Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Sascha Y. Kupke"'
Autor:
Daniel Rüdiger, Julita Piasecka, Jan Küchler, Carolina Pontes, Tanja Laske, Sascha Y. Kupke, Udo Reichl
Publikováno v:
iScience, Vol 27, Iss 4, Pp 109421- (2024)
Summary: Defective interfering particles (DIPs) are regarded as potent broad-spectrum antivirals. We developed a mathematical model that describes intracellular co-infection dynamics of influenza standard virus (STV) and “OP7”, a new type of infl
Externí odkaz:
https://doaj.org/article/f017adf2437f4bf8a8847f4a5920e2df
Autor:
Tanya Dogra, Lars Pelz, Julia D. Boehme, Jan Kuechler, Olivia Kershaw, Pavel Marichal-Gallardo, Maike Baelkner, Marc D. Hein, Achim D. Gruber, Dirk Benndorf, Yvonne Genzel, Dunja Bruder, Sascha Y. Kupke, Udo Reichl
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Influenza A virus (IAV) defective interfering particles (DIPs) are considered as new promising antiviral agents. Conventional DIPs (cDIPs) contain a deletion in the genome and can only replicate upon co-infection with infectious standard vir
Externí odkaz:
https://doaj.org/article/14074a084c1e479b80e20d113a9f8b14
Autor:
Marc D. Hein, Prerna Arora, Pavel Marichal-Gallardo, Michael Winkler, Yvonne Genzel, Stefan Pöhlmann, Klaus Schughart, Sascha Y. Kupke, Udo Reichl
Publikováno v:
BMC Biology, Vol 19, Iss 1, Pp 1-18 (2021)
Abstract Background Infections with influenza A virus (IAV) cause high morbidity and mortality in humans. Additional to vaccination, antiviral drugs are a treatment option. Besides FDA-approved drugs such as oseltamivir or zanamivir, virus-derived de
Externí odkaz:
https://doaj.org/article/ec222491feaa4fec951ed2e701ac97ce
Publikováno v:
PLoS Computational Biology, Vol 17, Iss 9, p e1009357 (2021)
Cell culture-derived defective interfering particles (DIPs) are considered for antiviral therapy due to their ability to inhibit influenza A virus (IAV) production. DIPs contain a large internal deletion in one of their eight viral RNAs (vRNAs) rende
Externí odkaz:
https://doaj.org/article/966bf3bc5b8e4f32b7114a566f90a7d9