Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Sascha K. Manier"'
Autor:
Michael E. G. Rosch, Jacqueline Rehner, Georges P. Schmartz, Sascha K. Manier, Uta Becker, Rolf Müller, Markus R. Meyer, Andreas Keller, Sören L. Becker, Verena Keller
Publikováno v:
One Health Outlook, Vol 6, Iss 1, Pp 1-13 (2024)
Abstract Background Different production systems of livestock animals influence various factors, including the gut microbiota. Methods We investigated whether changing the conditions from barns to free-range chicken farming impacts the microbiome ove
Externí odkaz:
https://doaj.org/article/9da3b84b89f543c6bbf6842b015fe7f1
Publikováno v:
Metabolites, Vol 14, Iss 6, p 342 (2024)
With a rising demand of cocaine over the last years, it is likely that unregulated new psychoactive substances with similar effects such as indatraline ((1R,3S)-3-(3,4-dichlorophenyl)-N-methyl-2,3-dihydro-1H-inden-1-amine) and troparil (Methyl (1R,2S
Externí odkaz:
https://doaj.org/article/df3464c68c3f4f8aaa956f73b0273292
Autor:
Philip Schippers, Sari Rasheed, Yu Mi Park, Timo Risch, Lea Wagmann, Selina Hemmer, Sascha K. Manier, Rolf Müller, Jennifer Herrmann, Markus R. Meyer
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract Sample preparation in untargeted metabolomics should allow reproducible extractions of as many molecules as possible. Thus, optimizing sample preparation is crucial. This study compared six different extraction procedures to find the most su
Externí odkaz:
https://doaj.org/article/b9392f1535d74728bfcbeb961ebba3ba
Publikováno v:
Metabolites, Vol 11, Iss 1, p 3 (2020)
Synthetic cathinones belong to the most often seized new psychoactive substances on an international level. This study investigated the toxicometabolomics, particularly the in vitro metabolism of 2-(methylamino)-1-(4-methylphenyl)-1-pentanone (4-MPD)
Externí odkaz:
https://doaj.org/article/a7397497257542ecb0e69dbe62a93daa
Autor:
Selina Hemmer, Sascha K. Manier, Svenja Fischmann, Folker Westphal, Lea Wagmann, Markus R. Meyer
Publikováno v:
Metabolites, Vol 10, Iss 11, p 432 (2020)
The authors wish to make the following comment to this paper [...]
Externí odkaz:
https://doaj.org/article/e17d28f4866c4c71b665805637e406ac
Autor:
Selina Hemmer, Sascha K. Manier, Svenja Fischmann, Folker Westphal, Lea Wagmann, Markus R. Meyer
Publikováno v:
Metabolites, Vol 10, Iss 9, p 378 (2020)
The evaluation of liquid chromatography high-resolution mass spectrometry (LC-HRMS) raw data is a crucial step in untargeted metabolomics studies to minimize false positive findings. A variety of commercial or open source software solutions are avail
Externí odkaz:
https://doaj.org/article/a0a5654f96314fa98c6424294c47b2ac
Publikováno v:
Drug Testing and Analysis. 13:1440-1444
Numerous case reports of intoxications with nutmeg seeds (Myristica fragrans, Houtt.) can be found in literature often following their abuse, as psychotropic effects were described after ingestions of large doses. The successful detection of the main
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de0fec69bb581d9ecfb5dc28b5f01152
https://doi.org/10.1002/dta.3027
https://doi.org/10.1002/dta.3027
Autor:
Christina Felske, Lea Wagmann, Sascha K. Manier, Matthias J Richter, Niels Eckstein, Tanja M. Gampfer, Markus R. Meyer
Publikováno v:
Journal of Analytical Toxicology. 45:1014-1027
Flubromazolam is widely known as highly potent designer benzodiazepine (DBZD). Recently, the two flubromazolam-derived new psychoactive substances (NPS) clobromazolam and bromazolam appeared on the drugs of abuse market. Since no information concerni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5290fb7415fb2a8e7cd3e02b3a2d52b
https://doi.org/10.1093/jat/bkaa161
https://doi.org/10.1093/jat/bkaa161
Publikováno v:
Archives of Toxicology
Toxicometabolomics, essentially applying metabolomics to toxicology of endogenous compounds such as drugs of abuse or new psychoactive substances (NPS), can be investigated by using different in vitro models and dedicated metabolomics techniques to e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::454e6c1b64f6f6f126ce33f2db0cf656
http://europepmc.org/articles/PMC7303098
http://europepmc.org/articles/PMC7303098
Publikováno v:
Journal of Analytical Toxicology. 44:156-162
The distribution of so-called new psychoactive substances (NPS) as substitute for common drug of abuse was steadily increasing in the last years, but knowledge about their toxicodynamic and toxicokinetic properties is lacking. However, a comprehensiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf5e27faf9cfc19f7ae94781e12766ae
https://doi.org/10.1093/jat/bkz052
https://doi.org/10.1093/jat/bkz052