Calibrating Observational Health Record Data Against a Randomized Trial.

Autor: Merola D; Aetion, New York, New York., Campbell U; Aetion, New York, New York., Lenis D; Aetion, New York, New York., Schneeweiss S; Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts., Wang S; Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts., Madsen A; Aetion, New York, New York., Carrigan G; Center for Observational Research, Amgen, San Francisco, California., Chia V; Center for Observational Research, Amgen, San Francisco, California., Ovbiosa OE; AbbVie, North Chicago, Illinois., Pinheiro S; AbbVie, North Chicago, Illinois., Pace N; AbbVie, North Chicago, Illinois., Bruno A; Bayer Pharmaceuticals, Philadelphia, Pennsylvania., Stewart M; Friends of Cancer Research, Washington, District of Columbia., Khosla S; AstraZeneca, Gaithersburg, Maryland., Zhang Y; AstraZeneca, Gaithersburg, Maryland., Rimawi M; Baylor College of Medicine, Houston, Texas., Hendricks-Sturrup R; Duke-Margolis Center for Health Policy, Washington, District of Columbia., Huang J; Gilead Sciences, Foster City, California., Taylor A; Gilead Sciences, Foster City, California., Jiao X; Pfizer, New York, New York., Becnel L; Pfizer, New York, New York., McRoy L; Pfizer, New York, New York., Eckert J; Reagan-Udall Foundation for the Food and Drug Administration, Washington, District of Columbia., Rodriguez C; Reagan-Udall Foundation for the Food and Drug Administration, Washington, District of Columbia., Lunacsek O; Bayer Pharmaceuticals, Whippany, New Jersey., Harvey R; Johnson & Johnson, New Brunswick, New Jersey., Greshock J; Johnson & Johnson, New Brunswick, New Jersey., Sarsour K; Johnson & Johnson, New Brunswick, New Jersey., Belli A; COTA Healthcare, New York, New York., Wang CK; COTA Healthcare, New York, New York., Fernandes L; COTA Healthcare, New York, New York., Chen J; Tempus, Chicago, Illinois., San Francisco B; Tempus, Chicago, Illinois., Sangli C; Tempus, Chicago, Illinois., Natanzon Y; ConcertAI, Cambridge, Massachusetts., Chan KA; TriNetX, Cambridge, Massachusetts., Dhopeshwarkar N; TriNetX, Cambridge, Massachusetts., Shapiro M; xCures, Oakland, California., Wasserman A; xCures, Oakland, California., Quinn J; xCures, Oakland, California., Rees M; Loopback Analytics, Dallas, Texas., Robinson T; Loopback Analytics, Dallas, Texas., Taylor B; Aetion, New York, New York., Rider JR; Aetion, New York, New York.

Publikováno v: JAMA network open [JAMA Netw Open] 2024 Sep 03; Vol. 7 (9), pp. e2436535. Date of Electronic Publication: 2024 Sep 03.

Enhancing site selection strategies in clinical trial recruitment using real-world data modeling.

Autor: Hulstaert L; R&D Data Science & Digital Health, Janssen-Cilag GmbH, Neuss, North Rhine-Westphalia, Germany., Twick I; R&D Data Science & Digital Health, Janssen-Cilag GmbH, Neuss, North Rhine-Westphalia, Germany., Sarsour K; R&D Data Science & Digital Health, Janssen Pharmaceuticals, Titusville, New Jersey, United States of America., Verstraete H; R&D Data Science & Digital Health, Janssen Pharmaceutica NV, Beerse, Antwerp, Belgium.

Publikováno v: PloS one [PLoS One] 2024 Mar 11; Vol. 19 (3), pp. e0300109. Date of Electronic Publication: 2024 Mar 11 (Print Publication: 2024).

