Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Sasank Sakhamuri"'
Autor:
Shalini Chopra, Kai Trepka, Sasank Sakhamuri, Alberto Carretero-González, Jun Zhu, Emily Egusa, Jie Zhou, Kevin Leung, Ning Zhao, Nima Hooshdaran, Felix Y. Feng, James A. Wells, Jonathan Chou, Michael J. Evans
Publikováno v:
Clinical Cancer Research. 29:1232-1242
Purpose: Despite recent approvals for checkpoint inhibitors and antibody–drug conjugates targeting NECTIN4 or TROP2, metastatic bladder cancer remains incurable and new treatment strategies are urgently needed. CUB domain–containing protein 1 (CD
Autor:
Alexandre M. Sorlin, Marina López-Álvarez, Sarah J. Rabbitt, Aryn A. Alanizi, Rebecca Shuere, Kondapa Naidu Bobba, Joseph Blecha, Sasank Sakhamuri, Michael J. Evans, Kenneth W. Bayles, Robert R. Flavell, Oren S. Rosenberg, Renuka Sriram, Tom Desmet, Bernd Nidetzky, Joanne Engel, Michael A. Ohliger, James S. Fraser, David M. Wilson
Publikováno v:
bioRxiv
Chemoenzymatic techniques have been applied extensively to pharmaceutical development, most effectively when routine synthetic methods fail. The regioselective and stereoselective construction of structurally complex glycans is an elegant application
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2aa23958f78334a4d79133ac7f66243f
https://europepmc.org/articles/PMC10245702/
https://europepmc.org/articles/PMC10245702/
Autor:
Michael J. Evans, Jonathan Chou, James A. Wells, Felix Y. Feng, Nima Hooshdaran, Ning Zhao, Kevin Leung, Jie Zhou, Emily Egusa, Jun Zhu, Alberto Carretero-González, Sasank Sakhamuri, Kai Trepka, Shalini Chopra
Purpose:Despite recent approvals for checkpoint inhibitors and antibody–drug conjugates targeting NECTIN4 or TROP2, metastatic bladder cancer remains incurable and new treatment strategies are urgently needed. CUB domain–containing protein 1 (CDC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4db1177f1551e4aefa0dabda0ae25ee3
https://doi.org/10.1158/1078-0432.c.6533116
https://doi.org/10.1158/1078-0432.c.6533116
Autor:
Michael J. Evans, Jonathan Chou, James A. Wells, Felix Y. Feng, Nima Hooshdaran, Ning Zhao, Kevin Leung, Jie Zhou, Emily Egusa, Jun Zhu, Alberto Carretero-González, Sasank Sakhamuri, Kai Trepka, Shalini Chopra
CDCP1 mRNA is not correlated NECTIN4 or TROP2 mRNA, related to Figure 2C. Spearman correlation analyses were performed between CDCP1 and NECTIN4 or TROP2 for the Seiler, Sjodahl 2017, and Sjodahl 2012 datasets, with p values and correlation coefficie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2338289ccb4af9f0a384645c00056ca4
https://doi.org/10.1158/1078-0432.22495104.v1
https://doi.org/10.1158/1078-0432.22495104.v1
Autor:
Michael J. Evans, Jonathan Chou, James A. Wells, Felix Y. Feng, Nima Hooshdaran, Ning Zhao, Kevin Leung, Jie Zhou, Emily Egusa, Jun Zhu, Alberto Carretero-González, Sasank Sakhamuri, Kai Trepka, Shalini Chopra
CDCP1 mRNA expression by site of biopsy, from the IMvigor210 dataset. p = 0.075 by Kruskal-Wallis test, n=348 samples
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a8b78946b641458716da3154cb351ca
https://doi.org/10.1158/1078-0432.22495113
https://doi.org/10.1158/1078-0432.22495113
Autor:
Michael J. Evans, Jonathan Chou, James A. Wells, Felix Y. Feng, Nima Hooshdaran, Ning Zhao, Kevin Leung, Jie Zhou, Emily Egusa, Jun Zhu, Alberto Carretero-González, Sasank Sakhamuri, Kai Trepka, Shalini Chopra
CDCP1 mRNA expression is not associated with overall survival. Kaplan–Meier survival analyses were performed on quartiles of CDCP1 mRNA expression with overall survival as the endpoint. p > 0.05 in both public datasets for which overall survival da
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6900e0ac8e2d1ccccfc3795c78d1d231
https://doi.org/10.1158/1078-0432.22490209.v1
https://doi.org/10.1158/1078-0432.22490209.v1
Autor:
Michael J. Evans, Jonathan Chou, James A. Wells, Felix Y. Feng, Nima Hooshdaran, Ning Zhao, Kevin Leung, Jie Zhou, Emily Egusa, Jun Zhu, Alberto Carretero-González, Sasank Sakhamuri, Kai Trepka, Shalini Chopra
A plot showing the mean tumor volume for the vehicle and treated arms from the antitumor assessment study in mice bearing UMUC3 xenografts. The differences in mean between treatment arms was found to be significant (P < 0.001) using an unpaired, two
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f9d00329695ac259f63d98f6654f146
https://doi.org/10.1158/1078-0432.22490200.v1
https://doi.org/10.1158/1078-0432.22490200.v1
Autor:
Michael J. Evans, Jonathan Chou, James A. Wells, Felix Y. Feng, Nima Hooshdaran, Ning Zhao, Kevin Leung, Jie Zhou, Emily Egusa, Jun Zhu, Alberto Carretero-González, Sasank Sakhamuri, Kai Trepka, Shalini Chopra
A summary of the data from saturation binding assays used to calculate Bmax and receptor number per cell for bladder cancer cell lines. The data are representative of two independent assays. Data are reported as mean ± standard deviation.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bbf5fa69c6894bd134fccd542fc5726
https://doi.org/10.1158/1078-0432.22490206
https://doi.org/10.1158/1078-0432.22490206
Autor:
Michael J. Evans, Jonathan Chou, James A. Wells, Felix Y. Feng, Nima Hooshdaran, Ning Zhao, Kevin Leung, Jie Zhou, Emily Egusa, Jun Zhu, Alberto Carretero-González, Sasank Sakhamuri, Kai Trepka, Shalini Chopra
CDCP1 mRNA expression by pathologic stage in the TCGA dataset. p=0.72 by Kruskal-Wallis test.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63b6206729334a8beb4e3fe99eefa862
https://doi.org/10.1158/1078-0432.22490227
https://doi.org/10.1158/1078-0432.22490227
Autor:
Michael J. Evans, Jonathan Chou, James A. Wells, Felix Y. Feng, Nima Hooshdaran, Ning Zhao, Kevin Leung, Jie Zhou, Emily Egusa, Jun Zhu, Alberto Carretero-González, Sasank Sakhamuri, Kai Trepka, Shalini Chopra
CDCP1 mRNA is overexpressed in basal/squamous subtypes of bladder cancer, related to Figure 1A-D. Pairwise comparisons of CDCP1 expression between bladder cancer consensus subtypes using the Wilcoxon rank-sum test across four different datasets are s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2de8a902264c380b363c4d25919ffc2
https://doi.org/10.1158/1078-0432.22490197.v1
https://doi.org/10.1158/1078-0432.22490197.v1