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of 5
pro vyhledávání: '"Sasha Hobson"'
Autor:
Kathryn E. Sánchez, Shanya Jiang, Sharina Palencia Desai, Jeffery Thompson, Sasha Hobson, Gary A. Rosenberg, Kiran Bhaskar
Publikováno v:
STAR Protocols, Vol 5, Iss 1, Pp 102916- (2024)
Summary: Apoptosis-associated speck-like protein containing a c-terminal caspase activation and recruitment domain (ASC) specks are elevated in the cerebrospinal fluid (CSF) of Alzheimer’s disease and related dementias (AD/ADRDs) patients. Here, we
Externí odkaz:
https://doaj.org/article/cdb71a31e5af421cb405829c89c0a119
Autor:
Laura Hillmer, Erik Erhardt, Arvind Caprihan, John Adair, Janice Knoefel, Jillian Prestopnik, Jeffrey Thompson, Sasha Hobson, Gary Rosenberg
Publikováno v:
Cerebral Circulation - Cognition and Behavior, Vol 6, Iss , Pp 100312- (2024)
Introduction: The blood-brain barrier (BBB) is important in vascular cognitive impairment dementia (VCID) and Alzheimer's disease (AD). There are two methods uto measures BBB permeability: 1) the ratio of the concentration of albumin in blood to that
Externí odkaz:
https://doaj.org/article/65c7514099e240f2945b13d4797751b0
Autor:
Erik B. Erhardt, John C. Adair, Janice E. Knoefel, Arvind Caprihan, Jillian Prestopnik, Jeffrey Thompson, Sasha Hobson, David Siegel, Gary A. Rosenberg
Publikováno v:
Frontiers in Aging Neuroscience, Vol 13 (2021)
Dual pathology of Alzheimer's disease (AD) and vascular cognitive impairment and dementia (VCID) commonly are found together at autopsy, but mixed dementia (MX) is difficult to diagnose during life. Biological criteria to diagnose AD have been define
Externí odkaz:
https://doaj.org/article/638f96ebe2924ec1909fb2251359274e
Autor:
Limor Raz, Yi Yang, Jeffrey Thompson, Sasha Hobson, John Pesko, Shahriar Mobashery, Mayland Chang, Gary Rosenberg
Publikováno v:
PLoS ONE, Vol 13, Iss 12, p e0208357 (2018)
Vascular cognitive impairment dementia (VCID) is a major cause of cognitive loss in the elderly. Matrix metalloproteinases (MMPs) are a family of proteases involved in remodeling the extracellular matrix in development, injury and repair. Blood-brain
Externí odkaz:
https://doaj.org/article/3c2f02e33dea4c7da41c9fac3311f861
Autor:
Laura Hillmer, Erik B Erhardt, Arvind Caprihan, John C Adair, Janice E Knoefel, Jill Prestopnik, Jeffrey Thompson, Sasha Hobson, Gary A Rosenberg
Publikováno v:
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.
Blood-brain barrier (BBB) permeability can be measured by the ratio of albumin in cerebrospinal fluid (CSF) and blood and by dynamic contrast-enhanced MRI (DCEMRI). Albumin is a large molecule measured in CSF and blood to form the albumin index (Qalb