Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Sascha Heinrich"'
Autor:
Leonie Sagurna, Sascha Heinrich, Lara-Sophie Kaufmann, Christian Rückert-Reed, Tobias Busche, Alexander Wolf, Jan Eickhoff, Bert Klebl, Jörn Kalinowski, Julia E. Bandow
Publikováno v:
Antibiotics, Vol 12, Iss 7, p 1116 (2023)
Bacteria of the genus Streptomyces produce various specialized metabolites. Single biosynthetic gene clusters (BGCs) can give rise to different products that can vary in terms of their biological activities. For example, for alnumycin and the shunt p
Externí odkaz:
https://doaj.org/article/d75d62b0f362495da387306443d4ba5d
Autor:
Bandow, Leonie Sagurna, Sascha Heinrich, Lara-Sophie Kaufmann, Christian Rückert-Reed, Tobias Busche, Alexander Wolf, Jan Eickhoff, Bert Klebl, Jörn Kalinowski, Julia E.
Publikováno v:
Antibiotics; Volume 12; Issue 7; Pages: 1116
Bacteria of the genus Streptomyces produce various specialized metabolites. Single biosynthetic gene clusters (BGCs) can give rise to different products that can vary in terms of their biological activities. For example, for alnumycin and the shunt p
Publikováno v:
Chemistry – A European Journal. 28
Recently, chalcogen bonding has been investigated in more detail in organocatalysis and the scope of activated functionalities continues to increase. Herein, the activation of imines in a Povarov [4+2] cycloaddition reaction with bidentate cationic c
Publikováno v:
Chemical Communications. 56:10926-10929
We report the application of VCD spectroscopy for the characterization of clarithromycin and erythromycin. We show that the VCD spectra of these large macrolides are distinctly different and that spectra calculations reproduce the experimentally obse
Publikováno v:
ChemBioChem. 23
The targeted manipulation of polyketide synthases has in recent years led to numerous new-to-nature polyketides. For type I polyketide synthases the response of post-polyketide synthases (PKS) processing enzymes onto the most frequently polyketide ba
Autor:
Anat Bashan, Frank Schulz, Johannes Zuegg, Niclas Pryk, Ada Yonath, Walter Thiel, Donna Matzov, Pandian Sokkar, Julia E. Bandow, Pascal Dietze, Elsa Sanchez-Garcia, Sascha Heinrich, David Möller, Gerhard König, Giuseppe Cimicata
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Due to the development of resistance against commonly used antibiotics, new derivatives that avoid resistance mechanisms need to be developed. To address this problem, a rational prioritization strategy is outlined for macrolide antibiot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7be7d83984e8b59ac582e20b854f5675
https://www.ncbi.nlm.nih.gov/pubmed/34750269
https://www.ncbi.nlm.nih.gov/pubmed/34750269
Autor:
David Möller, Frank Schulz, Susanna Kushnir, Sascha Heinrich, A. Ismail-Ali, Kyra R.M. Koopmans, F. Calo, Marius Grote, B. Diehl
Publikováno v:
Letters in applied microbiology. 67(3)
Streptomyces cinnamonensis A495 is a variant of the monensin producer which instead of the native polyether antibiotic gives rise to antibiotic and anti-tumour shunt-product premonensin. Through the supplementation of the fermentation medium with sui
Publikováno v:
MEGAFLOW-Numerical Flow Simulation for Aircraft Design ISBN: 9783540243830
The accuracy of the DLR structured and unstructured computational fluid dynamics (CFD) codes in predicting aircraft forces and moments on several configurations at low and high Mach and Reynolds numbers is investigated. Using a combination of a high
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5016a8036383e5f50ed2b54f4548bac
https://doi.org/10.1007/3-540-32382-1_10
https://doi.org/10.1007/3-540-32382-1_10