Zobrazeno 1 - 10
of 95 954
pro vyhledávání: '"Sascha"'
Autor:
Sascha Keller, Ulrich Kunz, Ulrike Schmid, Jack Beusmans, Martin Büchert, Min He, Girish Jayadeva, Christophe Le Tourneau, Doreen Luedtke, Heiko G. Niessen, Zohra Oum’hamed, Sina Pleiner, Xiaoning Wang, Ralph Graeser
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-18 (2024)
Abstract Background BI 836880 is a humanized bispecific nanobody® that binds to and blocks vascular endothelial growth factor (VEGF) and angiopoietin-2 (Ang-2). A comprehensive biomarker and modeling approach is presented here that supported dose fi
Externí odkaz:
https://doaj.org/article/e16d3e8186014e00ab772fd03b57d4cc
Autor:
Maxim Noeraparast, Katarina Krajina, Renate Pichler, Dora Niedersüß‐Beke, Shahrokh F Shariat, Viktor Grünwald, Sascha Ahyai, Martin Pichler
Publikováno v:
Cancer Communications, Vol 44, Iss 10, Pp 1189-1208 (2024)
Abstract In this review, we revisit the pivotal role of fibroblast growth factor receptor 3 (FGFR3) in bladder cancer (BLCA), underscoring its prevalence in both non‐muscle‐invasive and muscle‐invasive forms of the disease. FGFR3 mutations in u
Externí odkaz:
https://doaj.org/article/9e3eb5c1f9b94eb79fa47e4b178e90be
Autor:
Bettina Wenzel, Julian Winkler, Sascha M. Kirchner, Stephan Martin Junge, Pedro Mendonça, Fátima Alves, Hella Kehlenbeck
Publikováno v:
Agricultural and Food Economics, Vol 12, Iss 1, Pp 1-23 (2024)
Abstract Under the EU’s new “Farm to Fork” strategy, crop production systems should rapidly become more environmentally friendly. In particular, by adopting agroecological measures that support functional biodiversity and improve ecosystem serv
Externí odkaz:
https://doaj.org/article/c31eb3b2e3cb4e3aa8fc041ef73c6f51
Publikováno v:
Humanities & Social Sciences Communications, Vol 11, Iss 1, Pp 1-10 (2024)
Abstract Traditionally, language learners have relied on dictionaries when trying to read or write in a foreign language. However, new LLM-based chatbots may offer an alternative to traditional dictionaries as lexical tools. This study assesses the e
Externí odkaz:
https://doaj.org/article/8c465c70ed2c474490d62038574ae990
Publikováno v:
Humanities & Social Sciences Communications, Vol 11, Iss 1, Pp 1-13 (2024)
Abstract Research on gender and language is tightly knitted to social debates on gender equality and non-discriminatory language use. Psycholinguistic scholars have made significant contributions in this field. However, corpus-based studies that inve
Externí odkaz:
https://doaj.org/article/e2e50fd931354017b2bf0fbfeb8d075b
Autor:
Vincent Saint-Martin, Vanaique Guillory, Mélanie Chollot, Isabelle Fleurot, Emmanuel Kut, Ferdinand Roesch, Ignacio Caballero, Emmanuelle Helloin, Emilie Chambellon, Brian Ferguson, Philippe Velge, Florent Kempf, Sascha Trapp, Rodrigo Guabiraba
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-17 (2024)
Abstract The gut microbiota exerts profound influence on poultry immunity and metabolism through mechanisms that yet need to be elucidated. Here we used conventional and germ-free chickens to explore the influence of the gut microbiota on transcripto
Externí odkaz:
https://doaj.org/article/1d3f606ae25747978fd8bb0ea64e0fd3
Truncated mini LRP1 transports cargo from luminal to basolateral side across the blood brain barrier
Autor:
Laura Fritzen, Katharina Wienken, Lelia Wagner, Magdalena Kurtyka, Katharina Vogel, Jakob Körbelin, Sascha Weggen, Gert Fricker, Claus U. Pietrzik
Publikováno v:
Fluids and Barriers of the CNS, Vol 21, Iss 1, Pp 1-23 (2024)
Abstract Background The most crucial area to focus on when thinking of novel pathways for drug delivery into the CNS is the blood brain barrier (BBB). A number of nanoparticulate formulations have been shown in earlier research to target receptors at
Externí odkaz:
https://doaj.org/article/6959b746fc7b4f43abec3dada8978c0c
Publikováno v:
Fertility & Reproduction, Vol 06, Iss 03, Pp 112-116 (2024)
Background: In vitro fertilization (IVF) is the most widely applied fertility treatment. While the indication for IVF is not disputed in couples where natural conception chances are close to zero (blocked fallopian tubes or severe male infertility),
Externí odkaz:
https://doaj.org/article/9b214c4e69ce470da5e48e47a853c2d5
Autor:
Felix Karl-Ludwig Klingebiel, Kenichi Sawauchi, Anne Mittlmeier, Yannik Kalbas, Till Berk, Sascha Halvachizadeh, Michel Teuben, Valentin Neuhaus, Cyril Mauffrey, Hans-Christoph Pape, Roman Pfeifer
Publikováno v:
Patient Safety in Surgery, Vol 18, Iss 1, Pp 1-11 (2024)
Abstract Background The management of hemodynamically unstable pelvic ring injuries necessitates surgical intervention, often involving procedures such as external fixation and percutaneous screw placement. Given the infrequent performance of these p
Externí odkaz:
https://doaj.org/article/5be756810ef141ef87c9843a1a9e6cb2
Autor:
Julius Michael Wolfgart, Lea Cathrine Grötzner, Sascha Hemayatkar-Fink, Maik Schwitalle, Florian Christof Bonnaire, Martina Feierabend, Marina Danalache, Ulf Krister Hofmann
Publikováno v:
Journal of Orthopaedic Translation, Vol 48, Iss , Pp 232-243 (2024)
Background: In healthy articular cartilage, chondrocytes are found along arcades of collagen fibers as Single Strings. With onset of cartilage degeneration this pattern changes to Double Strings. In the course of osteoarthritis Small Clusters, and fi
Externí odkaz:
https://doaj.org/article/fb59ad23a07d4a80923f034b82799129