Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Sascha Lange"'
Autor:
Henry Sawczyc, Takashi Tatsuta, Carl Öster, Spyridon Kosteletos, Sascha Lange, Claudia Bohg, Thomas Langer, Adam Lange
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-9 (2024)
Abstract Polymers can facilitate detergent-free extraction of membrane proteins into nanodiscs (e.g., SMALPs, DIBMALPs), incorporating both integral membrane proteins as well as co-extracted native membrane lipids. Lipid-only SMALPs and DIBMALPs have
Externí odkaz:
https://doaj.org/article/51fe6fabf26f4663ba7e2fcd3c4620ab
Publikováno v:
Industrial Artificial Intelligence, Vol 2, Iss 1, Pp 1-20 (2024)
Abstract The amount of labelled data in industrial use cases is limited because the annotation process is time-consuming and costly. As in research, self-supervised pretraining such as MAE resulted in training segmentation models with fewer labels, t
Externí odkaz:
https://doaj.org/article/31276db40a1e4255ae268aa32982a857
Publikováno v:
PLoS ONE, Vol 13, Iss 10, p e0204393 (2018)
A model for hematopoiesis is presented that explicitly includes the erythrocyte, granulocyte, and thrombocyte lineages and their common precursors. A small number of stem cells proliferate and differentiate through different compartments to produce t
Externí odkaz:
https://doaj.org/article/533339a6fef74582aa5e1c98d1559729
Autor:
Julia P Steringer, Sascha Lange, Sabína Čujová, Radek Šachl, Chetan Poojari, Fabio Lolicato, Oliver Beutel, Hans-Michael Müller, Sebastian Unger, Ünal Coskun, Alf Honigmann, Ilpo Vattulainen, Martin Hof, Christian Freund, Walter Nickel
Publikováno v:
eLife, Vol 6 (2017)
FGF2 is secreted from cells by an unconventional secretory pathway. This process is mediated by direct translocation across the plasma membrane. Here, we define the minimal molecular machinery required for FGF2 membrane translocation in a fully recon
Externí odkaz:
https://doaj.org/article/77e21a24ac8a4135a7f87861eb4cab35
Publikováno v:
ACS Physical Chemistry Au. 3:199-206
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5f246f9ac80104035cb7b70291793d64
https://doi.org/10.1021/acsphyschemau.2c00053
https://doi.org/10.1021/acsphyschemau.2c00053
Autor:
Adam Lange, Tillmann Utesch, Susanne Bischoff, Chaowei Shi, Claudia Bohg, Sascha Lange, Han Sun, Carl Öster
Publikováno v:
Chemical Science
Intramembrane proteolysis plays a fundamental role in many biological and pathological processes. Intramembrane proteases thus represent promising pharmacological targets, but few selective inhibitors have been identified. This is in contrast to thei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c56bed5965b92fbccd67fa177032a842
https://doi.org/10.1039/d1sc02146j
https://doi.org/10.1039/d1sc02146j
Direct Detection of Bound Ammonium Ions in the Selectivity Filter of Ion Channels by Solid-State NMR
Autor:
Carl Öster, Kumar Tekwani Movellan, Benjamin Goold, Kitty Hendriks, Sascha Lange, Stefan Becker, Bert L. de Groot, Wojciech Kopec, Loren B. Andreas, Adam Lange
Publikováno v:
Journal of the American Chemical Society
The flow of ions across cell membranes facilitated by ion channels is an important function for all living cells. Despite the huge amount of structural data provided by crystallography, elucidating the exact interactions between the selectivity filte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e9cdcde321a5b857224106be238d9a3
https://pubmed.ncbi.nlm.nih.gov/35200002
https://pubmed.ncbi.nlm.nih.gov/35200002
Publikováno v:
Biophysical Journal. 122:44a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::495d7cf0c372aa0c4f77a75c91a1566f
https://doi.org/10.1016/j.bpj.2022.11.449
https://doi.org/10.1016/j.bpj.2022.11.449
Autor:
Carl Öster, Veniamin Chevelkov, Claudia Bohg, Sascha Lange, Chaowei Shi, Adam Lange, Longmei Li
Publikováno v:
Journal of the American Chemical Society. 141:17314-17321
Rhomboid proteases are intramembrane proteases that hydrolyze substrate peptide bonds within the lipid bilayer and are important for a wide range of biological processes. The bacterial intramembrane protease GlpG is one of the model systems for struc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c95104ed1990b100871339cea224c26
https://doi.org/10.1021/jacs.9b08952
https://doi.org/10.1021/jacs.9b08952
Autor:
Dalila Durães, Sascha Lange, José Machado, Francisco Supino Marcondes, Paulo Novais, Flávio Arthur O. Santos
Publikováno v:
Highlights in Practical Applications of Agents, Multi-Agent Systems, and Social Good. The PAAMS Collection ISBN: 9783030857097
PAAMS (Workshops)
PAAMS (Workshops)
In recent years several applications, namely in surveillance, human-computer interaction and video recovery based on its content has studied the detection and recognition of violence [22]. The purpose of violence detection is to automatically and eff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::22a624aa409330a4d3a2b7d4966a1f4f
https://doi.org/10.1007/978-3-030-85710-3_6
https://doi.org/10.1007/978-3-030-85710-3_6
