Cryptic aberrations may allow more accurate prognostic classification of patients with myelodysplastic syndromes and clonal evolution.

Autor: Svobodova K; Center of Oncocytogenomics, Institute of Medical Biochemistry and Laboratory Diagnostics, General University Hospital and First Faculty of Medicine, Charles University in Prague, Prague, Czech Republic.; First Faculty of Medicine, Charles University in Prague, Prague, Czech Republic., Lhotska H; Center of Oncocytogenomics, Institute of Medical Biochemistry and Laboratory Diagnostics, General University Hospital and First Faculty of Medicine, Charles University in Prague, Prague, Czech Republic., Hodanova L; Center of Oncocytogenomics, Institute of Medical Biochemistry and Laboratory Diagnostics, General University Hospital and First Faculty of Medicine, Charles University in Prague, Prague, Czech Republic., Pavlistova L; Center of Oncocytogenomics, Institute of Medical Biochemistry and Laboratory Diagnostics, General University Hospital and First Faculty of Medicine, Charles University in Prague, Prague, Czech Republic., Vesela D; Center of Oncocytogenomics, Institute of Medical Biochemistry and Laboratory Diagnostics, General University Hospital and First Faculty of Medicine, Charles University in Prague, Prague, Czech Republic., Belickova M; Institute of Hematology and Blood Transfusion, Prague, Czech Republic., Vesela J; Institute of Hematology and Blood Transfusion, Prague, Czech Republic., Brezinova J; Institute of Hematology and Blood Transfusion, Prague, Czech Republic., Sarova I; Center of Oncocytogenomics, Institute of Medical Biochemistry and Laboratory Diagnostics, General University Hospital and First Faculty of Medicine, Charles University in Prague, Prague, Czech Republic.; Institute of Hematology and Blood Transfusion, Prague, Czech Republic., Izakova S; Center of Oncocytogenomics, Institute of Medical Biochemistry and Laboratory Diagnostics, General University Hospital and First Faculty of Medicine, Charles University in Prague, Prague, Czech Republic., Lizcova L; Center of Oncocytogenomics, Institute of Medical Biochemistry and Laboratory Diagnostics, General University Hospital and First Faculty of Medicine, Charles University in Prague, Prague, Czech Republic., Siskova M; First Medical Department, General University Hospital and First Faculty of Medicine, Charles University in Prague, Prague, Czech Republic., Jonasova A; First Medical Department, General University Hospital and First Faculty of Medicine, Charles University in Prague, Prague, Czech Republic., Cermak J; Institute of Hematology and Blood Transfusion, Prague, Czech Republic., Michalova K; Center of Oncocytogenomics, Institute of Medical Biochemistry and Laboratory Diagnostics, General University Hospital and First Faculty of Medicine, Charles University in Prague, Prague, Czech Republic., Zemanova Z; Center of Oncocytogenomics, Institute of Medical Biochemistry and Laboratory Diagnostics, General University Hospital and First Faculty of Medicine, Charles University in Prague, Prague, Czech Republic.; First Faculty of Medicine, Charles University in Prague, Prague, Czech Republic.

Publikováno v: Genes, chromosomes & cancer [Genes Chromosomes Cancer] 2020 Jul; Vol. 59 (7), pp. 396-405. Date of Electronic Publication: 2020 Mar 25.

High frequency of dicentric chromosomes detected by multi-centromeric FISH in patients with acute myeloid leukemia and complex karyotype.

Autor: Sarova I; Institute of Hematology and Blood Transfusion, U Nemocnice 1, 128 20 Prague 2, Czech Republic; Center of Oncocytogenetics, Institute of Medical Biochemistry and Laboratory Diagnostics, General University Hospital and First Faculty of Medicine, Charles University, U Nemocnice 2, 128 08, Prague 2, Czech Republic. Electronic address: iveta.sarova@uhkt.cz., Brezinova J; Institute of Hematology and Blood Transfusion, U Nemocnice 1, 128 20 Prague 2, Czech Republic., Zemanova Z; Center of Oncocytogenetics, Institute of Medical Biochemistry and Laboratory Diagnostics, General University Hospital and First Faculty of Medicine, Charles University, U Nemocnice 2, 128 08, Prague 2, Czech Republic., Ransdorfova S; Institute of Hematology and Blood Transfusion, U Nemocnice 1, 128 20 Prague 2, Czech Republic., Svobodova K; Center of Oncocytogenetics, Institute of Medical Biochemistry and Laboratory Diagnostics, General University Hospital and First Faculty of Medicine, Charles University, U Nemocnice 2, 128 08, Prague 2, Czech Republic., Izakova S; Center of Oncocytogenetics, Institute of Medical Biochemistry and Laboratory Diagnostics, General University Hospital and First Faculty of Medicine, Charles University, U Nemocnice 2, 128 08, Prague 2, Czech Republic., Pavlistova L; Center of Oncocytogenetics, Institute of Medical Biochemistry and Laboratory Diagnostics, General University Hospital and First Faculty of Medicine, Charles University, U Nemocnice 2, 128 08, Prague 2, Czech Republic., Lizcova L; Center of Oncocytogenetics, Institute of Medical Biochemistry and Laboratory Diagnostics, General University Hospital and First Faculty of Medicine, Charles University, U Nemocnice 2, 128 08, Prague 2, Czech Republic., Berkova A; Center of Oncocytogenetics, Institute of Medical Biochemistry and Laboratory Diagnostics, General University Hospital and First Faculty of Medicine, Charles University, U Nemocnice 2, 128 08, Prague 2, Czech Republic., Skipalova K; Center of Oncocytogenetics, Institute of Medical Biochemistry and Laboratory Diagnostics, General University Hospital and First Faculty of Medicine, Charles University, U Nemocnice 2, 128 08, Prague 2, Czech Republic., Hodanova L; Center of Oncocytogenetics, Institute of Medical Biochemistry and Laboratory Diagnostics, General University Hospital and First Faculty of Medicine, Charles University, U Nemocnice 2, 128 08, Prague 2, Czech Republic., Salek C; Institute of Hematology and Blood Transfusion, U Nemocnice 1, 128 20 Prague 2, Czech Republic., Jonasova A; 1st Department of Internal Medicine of General University Hospital and 1st Faculty of Medicine, Charles University, U Nemocnice 2, 128 08, Prague 2, Czech Republic., Michalova K; Institute of Hematology and Blood Transfusion, U Nemocnice 1, 128 20 Prague 2, Czech Republic; Center of Oncocytogenetics, Institute of Medical Biochemistry and Laboratory Diagnostics, General University Hospital and First Faculty of Medicine, Charles University, U Nemocnice 2, 128 08, Prague 2, Czech Republic.

