Zobrazeno 1 - 10 of 23 pro vyhledávání: '"Sascha Gross-Hardt"'
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Akademický článek
Optimizing cerebral perfusion and hemodynamics during cardiopulmonary bypass through cannula design combining in silico, in vitro and in vivo input
Autor: Kristin Hugenroth, Ralf Borchardt, Philine Ritter, Sascha Groß-Hardt, Bart Meyns, Tom Verbelen, Ulrich Steinseifer, Tim A. S. Kaufmann, Ulrich M. Engelmann
Publikováno v: Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Cardiopulmonary bypass (CPB) is a standard technique for cardiac surgery, but comes with the risk of severe neurological complications (e.g. stroke) caused by embolisms and/or reduced cerebral perfusion. We report on an aortic cannula protot
Externí odkaz: https://doaj.org/article/bfcccda03dbb4c2c899750442f7295d2
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2
Akademický článek
Low-flow assessment of current ECMO/ECCO2R rotary blood pumps and the potential effect on hemocompatibility
Autor: Sascha Gross-Hardt, Felix Hesselmann, Jutta Arens, Ulrich Steinseifer, Leen Vercaemst, Wolfram Windisch, Daniel Brodie, Christian Karagiannidis
Publikováno v: Critical Care, Vol 23, Iss 1, Pp 1-9 (2019)
Abstract Background Extracorporeal carbon dioxide removal (ECCO2R) uses an extracorporeal circuit to directly remove carbon dioxide from the blood either in lieu of mechanical ventilation or in combination with it. While the potential benefits of the
Externí odkaz: https://doaj.org/article/07000be0108140f6a544418ddaec05ae
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3
In-vitro performance of a single-chambered total artificial heart in a Fontan circulation
Autor: Ulrich Steinseifer, Stephan Hildebrand, Sebastian V. Jansen, Sascha Groß-Hardt, Thomas Schmitz-Rode
Publikováno v: Journal of artificial organs 25(1), 1-8 (2022). doi:10.1007/s10047-021-01273-5
Journal of artificial organs 25(1), 1-8 (2022). doi:10.1007/s10047-021-01273-5
Published by Springer, Tokyo
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dd4ac9fc27b0c388fbc176096dad9dd
https://publications.rwth-aachen.de/record/844315
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4
An Accelerated Thrombosis Model for Computational Fluid Dynamics Simulations in Rotary Blood Pumps
Autor: Ulrich Steinseifer, Christopher Blum, Sascha Groß-Hardt, Michael Neidlin
Publikováno v: Cardiovascular engineering and technology : CVET 13(4), 638-649 (2022). doi:10.1007/s13239-021-00606-y
Cardiovascular engineering and technology : CVET 13(4), 638-649 (2022). doi:10.1007/s13239-021-00606-y
Published by Springer, New York, NY
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9400823cdbf89f52973610129d90bc47
https://pubmed.ncbi.nlm.nih.gov/35031981
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5
Optimizing cerebral perfusion and hemodynamics during cardiopulmonary bypass through cannula design combining in silico, in vitro and in vivo input
Autor: Bart Meyns, Ulrich M. Engelmann, Tom Verbelen, Kristin Hugenroth, Ralf Borchardt, Ulrich Steinseifer, Philine Ritter, Sascha Groß-Hardt, Tim A.S. Kaufmann
Publikováno v: Scientific Reports
Scientific reports 11(1), 16800 (2021). doi:10.1038/s41598-021-96397-2
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Scientific reports 11(1), 16800 (2021). doi:10.1038/s41598-021-96397-2
Published by Macmillan Publishers Limited, part of Springer Nature, [London]
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cdec37c3c970544e4cc7be22f9357fa
https://doi.org/10.1038/s41598-021-96397-2
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6
Intraventricular Flow Simulations in Singular Right Ventricles Reveal Deteriorated Washout and Low Vortex Formation
Autor: Sascha Groß-Hardt, Michael Neidlin, Christian Winkler, Katharina Linden, Anna Grünwald, Jana Korte, Ulrike Herberg, Nadja Wilmanns, Ulrich Steinseifer
Publikováno v: Cardiovascular engineering and technology. 13(3)
Purpose Patients with a functionally univentricular heart represent one of the most common severe cardiac lesions with a prevalence of 3 per 10,000 live births. Hemodynamics of the singular ventricle is a major research topic in cardiology and there
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::649e9f8404763e734e283e3e7b2b6462
https://pubmed.ncbi.nlm.nih.gov/34850371
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7
How Computational Modeling can Help to Predict Gas Transfer in Artificial Lungs Early in the Design Process
Autor: Jutta Arens, Peter C. Schlanstein, Thomas Schmitz-Rode, Andreas Kaesler, Ulrich Steinseifer, Georg Wagner, Sascha Groß-Hardt, Marius Rosen
Publikováno v: ASAIO Journal, 66(6), 683-690. Lippincot, Williams & Wilkins
Wearable extracorporeal membrane oxygenation (ECMO) circuits may soon become a viable alternative to conventional ECMO treatment. Common device-induced complications, however, such as blood trauma and oxygenator thrombosis, must first be addressed to
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c584fc50a34db1ee286dcd6083f81233
https://doi.org/10.1097/mat.0000000000001098
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8
Crucial Aspects for Using Computational Fluid Dynamics as a Predictive Evaluation Tool for Blood Pumps
Autor: Simon J. Sonntag, Ulrich Steinseifer, Sascha Gross-Hardt, Tim A.S. Kaufmann, Fiete Boehning, Thomas Schmitz-Rode
Publikováno v: ASAIO Journal. 65:864-873
The suitability of computational fluid dynamics (CFD) as a regulatory tool for safety assessment of medical devices is still limited: A lack of standardized validation and evaluation methods impairs the quantitative comparability and reliability of s
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04f59fc643456402f7dfffe13181657a
https://doi.org/10.1097/mat.0000000000001023
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9
An energy-dissipation-based power-law formulation for estimating hemolysis
Autor: Sascha Groß-Hardt, Fiete Boehning, Po-Lin Hsu, Peng Wu
Publikováno v: Biomechanics and Modeling in Mechanobiology. 19:591-602
Hemolysis is a major concern in blood-circulating devices, which arises due to non-physiological stresses on red blood cells from ambient flow environment or moving mechanical structures. Computational fluid dynamics (CFD) and empirical hemolysis pre
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02688e857299ed4d79bf6a9f54a6e214
https://doi.org/10.1007/s10237-019-01232-3
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10
Hemolysis at low blood flow rates: in-vitro and in-silico evaluation of a centrifugal blood pump
Autor: Ulrich Steinseifer, Johanna C. Clauser, Daniel Brodie, Christian Karagiannidis, Sascha Groß-Hardt, Malte Schöps, Thomas Schmitz-Rode
Publikováno v: Journal of Translational Medicine
Journal of Translational Medicine, Vol 19, Iss 1, Pp 1-10 (2021)
Journal of translational medicine 19(1), 2 (2021). doi:10.1186/s12967-020-02599-z
Journal of translational medicine 19(1), 2 (2021). doi:10.1186/s12967-020-02599-z
Published by BioMed Central, London
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb2ff2ae0c7ff82df615639fb82fb082
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