RWD85 An Emulation of the KEYNOTE-189 Trial Using Electronic Health Records

Autor: Merola, D, Campbell, U, Lenis, D, Madsen, A, Schneeweiss, S, Wang, S, Carrigan, G, Taylor, A, Huang, J, Chia, VM, Ovbiosa, O, Pinheiro, S, Pace, ND, Bruno, A, Stewart, M, Khosla, S, Zhang, Y, Rimawi, M, Hendricks-Sturrup, R, Locke, T, Jiao, X, Becnel, L, McRoy, L, Rabon-Stith, K, Eckert, JC, Rodriguez-Watson, C, Lunacsek, O, Harvey, R, Greshock, J, Sarsour, K, Belli, A, Wang, C, Fernandes, L, Chen, J, Natanzon, Y, Dhopeshwarkar, N, Wasserman, A, Quinn, J, Taylor, B, Rider, J

Publikováno v: In Value in Health June 2024 27(6) Supplement:S373-S374

Durability of Protection Post-Primary COVID-19 Vaccination in the United States.

Autor: Zheutlin A; Data Sciences, Research & Development, Janssen Pharmaceuticals, Titusville, NJ 08560, USA., Ott M; Data Sciences, Research & Development, Janssen Pharmaceuticals, Titusville, NJ 08560, USA., Sun R; Data Sciences, Research & Development, Janssen Pharmaceuticals, Titusville, NJ 08560, USA., Zemlianskaia N; Data Sciences, Research & Development, Janssen Pharmaceuticals, Titusville, NJ 08560, USA., Meyer CS; Data Sciences, Research & Development, Janssen Pharmaceuticals, Titusville, NJ 08560, USA., Rubel M; Data Sciences, Research & Development, Janssen Pharmaceuticals, Titusville, NJ 08560, USA., Hayden J; Data Sciences, Research & Development, Janssen Pharmaceuticals, Titusville, NJ 08560, USA., Neri B; Data Sciences, Research & Development, Janssen Pharmaceuticals, Titusville, NJ 08560, USA., Kamath T; Data Sciences, Research & Development, Janssen Pharmaceuticals, Titusville, NJ 08560, USA., Khan N; Data Sciences, Research & Development, Janssen Pharmaceuticals, Titusville, NJ 08560, USA., Schneeweiss S; Division of Pharmacoepidemiology, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02120, USA., Sarsour K; Data Sciences, Research & Development, Janssen Pharmaceuticals, Titusville, NJ 08560, USA.

Publikováno v: Vaccines [Vaccines (Basel)] 2022 Sep 03; Vol. 10 (9). Date of Electronic Publication: 2022 Sep 03.

Impact of Immune Checkpoint Inhibitors on COVID-19 Severity in Patients with Cancer.

Autor: Tan R; U.S. Medical Affairs, Genentech, Inc., South San Francisco, CA, USA., Yun C; U.S. Medical Affairs, Genentech, Inc., South San Francisco, CA, USA., Seetasith A; U.S. Medical Affairs, Genentech, Inc., South San Francisco, CA, USA., Sheinson D; U.S. Medical Affairs, Genentech, Inc., South San Francisco, CA, USA., Walls R; Safety and Risk Management, Product Development, F. Hoffmann-La Roche AG, Basel, Switzerland., Ngwa I; Safety and Risk Management, Product Development, F. Hoffmann-La Roche AG, Basel, Switzerland., Reddy JC; Safety and Risk Management, Product Development, F. Hoffmann-La Roche AG, Basel, Switzerland., Zhang Q; Personalized Healthcare Data Science, Global Product Development, Genentech, South San Francisco, CA, USA., Secrest MH; Personalized Healthcare Data Science, Global Product Development, Genentech, South San Francisco, CA, USA., Lambert P; Personalized Healthcare Data Science, Global Product Development, Genentech, South San Francisco, CA, USA., Sarsour K; Personalized Healthcare Data Science, Global Product Development, Genentech, South San Francisco, CA, USA.

Publikováno v: The oncologist [Oncologist] 2022 Mar 11; Vol. 27 (3), pp. 236-243.