Publikováno v: Leukemia research [Leuk Res] 2018 May; Vol. 68, pp. 85-89. Date of Electronic Publication: 2018 Mar 19.

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K zobrazení výsledku je třeba se přihlásit.

MethScore as a new comprehensive DNA methylation-based value refining the prognosis in acute myeloid leukemia.

Autor: Šestáková, Šárka^1,2 (AUTHOR), Šálek, Cyril^1,2 (AUTHOR), Kundrát, Dávid¹ (AUTHOR), Cerovská, Ela^1,3 (AUTHOR), Vydra, Jan^1,2 (AUTHOR), Ježíšková, Ivana⁴ (AUTHOR), Folta, Adam⁴ (AUTHOR), Mayer, Jiří⁴ (AUTHOR), Cetkovský, Petr^1,2 (AUTHOR), Remešová, Hana¹ (AUTHOR) hana.remesova@uhkt.cz

Publikováno v: Clinical Epigenetics. 1/22/2024, Vol. 16 Issue 1, p1-12. 12p.

Copy number neutral loss of heterozygosity at 17p and homozygous mutations of TP53 are associated with complex chromosomal aberrations in patients newly diagnosed with myelodysplastic syndromes.

Autor: Svobodova K; Center of Oncocytogenetics, Institute of Medical Biochemistry and Laboratory Diagnostics, General University Hospital and First Faculty of Medicine, Charles University in Prague, Czech Republic. Electronic address: karla.svobodova@vfn.cz., Zemanova Z; Center of Oncocytogenetics, Institute of Medical Biochemistry and Laboratory Diagnostics, General University Hospital and First Faculty of Medicine, Charles University in Prague, Czech Republic., Lhotska H; Center of Oncocytogenetics, Institute of Medical Biochemistry and Laboratory Diagnostics, General University Hospital and First Faculty of Medicine, Charles University in Prague, Czech Republic., Novakova M; Center of Oncocytogenetics, Institute of Medical Biochemistry and Laboratory Diagnostics, General University Hospital and First Faculty of Medicine, Charles University in Prague, Czech Republic., Podskalska L; Center of Oncocytogenetics, Institute of Medical Biochemistry and Laboratory Diagnostics, General University Hospital and First Faculty of Medicine, Charles University in Prague, Czech Republic., Belickova M; Institute of Hematology and Blood Transfusion, Prague, Czech Republic., Brezinova J; Institute of Hematology and Blood Transfusion, Prague, Czech Republic., Sarova I; Center of Oncocytogenetics, Institute of Medical Biochemistry and Laboratory Diagnostics, General University Hospital and First Faculty of Medicine, Charles University in Prague, Czech Republic; Institute of Hematology and Blood Transfusion, Prague, Czech Republic., Izakova S; Center of Oncocytogenetics, Institute of Medical Biochemistry and Laboratory Diagnostics, General University Hospital and First Faculty of Medicine, Charles University in Prague, Czech Republic., Lizcova L; Center of Oncocytogenetics, Institute of Medical Biochemistry and Laboratory Diagnostics, General University Hospital and First Faculty of Medicine, Charles University in Prague, Czech Republic., Berkova A; Center of Oncocytogenetics, Institute of Medical Biochemistry and Laboratory Diagnostics, General University Hospital and First Faculty of Medicine, Charles University in Prague, Czech Republic., Siskova M; First Medical Department, General University Hospital and First Faculty of Medicine, Charles University in Prague, Czech Republic., Jonasova A; First Medical Department, General University Hospital and First Faculty of Medicine, Charles University in Prague, Czech Republic., Cermak J; Institute of Hematology and Blood Transfusion, Prague, Czech Republic., Michalova K; Center of Oncocytogenetics, Institute of Medical Biochemistry and Laboratory Diagnostics, General University Hospital and First Faculty of Medicine, Charles University in Prague, Czech Republic; Institute of Hematology and Blood Transfusion, Prague, Czech Republic.

Publikováno v: Leukemia research [Leuk Res] 2016 Mar; Vol. 42, pp. 7-12. Date of Electronic Publication: 2016 Jan 24.