Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Sarvani Uppati"'
Autor:
Ramiro Oquita, Victoria Cuello, Sarvani Uppati, Sravani Mannuru, Daniel Salinas, Michael Dobbs, Kelsey A. Potter-Baker
Publikováno v:
Frontiers in Neurology, Vol 15 (2024)
Stroke results in varying levels of motor and sensory disability that have been linked to the neurodegeneration and neuroinflammation that occur in the infarct and peri-infarct regions within the brain. Specifically, previous research has identified
Externí odkaz:
https://doaj.org/article/19a65f68474f43679166b886d938665e
Autor:
William E. Carson, Stephen V. Liu, Michael A. Caligiuri, John C. Byrd, Susheela Tridandapani, Panos Savvides, Theodoros N. Teknos, Thomas Olencki, Bonnie Paul, Sarvani Uppati, Akaansha Ganju, Tiffany Noel, Gonzalo N. Olaverria Salavaggione, Kala Levine, Kyle Martin, Kallan Williams, Megan C. Duggan, Amanda R. Campbell, Melanie E. Davis, Xiaokui Mo, Nicholas B. Courtney, Lakhvir S. Atwal, Brooke Benner, Elizabeth L. McMichael
Supplemental Figure S1. Levels of serum cytokines in patients over the course of treatment. Serum levels of the cytokines IFN-γ (A), IP-10 (B), TNF-α (C) MIP-1α (D), MIP-1β (E), RANTES (F), GM CSF (G), and IL-8 (H) were measured at baseline and d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8119893f10dcaa84d086ec6e94a7d410
https://doi.org/10.1158/1078-0432.22473654.v1
https://doi.org/10.1158/1078-0432.22473654.v1
Autor:
William E. Carson, Stephen V. Liu, Michael A. Caligiuri, John C. Byrd, Susheela Tridandapani, Panos Savvides, Theodoros N. Teknos, Thomas Olencki, Bonnie Paul, Sarvani Uppati, Akaansha Ganju, Tiffany Noel, Gonzalo N. Olaverria Salavaggione, Kala Levine, Kyle Martin, Kallan Williams, Megan C. Duggan, Amanda R. Campbell, Melanie E. Davis, Xiaokui Mo, Nicholas B. Courtney, Lakhvir S. Atwal, Brooke Benner, Elizabeth L. McMichael
Supplemental Figure Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b64ca0fa43e0f3983071c3c1c40f659
https://doi.org/10.1158/1078-0432.22473657.v1
https://doi.org/10.1158/1078-0432.22473657.v1
Autor:
William E. Carson, Stephen V. Liu, Michael A. Caligiuri, John C. Byrd, Susheela Tridandapani, Panos Savvides, Theodoros N. Teknos, Thomas Olencki, Bonnie Paul, Sarvani Uppati, Akaansha Ganju, Tiffany Noel, Gonzalo N. Olaverria Salavaggione, Kala Levine, Kyle Martin, Kallan Williams, Megan C. Duggan, Amanda R. Campbell, Melanie E. Davis, Xiaokui Mo, Nicholas B. Courtney, Lakhvir S. Atwal, Brooke Benner, Elizabeth L. McMichael
Purpose:mAbs including cetuximab can induce antibody-dependent cellular cytotoxicity (ADCC) and cytokine production mediated via innate immune cells with the ability to recognize mAb-coated tumors. Preclinical modeling has shown that costimulation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13ffeabc0c1eb9b4a77c33bc87dcefcf
https://doi.org/10.1158/1078-0432.c.6528570
https://doi.org/10.1158/1078-0432.c.6528570
Autor:
William E. Carson, Stephen V. Liu, Michael A. Caligiuri, John C. Byrd, Susheela Tridandapani, Panos Savvides, Theodoros N. Teknos, Thomas Olencki, Bonnie Paul, Sarvani Uppati, Akaansha Ganju, Tiffany Noel, Gonzalo N. Olaverria Salavaggione, Kala Levine, Kyle Martin, Kallan Williams, Megan C. Duggan, Amanda R. Campbell, Melanie E. Davis, Xiaokui Mo, Nicholas B. Courtney, Lakhvir S. Atwal, Brooke Benner, Elizabeth L. McMichael
Supplementary Table 1. Toxicities; Supplementary Table 2. Patient characteristics and response evaluation; Supplementary Table 3. Patient Correlative Study Results
