Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Sarojani Angal"'
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology. 1203:147-154
Tissue inhibitor of metalloproteinases-1 (TIMP-1) was treated with a range of chemical modification reagents in order to identify amino acid residues essential for inhibitory activity. Diethyl pyrocarbonate (DEPC) was found to be a potent inactivator
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9fc73b55f5333eb06030292a6efb182
https://doi.org/10.1016/0167-4838(93)90049-w
https://doi.org/10.1016/0167-4838(93)90049-w
Publikováno v:
Biochemical Journal. 276:217-221
Recombinant human prostromelysin was purified in a single step using Procion Red-Sepharose chromatography. The purified prostromelysin was self-activated to high-Mr (45,000) and low-Mr (28,000) forms by incubation at 55 degrees C without the addition
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abb0d2408e7be761bee53964d5309d34
https://doi.org/10.1042/bj2760217
https://doi.org/10.1042/bj2760217
Autor:
Rosaline O. Kingaby, Francis Willenbrock, Janet Deistung, Bernadette Hughes, Cath Catterall, James O'Connell, Deidree M. Forde, Diane Eaton, Karen A. Proudfoot, John Spencer Emtage, Sarojani Angal, Sandy Carne
Publikováno v:
Journal of Chromatography A. 539:485-492
Recombinant DNA technology has been employed to produce a hybrid gene in which the kringle and serine protease domains of tissue plasminogen activator are linked to the heavy-chain Fd legion of a fibrin-specific antibody. The hybrid gene is co-expres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54608594d6f6d90420b7655735f2b744
https://doi.org/10.1016/s0021-9673(01)83958-3
https://doi.org/10.1016/s0021-9673(01)83958-3
Autor:
Sarojani Angal
The affinity of two kinases for Blue Dextran was discovered in 1968 during gel permeation chromatography (1) and agarose electrophoresis (2). The observed interaction was mediated by the chromophore of Blue Dextran, Cibacron Blue F3G-A (3), which was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::84bf2136d40761b36590638752ad4c4d
https://doi.org/10.1385/0-89603-126-8:111
https://doi.org/10.1385/0-89603-126-8:111
A single amino acid substitution abolishes the heterogeneity of chimeric mouse/human (IgG4) antibody
Autor:
John Robert Adair, B. Pedley, Sarojani Angal, Mark Bodmer, David J. King, A. Turner, Alastair David Griffiths Lawson, G. Roberts
Publikováno v:
Molecular immunology. 30(1)
Human immunoglobulin G4 (IgG4) exists in two molecular forms due to the heterogeneity of the inter-heavy chain disulphide bridges in the hinge region in a proportion of secreted human IgG4. This heterogeneity is only revealed under denaturing, non-re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::672061cd951de1b43bfd2af2e315f813
https://pubmed.ncbi.nlm.nih.gov/8417368
https://pubmed.ncbi.nlm.nih.gov/8417368
Publikováno v:
Trends in biotechnology. 10(6)
Uncontrolled matrix metalloproteinase activity is thought to be a cause of the tissue damage observed in many disease processes. None of the drugs currently in use can prevent tissue destruction, and strategies for the development of synthetic inhibi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1aa88d67f319ba96566a10653be4b1db
https://pubmed.ncbi.nlm.nih.gov/1368394
https://pubmed.ncbi.nlm.nih.gov/1368394
Autor:
D C Low, John Robert Adair, Geoffrey Yarranton, Sarojani Angal, K A Proudfoot, J. C. Lloyd, David J. King, Mark Bodmer
Publikováno v:
The Biochemical journal. 281
B72.3 is a mouse monoclonal antibody against a tumour-associated antigen, TAG72, which recognizes breast, ovarian and colorectal tumour tissue. A mouse-human chimeric version of B72.3 has been expressed in Chinese-hamster ovary cells. This molecule h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39627e3bda81d8fc4bba9fc688a3c917
https://pubmed.ncbi.nlm.nih.gov/1736881
https://pubmed.ncbi.nlm.nih.gov/1736881
Publikováno v:
Biochemical Society transactions. 19(4)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::216f8bd7fed203402d800eddd615bd43
https://pubmed.ncbi.nlm.nih.gov/1794505
https://pubmed.ncbi.nlm.nih.gov/1794505
Autor:
Peter A. Koklitis, A.F. Carne, Sarojani Angal, Robert B. Freedman, Harris T J R, Bryan J. Smith, Maria Panico, Howard R. Morris, F. A. O. Marston, Richard A. Williamson
Publikováno v:
The Biochemical journal. 268(2)
Disulphide bonds in human recombinant tissue inhibitor of metalloproteinases (TIMP) were assigned by resolving proteolytic digests of TIMP on reverse-phase h.p.l.c. and sequencing those peaks judged to contain disulphide bonds by virtue of a change i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5462f40f880a1583e16981c3f7adff38
https://pubmed.ncbi.nlm.nih.gov/2163605
https://pubmed.ncbi.nlm.nih.gov/2163605
Publikováno v:
Biochemical Society Transactions. 19:371S-371S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78ae9b3cc24b3ce642e1d9c51aef4194
https://doi.org/10.1042/bst019371s
https://doi.org/10.1042/bst019371s