Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Sasha J Rose"'
Publikováno v:
PLoS ONE, Vol 17, Iss 8, p e0272575 (2022)
PurposeNeutrophil serine proteases (NSPs) are implicated in numerous inflammatory diseases. Thus, a robust methodology to monitor and quantify NSPs is important to study disease progression and evaluate the effect of pharmacological interventions. A
Externí odkaz:
https://doaj.org/article/2a93b283d3564f1a9866e8426a8f046d
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0128772 (2015)
Mycobacterium avium subsp. hominissuis is an opportunistic pathogen that is associated with biofilm-related infections of the respiratory tract and is difficult to treat. In recent years, extracellular DNA (eDNA) has been found to be a major componen
Externí odkaz:
https://doaj.org/article/609bd132fae14879a1b1c7d0a135d8fd
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e108703 (2014)
Pulmonary infections caused by nontuberculous mycobacteria (NTM) are an increasing problem in individuals with chronic lung conditions and current therapies are lacking. We investigated the activity of liposomal amikacin for inhalation (LAI) against
Externí odkaz:
https://doaj.org/article/9273df733097429692c1e97096ccf691
Autor:
Donna M. Konicek, Adam J. Plaunt, Sachin Gharse, Sasha J. Rose, Arielle Dorfman, Amruta Sabnis, Thomas Baker, Helena Gauani, Donald Chun, Zhili Li, Walter R. Perkins, David Cipolla, Vladimir S. Malinin
Publikováno v:
Pharmaceutics, Vol 15, Iss 9, p 2250 (2023)
The increased prevalence of pulmonary methicillin-resistant Staphylococcus aureus (MRSA) infection in patients living with cystic fibrosis (CF) is concerning due to a correlation with reduced life expectancy and lack of available treatment options. R
Externí odkaz:
https://doaj.org/article/489479d94ae3433599532bcbf80b551d
Publikováno v:
International Journal of Microbiology, Vol 2019 (2019)
Bovine tuberculosis (bTB) is a highly transmissible infection and remains of great concern as a zoonosis. The worldwide incidence of bTB is in rise, creating potential reservoir and increased infection risk for humans and animals. In attempts to iden
Externí odkaz:
https://doaj.org/article/e3a13c6458664a08966077eab36a6fd9
Autor:
Adam J. Plaunt, Sasha J. Rose, Jeong Yeon Kang, Kuan-Ju Chen, Daniel LaSala, Ryan P. Heckler, Arielle Dorfman, Barrett T. Smith, Donald Chun, Veronica Viramontes, Antonio Macaluso, Zhili Li, Yuchen Zhou, Lilly Mark, Jessica Basso, Franziska G. Leifer, Michel R. Corboz, Richard W. Chapman, David Cipolla, Walter R. Perkins, Vladimir S. Malinin, Donna M. Konicek
Publikováno v:
Antimicrob Agents Chemother
Chronic pulmonary methicillin-resistant Staphylococcus aureus (MRSA) disease in cystic fibrosis (CF) has a high probability of recurrence following treatment with standard-of-care antibiotics and represents an area of unmet need associated with reduc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f7982c69e91dbbdd3bc2a38062e4560
https://europepmc.org/articles/PMC9664855/
https://europepmc.org/articles/PMC9664855/
Autor:
Sasha J. Rose, Luiz E. Bermudez
Publikováno v:
mBio, Vol 7, Iss 6 (2016)
ABSTRACT Extracellular DNA (eDNA) is an integral biofilm matrix component of numerous pathogens, including nontuberculous mycobacteria (NTM). Cell lysis is the source of eDNA in certain bacteria, but the source of eDNA remains unidentified for NTM, a
Externí odkaz:
https://doaj.org/article/3607d5e10d35408183ac624077421635
Publikováno v:
mBio, Vol 5, Iss 4 (2014)
ABSTRACT Inhibition of apoptotic death of macrophages by Mycobacterium tuberculosis represents an important mechanism of virulence that results in pathogen survival both in vitro and in vivo. To identify M. tuberculosis virulence determinants involve
Externí odkaz:
https://doaj.org/article/38a9caf78e4443d5bcf0f0a943f229c9
Autor:
David Cipolla, Jessica Basso, Donald Chun, Lilly Mark, Vladimir Malinin, Richard W. Chapman, Daniel LaSala, Sasha J. Rose, Barrett T Smith, Zhili Li, Michel R. Corboz, Ryan P Heckler, Arielle Dorfman, Adam J. Plaunt, Yuchen Zhou, Jeong Yeon Kang, Veronica Viramontes, Antonio Macaluso, Kuan-Ju Chen, Walter Perkins, Donna M. Konicek, Franziska Leifer
Publikováno v:
Antimicrobial Agents and Chemotherapy
Chronic pulmonary methicillin-resistant Staphylococcus aureus (MRSA) disease in cystic fibrosis (CF) has a high probability of recurrence following treatment with standard-of-care antibiotics and represents an area of unmet need associated with reduc
Autor:
Lia Danelishvili, Kylee L Carson, Rajoana Rojony, Luiz E. Bermudez, Sasha J. Rose, Amy L. Palmer
Publikováno v:
Virulence, Vol 9, Iss 1, Pp 1287-1300 (2018)
Virulence
Virulence
Mycobacterium avium subsp. hominissuis is an opportunistic intracellular pathogen associated with disease in patients either immunosuppression or chronic lung pathology. Once in the host, M. avium preferentially infects and replicates within the phag