Novel human pluripotent stem cell-derived hypothalamus organoids demonstrate cellular diversity

Autor: Sarrafha, Lily, Neavin, Drew R., Parfitt, Gustavo M., Kruglikov, Ilya A., Whitney, Kristen, Reyes, Ricardo, Coccia, Elena, Kareva, Tatyana, Goldman, Camille, Tipon, Regine, Croft, Gist, Crary, John F., Powell, Joseph E., Blanchard, Joel, Ahfeldt, Tim

Publikováno v: In iScience 15 September 2023 26(9)

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Disruption of lysosomal proteolysis in astrocytes facilitates midbrain organoid proteostasis failure in an early-onset Parkinson's disease model.

Autor: Morrone Parfitt, Gustavo, Coccia, Elena, Goldman, Camille, Whitney, Kristen, Reyes, Ricardo, Sarrafha, Lily, Nam, Ki Hong, Sohail, Soha, Jones, Drew R., Crary, John F., Ordureau, Alban, Blanchard, Joel, Ahfeldt, Tim

Publikováno v: Nature Communications; 1/10/2024, Vol. 15 Issue 1, p1-17, 17p

A reference human induced pluripotent stem cell line for collaborative studies

Autor: Pantazis, Caroline B, Yang, Andrian, Lara, Erika, McDonough, Justin A, Blauwendraat, Cornelis, Peng, Lirong, Oguro, Hideyuki, Kanaujiya, Jitendra, Zou, Jizhong, Sebesta, David, Pratt, Gretchen, Cross, Erin, Blockwick, Jeffrey, Buxton, Philip, Kinner-Bibeau, Lauren, Medura, Constance, Tompkins, Christopher, Hughes, Stephen, Santiana, Marianita, Faghri, Faraz, Nalls, Mike A, Vitale, Daniel, Ballard, Shannon, Qi, Yue A, Ramos, Daniel M, Anderson, Kailyn M, Stadler, Julia, Narayan, Priyanka, Papademetriou, Jason, Reilly, Luke, Nelson, Matthew P, Aggarwal, Sanya, Rosen, Leah U, Kirwan, Peter, Pisupati, Venkat, Coon, Steven L, Scholz, Sonja W, Priebe, Theresa, Ottl, Miriam, Dong, Jian, Meijer, Marieke, Janssen, Lara JM, Lourenco, Vanessa S, van der Kant, Rik, Crusius, Dennis, Paquet, Dominik, Raulin, Ana-Caroline, Bu, Guojun, Held, Aaron, Wainger, Brian J, Gabriele, Rebecca MC, Casey, Jackie M, Wray, Selina, Abu-Bonsrah, Dad, Parish, Clare L, Beccari, Melinda S, Cleveland, Don W, Li, Emmy, Rose, Indigo VL, Kampmann, Martin, Aristoy, Carles Calatayud, Verstreken, Patrik, Heinrich, Laurin, Chen, Max Y, Schule, Birgitt, Dou, Dan, Holzbaur, Erika LF, Zanellati, Maria Clara, Basundra, Richa, Deshmukh, Mohanish, Cohen, Sarah, Khanna, Richa, Raman, Malavika, Nevin, Zachary S, Matia, Madeline, Van Lent, Jonas, Timmerman, Vincent, Conklin, Bruce R, Chase, Katherine Johnson, Zhang, Ke, Funes, Salome, Bosco, Daryl A, Erlebach, Lena, Welzer, Marc, Kronenberg-Versteeg, Deborah, Lyu, Guochang, Arenas, Ernest, Coccia, Elena, Sarrafha, Lily, Ahfeldt, Tim, Marioni, John C, Skarnes, William C, Cookson, Mark R, Ward, Michael E, Merkle, Florian T

Human induced pluripotent stem cell (iPSC) lines are a powerful tool for studying development and disease, but the considerable phenotypic variation between lines makes it challenging to replicate key findings and integrate data across research group

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1131::558c404ec1b063eb6992b0688aa07a2d
https://lirias.kuleuven.be/handle/20.500.12942/715880

Investigating mechanisms of sporadic progressive supranuclear palsy in autopsy‐validated human iPSC‐derived midbrain organoids and human brain tissue.

Autor: Whitney, Kristen R., Krassner, Margaret M., Delica, Sean Thomas, Farrell, Kurt W., Kim, SoongHo, Dangoor, Diana K., Sharma, Abhijeet, Song, Won‐Min, Christie, Thomas D., Iida, Megan A, Walsh, Hadley A., Sarrafha, Lily, Parfitt, Gustavo, Walker, Ruth H., Riboldi, Giulietta M., Frucht, Steven J., Ahfeldt, Tim, Zhang, Bin, Pereira, Ana C., Temple, Sally

Publikováno v: Alzheimer's & Dementia: The Journal of the Alzheimer's Association; Dec2023 Supplement 13, Vol. 19, p1-2, 2p