uncomp