Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Sasha H, Shafikhani"'
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
Diabetes mellitus, commonly referred to as diabetes, is a group of metabolic disorders characterized by chronic elevation in blood glucose levels, resulting from inadequate insulin production, defective cellular response to extracellular insulin, and
Externí odkaz:
https://doaj.org/article/8ee36c64b18d459b8ca8373577775a1a
Autor:
Mohamed F. Mohamed, Kajal Gupta, Josef W. Goldufsky, Ruchi Roy, Lauren T. Callaghan, Dawn M. Wetzel, Timothy M. Kuzel, Jochen Reiser, Sasha H. Shafikhani
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Pseudomonas aeruginosa secretes the toxin ExoT, which is important for pathogenesis. Here, the authors show that ExoT inhibits NLRC4-dependent inflammatory responses during wound infection.
Externí odkaz:
https://doaj.org/article/2342fcd19c9a489d89c6717fe4338e53
Autor:
Mohamed F. Mohamed, Samer Al-Khudari, Puebla Cassini-Vieira, Amani Erra, Reem Bagabas, Thomas Houser, Kerstin Stenson, Mihir Bhayani, Michael J. Jelinek, Faraz Bishehsari, Timothy M. Kuzel, Sasha H. Shafikhani
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-8 (2022)
Abstract Recently, we described a phenomenon whereby apoptotic cells generate and release CrkI-containing microvesicles, which stimulate proliferation in surrounding cells upon contact to compensate for their own demise. We termed these microvesicles
Externí odkaz:
https://doaj.org/article/7fc7719325f246d987f6ab8b67d119df
Autor:
Ruchi Roy, Janet Zayas, Sunil K Singh, Kaylee Delgado, Stephen J Wood, Mohamed F Mohamed, Dulce M Frausto, Yasmeen A Albalawi, Thea P Price, Ricardo Estupinian, Eileena F Giurini, Timothy M Kuzel, Andrew Zloza, Jochen Reiser, Sasha H Shafikhani
Publikováno v:
eLife, Vol 11 (2022)
Infection is a major co-morbidity that contributes to impaired healing in diabetic wounds. Although impairments in diabetic neutrophils have been blamed for this co-morbidity, what causes these impairments and whether they can be overcome, remain lar
Externí odkaz:
https://doaj.org/article/1c02e2dfb8ec424ab1fb84f3147a9313
Publikováno v:
Cells, Vol 12, Iss 5, p 678 (2023)
Hypertrophic scarring (HTS) is an aberrant form of wound healing that is associated with excessive deposition of extracellular matrix and connective tissue at the site of injury. In this review article, we provide an overview of normal (acute) wound
Externí odkaz:
https://doaj.org/article/541a2df22e004d5fa653eb3b09398b73
Publikováno v:
Cells, Vol 12, Iss 1, p 195 (2023)
Pseudomonas aeruginosa is one of the most virulent opportunistic Gram-negative bacterial pathogens in humans. It causes many acute and chronic infections with morbidity and mortality rates as high as 40%. P. aeruginosa owes its pathogenic versatility
Externí odkaz:
https://doaj.org/article/d3042d1e81454b37801ebe86dbc04cf7
Publikováno v:
Cells, Vol 12, Iss 1, p 199 (2023)
Pseudomonas aeruginosa is an important Gram-negative opportunistic pathogen which causes many severe acute and chronic infections with high morbidity, and mortality rates as high as 40%. What makes P. aeruginosa a particularly challenging pathogen is
Externí odkaz:
https://doaj.org/article/036ed713f8b04fa5ac9ab19b557ba099
Autor:
Frederick J. Kohlhapp, Erica J. Huelsmann, Andrew T. Lacek, Jason M. Schenkel, Jevgenijs Lusciks, Joseph R. Broucek, Josef W. Goldufsky, Tasha Hughes, Janet P. Zayas, Hubert Dolubizno, Ryan T. Sowell, Regina Kühner, Sarah Burd, John C. Kubasiak, Arman Nabatiyan, Sh’Rae Marshall, Praveen K. Bommareddy, Shengguo Li, Jenna H. Newman, Claude E. Monken, Sasha H. Shafikhani, Amanda L. Marzo, Jose A. Guevara-Patino, Ahmed Lasfar, Paul G. Thomas, Edmund C. Lattime, Howard L. Kaufman, Andrew Zloza
Publikováno v:
Cell Reports, Vol 17, Iss 4, Pp 957-965 (2016)
In light of increased cancer prevalence and cancer-specific deaths in patients with infections, we investigated whether infections alter anti-tumor immune responses. We report that acute influenza infection of the lung promotes distal melanoma growth
Externí odkaz:
https://doaj.org/article/21c3de3968b44525b8ba15963e57feea
Autor:
Mohammad Bayat, Roohollah Ebrahimpour-Malekshah, Rouhallah Gazor, Seyed Kamran Ghoreishi, Abdollah Amini, Houssein Ahmadi, Robabeh Asadi, Atarodalsadat Mostafavinia, Fatemehalsadat Rezaei, Sufan Chien, Sasha H. Shafikhani, Latif Gachkar
Publikováno v:
Lasers in Medical Science. 37:1593-1604
Herein, we report the influence of administering different protocols of preconditioned diabetic adipose-derived mesenchymal stem cells (ADSs) with photobiomodulation in vitro, and photobiomodulation in vivo on the number of mast cells (MCs), their de
Publikováno v:
European cells & materials
Despite many preventive measures, including prophylactic antibiotics, periprosthetic joint infection (PJI) remains a devastating complication following arthroplasty, leading to pain, suffering, morbidity and substantial economic burden. Humans have a