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5557c5dd079ea9de46f510ea6a57cb1e
https://doi.org/10.1158/1078-0432.22473651.v1
https://doi.org/10.1158/1078-0432.22473651.v1
Autor:
Amanda Campbell, Akaansha Ganju, Stephen V. Liu, Sarvani Uppati, Kala M. Levine, Bonnie Paul, Tiffany Noel, Elizabeth L. McMichael, Gonzalo N. Olaverria Salavaggione, Panos Savvides, William E. Carson, Melanie E. Davis, Lakhvir S. Atwal, Michael A. Caligiuri, Theodoros N. Teknos, Nicholas B. Courtney, Thomas Olencki, Kallan Williams, Megan C. Duggan, Brooke Benner, Susheela Tridandapani, Kyle A. Martin, Xiaokui Mo, John C. Byrd
Publikováno v:
Clin Cancer Res
Purpose: mAbs including cetuximab can induce antibody-dependent cellular cytotoxicity (ADCC) and cytokine production mediated via innate immune cells with the ability to recognize mAb-coated tumors. Preclinical modeling has shown that costimulation o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66fcefe11987d7a560074b271108d065
https://europepmc.org/articles/PMC6697573/
https://europepmc.org/articles/PMC6697573/
Autor:
J. Harrison Howard, Naduparambil K. Jacob, Kala M. Levine, Zachary B. Abrams, William E. Carson, Tanios Bekaii-Saab, Lai Wei, Joseph Markowitz, Kelly Regan, John N Hassani, Gregory B. Lesinski, Xiaoli Zhang, Taylor R. Brooks, Kari Kendra, Thomas Olencki, Nicholas Latchana, Sarvani Uppati, Philip R. O. Payne
Publikováno v:
OncoTargets and therapy
Joseph Markowitz,1–4 Zachary Abrams,2,5 Naduparambil K Jacob,2,6 Xiaoli Zhang,2,7 John N Hassani,1 Nicholas Latchana,8 Lai Wei,2,7 Kelly E Regan,2,5 Taylor R Brooks,2 Sarvani R Uppati,2 Kala M Levine,2 Tanios Bekaii-Saab,2,4 Kari L Kendra,2,4 Grego
Autor:
Elizabeth L. McMichael, Ian Landi, Yiming Zhong, Robert Wesolowski, Andrew Stiff, William E. Carson, Sarvani Uppati, Bonnie K. Harrington, Vincent Hsu, Prashant Trikha, John C. Byrd, Natarajan Muthusamy, Karen A. Keller, Michael A. Caligiuri, John Harrison Howard, Lianbo Yu, Sean D. Reiff, Matthew O. Old, Jason A. Dubovsky, Thomas A. Mace, Amanda Campbell, Kari Kendra, Megan C. Duggan, Susheela Tridandapani
Publikováno v:
Cancer research. 76(8)
Myeloid-derived suppressor cells (MDSC) are a heterogeneous group of immature myeloid cells that expand in tumor-bearing hosts in response to soluble factors produced by tumor and stromal cells. MDSC expansion has been linked to loss of immune effect
Autor:
Robert Wesolowski, Andrew Stiff, Natarajan Muthusamy, John C. Byrd, David Abood, Elizabeth L. McMichael, Amanda Campbell, Prashant Trikha, Sarvani Uppati, Michael Caliguiri, William E. Carson, Megan C. Duggan, Susheela Tridandapani, Kari Kendra
Publikováno v:
Cancer Research. 76:553-553
Myeloid derived suppressor cells (MDSC) interfere with anti tumor immune responses. MDSC have also been shown to antagonize the effectiveness of immune based therapies including immune checkpoint blockade. As a result, MDSC have received attention as
Autor:
Elizabeth L. McMichael, Panayiotis Savvides, Tiffany Noel, Kala M. Levine, Bonnie Paul, Akansha Gansu, William E. Carson, Melanie E. Davis, Theodoros N. Teknos, Thomas Olencki, Megan C. Duggan, Kallan S. Opheim, Stephen V. Liu, Amanda Campbell, Gonzalo N. Olaverria Salavaggione, Lakhvir S. Atwal, Sarvani Uppati
Publikováno v:
Cancer Research. 76:CT143-CT143
Introduction: Preclinical investigations demonstrated that IL-12 significantly enhances the lytic actions and cytokine production of NK cells against cetuximab-coated HER1-positive SCCHN cell lines via synergistic activation of the MAP kinase pathway