Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Sarthak Sahoo"'
Autor:
Sarthak Sahoo, Soundharya Ramu, Madhumathy G. Nair, Maalavika Pillai, Beatriz P. San Juan, Heloisa Zaccaron Milioli, Susmita Mandal, Chandrakala M. Naidu, Apoorva D. Mavatkar, Harini Subramaniam, Arpita G. Neogi, Christine L. Chaffer, Jyothi S. Prabhu, Jason A. Somarelli, Mohit Kumar Jolly
Publikováno v:
iScience, Vol 27, Iss 7, Pp 110116- (2024)
Summary: Intra-tumoral phenotypic heterogeneity promotes tumor relapse and therapeutic resistance and remains an unsolved clinical challenge. Decoding the interconnections among different biological axes of plasticity is crucial to understand the mol
Externí odkaz:
https://doaj.org/article/184f963418524796bef6f9437338f851
Autor:
Antara Biswas, Sarthak Sahoo, Gregory M. Riedlinger, Saum Ghodoussipour, Mohit K. Jolly, Subhajyoti De
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-18 (2023)
Abstract Intra-tumor heterogeneity contributes to treatment failure and poor survival in urothelial bladder carcinoma (UBC). Analyzing transcriptome from a UBC cohort, we report that intra-tumor transcriptomic heterogeneity indicates co-existence of
Externí odkaz:
https://doaj.org/article/da760c2ba979429ea0c8f52471d43aa0
Autor:
Madhumathy G. Nair, Apoorva D. Mavatkar, Chandrakala M. Naidu, Snijesh V. P., Anupama C. E., Savitha Rajarajan, Sarthak Sahoo, Gayathri Mohan, Vishnu Sunil Jaikumar, Rakesh S. Ramesh, Srinath B. S., Mohit Kumar Jolly, Tessy Thomas Maliekal, Jyothi S. Prabhu
Publikováno v:
Cells, Vol 13, Iss 10, p 821 (2024)
Epigenetic alterations that lead to differential expression of microRNAs (miRNAs/miR) are known to regulate tumour cell states, epithelial–mesenchymal transition (EMT) and the progression to metastasis in breast cancer. This study explores the key
Externí odkaz:
https://doaj.org/article/874df002e4e34366b454d0424b34efdd
Publikováno v:
Molecular Oncology, Vol 17, Iss 6, Pp 1041-1059 (2023)
Induction of immunoproteasome (IP) expression in tumour cells can enhance antigen presentation and immunogenicity. Recently, the overexpression of IP genes has been associated with better prognosis and response to immune checkpoint blockade (ICB) the
Externí odkaz:
https://doaj.org/article/1e802d87bc5a48c4bb7b4fa5a37daf3a
Autor:
Ayalur Raghu Subbalakshmi, Sarthak Sahoo, Prakruthi Manjunatha, Shaurya Goyal, Vignesh A Kasiviswanathan, Yeshwanth Mahesh, Soundharya Ramu, Isabelle McMullen, Jason A. Somarelli, Mohit Kumar Jolly
Publikováno v:
Journal of Biological Engineering, Vol 17, Iss 1, Pp 1-16 (2023)
Abstract Background Epithelial-mesenchymal plasticity (EMP) involves bidirectional transitions between epithelial, mesenchymal and multiple intermediary hybrid epithelial/mesenchymal phenotypes. While the process of epithelial-mesenchymal transition
Externí odkaz:
https://doaj.org/article/4fb827dce11f464388ebd3aef912b8ec
Autor:
Seemadri Subhadarshini, Sarthak Sahoo, Shibjyoti Debnath, Jason A Somarelli, Mohit Kumar Jolly
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 9 (2023)
Background Phenotypic heterogeneity of melanoma cells contributes to drug tolerance, increased metastasis, and immune evasion in patients with progressive disease. Diverse mechanisms have been individually reported to shape extensive intra-tumor and
Externí odkaz:
https://doaj.org/article/7eb5001b8c214a1aaf71fade4f0f0d83
Autor:
Vijaya Majumdar, N. K. Manjunath, Raghuram Nagarathna, Suryanarayan Panigrahi, Muralidhar Kanchi, Sarthak Sahoo, Hongasandra R. Nagendra, Adithi Giridharan, Mounika Reddy, Rakshitha Nayak
Publikováno v:
Frontiers in Public Health, Vol 11 (2023)
BackgroundThe initial insights from the studies on COVID-19 had been disappointing, indicating the necessity of an aggravated search for alternative strategies. In this regard, the adjunct potential of yoga has been proposed for enhancing the effecti
Externí odkaz:
https://doaj.org/article/4dfe928312664867a6e1e7181ca0438c
Autor:
Vaishali Aggarwal, Sarthak Sahoo, Vera S. Donnenberg, Priyanka Chakraborty, Mohit Kumar Jolly, Shilpa Sant
Publikováno v:
Advances in Cancer Biology - Metastasis, Vol 5, Iss , Pp 100057- (2022)
Epithelial-to-mesenchymal transition (EMT), a well-established phenomenon studied across pan-cancer types, has long been known to be a major player in driving tumor invasion and metastasis. Recent studies have highlighted the importance of partial EM
Externí odkaz:
https://doaj.org/article/1febb7dc79cd448ca3c431012502bf73
Publikováno v:
iScience, Vol 25, Iss 9, Pp 104955- (2022)
Summary: The immense regenerative potential of the liver is attributed to the ability of its two key cell types – hepatocytes and cholangiocytes – to trans-differentiate to one another either directly or through intermediate progenitor states. Ho
Externí odkaz:
https://doaj.org/article/62d9bb7073324bedb4c4534f669b8db3
Autor:
Viola Hedrich, Kristina Breitenecker, Gregor Ortmayr, Franziska Pupp, Heidemarie Huber, Doris Chen, Sarthak Sahoo, Mohit Kumar Jolly, Wolfgang Mikulits
Publikováno v:
Cancers, Vol 15, Iss 9, p 2415 (2023)
(1) Background: Activation of the receptor tyrosine kinase Axl by Gas6 fosters oncogenic effects in hepatocellular carcinoma (HCC), associating with increased mortality of patients. The impact of Gas6/Axl signaling on the induction of individual targ
Externí odkaz:
https://doaj.org/article/4b1c2f139f2545a19dd88ede30b2b57a