Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Sarmistha Halder Sinha"'
Autor:
Snehajyoti Chatterjee, Raphaelle Cassel, Anne Schneider‐Anthony, Karine Merienne, Brigitte Cosquer, Laura Tzeplaeff, Sarmistha Halder Sinha, Manoj Kumar, Piyush Chaturbedy, Muthusamy Eswaramoorthy, Stéphanie Le Gras, Céline Keime, Olivier Bousiges, Patrick Dutar, Petnoi Petsophonsakul, Claire Rampon, Jean‐Christophe Cassel, Luc Buée, David Blum, Tapas K Kundu, Anne‐Laurence Boutillier
Publikováno v:
EMBO Molecular Medicine, Vol 10, Iss 11, Pp 1-20 (2018)
Abstract Chromatin acetylation, a critical regulator of synaptic plasticity and memory processes, is thought to be altered in neurodegenerative diseases. Here, we demonstrate that spatial memory and plasticity (LTD, dendritic spine formation) deficit
Externí odkaz:
https://doaj.org/article/3e3bcfa696b14836b0aa51926f42e2db
Autor:
Chandra Kumar Elechalawar, Sumana Chakravarty, Muthusamy Eswaramoorthy, Piyush Chaturbedy, Rajkumar Banerjee, Kathyayani Sridharan, Halley Gora, Sarmistha Halder Sinha, Madhan Mohan Chandra Sekhar Jaggarapu, Mohammed Tanveer Ahmed, Dwaipayan Bhattacharya, Tapas K. Kundu, Kumar Pranav Narayan
Publikováno v:
Nanoscale advances. 1(9)
Glioblastoma multiforme (GBM), the highly invasive form of glioma, exhibits the highest mortality in patients with brain malignancies. Increasing glioma patients' survivability is challenging, as targeting only tumor-associated malignant cells would
Publikováno v:
Pharmacological research. 132
The accumulation of somatic and genetic mutations which altered the structure and coding information of the DNA are the major cause of neurological disorders. However, our recent understanding of molecular mechanisms of ‘epigenetic’ phenomenon re
Autor:
Stephanie Kaypee, Sarmistha Halder Sinha, Smitha Asoka Sahadevan, Parijat Senapati, Azeem Mohiyuddin, Shilpa Patil, Deepthi Sudarshan, Gopinath S. Kodaganur, Tapas K. Kundu, Dipak Dasgupta
Publikováno v:
Biochimica et biophysica acta. General subjects. 1862(8)
Background p300 (KAT3B) lysine acetyltransferase activity is modulated under different physiological and pathological contexts through the induction of trans-autoacetylation. This phenomenon is mediated by several factors, mechanisms of which are not
Autor:
Sudhevan Surabhi, Siddhanta Soumik, Dipak Dasgupta, Pushpak Mizar, Tapas K. Kundu, Chandrabhas Narayana, Dhanasekaran Karthigeyan, Amrita Banerjee, Sarmistha Halder Sinha
Publikováno v:
Chemical biologydrug design. 87(6)
Aurora kinases are the most commonly targeted mitotic kinases in the intervention of cancer progression. Here, we report a resorcinol derivative, 5-methyl-4-(2-thiazolylazo) resorcinol (PTK66), a dual inhibitor of Aurora A and Aurora B kinases. PTK66
Autor:
Muthusamy Eswaramoorthy, Krishnachary Salikolimi, B. S. Suma, Piyush Chaturbedy, Sarmistha Halder Sinha, Manoj Kumar, Snehajyoti Chatterjee, Sadhan Das, Tapas K. Kundu
Publikováno v:
Journal of controlled release : official journal of the Controlled Release Society. 217
Targeted drug delivery to specific subcellular compartments of brain cells is challenging despite their importance in the treatment of several brain-related diseases. Herein, we report on shape-directed intracellular compartmentalization of nanoparti
Autor:
Kristin R. Di Bona, Sarmistha Halder Sinha, John B. Vincent, Jane F. Rasco, Sharifa Love, DeAna McAdory, Brittany R. Skinner
Publikováno v:
Biological trace element research. 152(1)
Over 50 years ago, chromium (Cr) was proposed to be an essential trace element; however, recent studies indicate that this status should be removed as the effects of Cr supplementation appear to be pharmacological rather than nutritional. The pharmac
Autor:
Heather M. Watson, Junjie Gao, Yuan Chen, Carolyn J. Cassady, John B. Vincent, Sarmistha Halder Sinha
Publikováno v:
The Journal of nutrition. 141(7)
Chromium was proposed to be an essential element over 50 y ago and was shown to have therapeutic potential in treating the symptoms of type 2 diabetes; however, its mechanism of action at a molecular level is unknown. One chromium-binding biomolecule
Autor:
Nicholas R. Rhodes, John B. Vincent, Jane F. Rasco, DeAna McAdory, Kristin R. Di Bona, Sarmistha Halder Sinha, James Ramage, Sharifa Love
Publikováno v:
The FASEB Journal. 25
Autor:
Austin Wilson, James Ramage, John B. Vincent, Nicholas R. Rhodes, Naomi Kern, Sarmistha Halder Sinha, Jane F. Rasco, Jessyln Strickland, DeAna McAdory, Kristin R. Di Bona, Sharifa Love, Janis Beaird, Julia Kent
Publikováno v:
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry. 16(3)
Chromium was proposed to be an essential trace element over 50 years ago and has been accepted as an essential element for over 30 years. However, the studies on which chromium’s status are based are methodologically flawed. Whether chromium is an