Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Sarmad Al-Marsoummi"'
Publikováno v:
Cancers, Vol 16, Iss 6, p 1178 (2024)
Bladder cancer (BC) is the eighth most common cause of cancer death in the United States of America. BC is classified into non-muscle-invasive bladder cancer (NMIBC) and muscle-invasive bladder cancer (MIBC). Genetically, MIBCs are categorized into t
Externí odkaz:
https://doaj.org/article/556cb3d5be2040e7a0f5529044b4d406
Autor:
Savannah R. Brown, Emilie E. Vomhof-DeKrey, Sarmad Al-Marsoummi, Nicholas D. Brown, Kole Hermanson, Marc D. Basson
Publikováno v:
Cancers, Vol 15, Iss 23, p 5658 (2023)
Triple-negative breast cancer (TNBC) has a poor prognosis and no targeted therapy for treatment. The Schlafen gene family, particularly SLFN12, critically mediates TNBC biology. Higher expression of SLFN12 correlates with decreased TNBC viability and
Externí odkaz:
https://doaj.org/article/48082bf7514c47778c4a8bb7e1cc67f1
Autor:
Sarmad Al-Marsoummi, Aaron A. Mehus, Swojani Shrestha, Rayna Rice, Brooke Rossow, Seema Somji, Scott H. Garrett, Donald A. Sens
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 17, p 13303 (2023)
Kidney progenitor cells, although rare and dispersed, play a key role in the repair of renal tubules after acute kidney damage. However, understanding these cells has been challenging due to the limited access to primary renal tissues and the absence
Externí odkaz:
https://doaj.org/article/3836153caed54bb1a6ee6d2df3da41e6
Autor:
Aaron A. Mehus, Madison Jones, Mason Trahan, Kaija Kinnunen, Kaitlyn Berwald, Becker Lindner, Sarmad Al-Marsoummi, Xu Dong Zhou, Scott H. Garrett, Donald A. Sens, Mary Ann Sens, Seema Somji
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 11, p 9149 (2023)
Urothelial cancer (UC) is a common malignancy and its development is associated with arsenic exposure. Around 25% of diagnosed UC cases are muscle invasive (MIUC) and are frequently associated with squamous differentiation. These patients commonly de
Externí odkaz:
https://doaj.org/article/05150f2609674a0e933c9a11c617f052
Autor:
Sandeep K. Singhal, Sarmad Al-Marsoummi, Emilie E. Vomhof-DeKrey, Bo Lauckner, Trysten Beyer, Marc D. Basson
Publikováno v:
Cancers, Vol 15, Iss 2, p 402 (2023)
The Schlafen 12 (SLFN12) protein regulates triple-negative breast cancer (TNBC) growth, differentiation, and proliferation. SLFN12 mRNA expression strongly correlates with TNBC patient survival. We sought to explore SLFN12 overexpression effects on i
Externí odkaz:
https://doaj.org/article/b4e549ce55234315b3fe98a67df03b16
Publikováno v:
Cellular Physiology and Biochemistry, Vol 53, Iss 6, Pp 999-1014 (2019)
Externí odkaz:
https://doaj.org/article/8ba1e0a96de04ed8abd91d868563d78f
Autor:
Marc D. Basson, Qinggang Wang, Lakshmi S. Chaturvedi, Shyam More, Emilie E. Vomhof-DeKrey, Sarmad Al-Marsoummi, Kelian Sun, Leslie A. Kuhn, Pavlo Kovalenko, Matti Kiupel
Publikováno v:
Cellular Physiology and Biochemistry, Vol 48, Iss 3, Pp 1274-1290 (2018)
Background/Aims: Human enterocytic differentiation is altered during development, fasting, adaptation, and bariatric surgery, but its intracellular control remains unclear. We hypothesized that Schlafen 12 (SLFN12) regulates enterocyte differentiatio
Externí odkaz:
https://doaj.org/article/9a0fd7ac3dd445bbbe7785fd1aa2086f
Publikováno v:
Cells, Vol 10, Iss 9, p 2238 (2021)
Schlafens (SLFN) are a family of genes widely expressed in mammals, including humans and rodents. These intriguing proteins play different roles in regulating cell proliferation, cell differentiation, immune cell growth and maturation, and inhibiting
Externí odkaz:
https://doaj.org/article/e56bc5ae8ce94fd8a267db44027edf8a
Autor:
Sarmad Al-Marsoummi, Jonathan Pacella, Kaylee Dockter, Matthew Soderberg, Sandeep K. Singhal, Emilie E. Vomhof-DeKrey, Marc D. Basson
Publikováno v:
Cancers, Vol 12, Iss 10, p 2738 (2020)
Schlafen 12 (SLFN12) is an intermediate human Schlafen that induces differentiation in enterocytes, prostate, and breast cancer. We hypothesized that SLFN12 influences lung cancer biology. We investigated survival differences in high versus low SLFN1
Externí odkaz:
https://doaj.org/article/bcbd5c7957b04568a081b50a675179f1
Publikováno v:
Cancer Genomics Proteomics
Background/Aim: Schlafen 12 (SLFN12) expression correlates with survival in triple negative breast cancer (TNBC). SLFN12 slows TNBC proliferation and induces TNBC differentiation, but whether SLFN12 affects the tumoral response to chemotherapy or rad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::515a2564adc0d3506e9ba36c7841ecec
https://europepmc.org/articles/PMC9016483/
https://europepmc.org/articles/PMC9016483/