Výsledky vyhledávání - "Sartaj Baidwan"

Glucotoxicity promotes aberrant activation and mislocalization of Ras-related C3 botulinum toxin substrate 1 [Rac1] and metabolic dysfunction in pancreatic islet β-cells: Reversal of such metabolic defects by metformin

Autor: DiAnna L. Hynds, Sartaj Baidwan, Anjaneyulu Kowluru, Anil Chekuri

Emerging evidence suggests that long-term exposure of insulin-secreting pancreatic β-cells to hyperglycemic (HG; glucotoxic) conditions promotes oxidative stress, which, in turn, leads to stress kinase activation, mitochondrial dysfunction, loss of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44cf2b9e12d5c723961720821f98d3dc
https://europepmc.org/articles/PMC5643241/

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