Association of Seizure Foci and Location of Tau and Amyloid Deposition and Brain Atrophy in Patients With Alzheimer Disease and Seizures.

Autor: Lam AD; From the Department of Neurology (A.D.L., S.H., K.R.P., A.V., K.A.J.), Massachusetts General Hospital, Boston; Harvard Medical School (A.D.L., A.V., S.B., R.A. Sarkis, H.L.J., K.A.J., R.A. Sperling), Boston; Department of Radiology (E.G.T., D.V.M., H.L.J., K.A.J.), Massachusetts General Hospital, Boston; Department of Neurology (E.J.S.), Milford Regional Medical Center; Department of Neurology (S.B.), Beth Israel Deaconess Medical Center, Boston; and Department of Neurology (R.A.Sarkis, R.A.Sperling), Brigham and Women's Hospital, Boston, MA., Thibault EG; From the Department of Neurology (A.D.L., S.H., K.R.P., A.V., K.A.J.), Massachusetts General Hospital, Boston; Harvard Medical School (A.D.L., A.V., S.B., R.A. Sarkis, H.L.J., K.A.J., R.A. Sperling), Boston; Department of Radiology (E.G.T., D.V.M., H.L.J., K.A.J.), Massachusetts General Hospital, Boston; Department of Neurology (E.J.S.), Milford Regional Medical Center; Department of Neurology (S.B.), Beth Israel Deaconess Medical Center, Boston; and Department of Neurology (R.A.Sarkis, R.A.Sperling), Brigham and Women's Hospital, Boston, MA., Mayblyum DV; From the Department of Neurology (A.D.L., S.H., K.R.P., A.V., K.A.J.), Massachusetts General Hospital, Boston; Harvard Medical School (A.D.L., A.V., S.B., R.A. Sarkis, H.L.J., K.A.J., R.A. Sperling), Boston; Department of Radiology (E.G.T., D.V.M., H.L.J., K.A.J.), Massachusetts General Hospital, Boston; Department of Neurology (E.J.S.), Milford Regional Medical Center; Department of Neurology (S.B.), Beth Israel Deaconess Medical Center, Boston; and Department of Neurology (R.A.Sarkis, R.A.Sperling), Brigham and Women's Hospital, Boston, MA., Hsieh S; From the Department of Neurology (A.D.L., S.H., K.R.P., A.V., K.A.J.), Massachusetts General Hospital, Boston; Harvard Medical School (A.D.L., A.V., S.B., R.A. Sarkis, H.L.J., K.A.J., R.A. Sperling), Boston; Department of Radiology (E.G.T., D.V.M., H.L.J., K.A.J.), Massachusetts General Hospital, Boston; Department of Neurology (E.J.S.), Milford Regional Medical Center; Department of Neurology (S.B.), Beth Israel Deaconess Medical Center, Boston; and Department of Neurology (R.A.Sarkis, R.A.Sperling), Brigham and Women's Hospital, Boston, MA., Pellerin KR; From the Department of Neurology (A.D.L., S.H., K.R.P., A.V., K.A.J.), Massachusetts General Hospital, Boston; Harvard Medical School (A.D.L., A.V., S.B., R.A. Sarkis, H.L.J., K.A.J., R.A. Sperling), Boston; Department of Radiology (E.G.T., D.V.M., H.L.J., K.A.J.), Massachusetts General Hospital, Boston; Department of Neurology (E.J.S.), Milford Regional Medical Center; Department of Neurology (S.B.), Beth Israel Deaconess Medical Center, Boston; and Department of Neurology (R.A.Sarkis, R.A.Sperling), Brigham and Women's Hospital, Boston, MA., Sternberg EJ; From the Department of Neurology (A.D.L., S.H., K.R.P., A.V., K.A.J.), Massachusetts General Hospital, Boston; Harvard Medical School (A.D.L., A.V., S.B., R.A. Sarkis, H.L.J., K.A.J., R.A. Sperling), Boston; Department of Radiology (E.G.T., D.V.M., H.L.J., K.A.J.), Massachusetts General Hospital, Boston; Department of Neurology (E.J.S.), Milford Regional Medical Center; Department of Neurology (S.B.), Beth Israel Deaconess Medical Center, Boston; and Department of Neurology (R.A.Sarkis, R.A.Sperling), Brigham and Women's Hospital, Boston, MA., Viswanathan A; From the Department of Neurology (A.D.L., S.H., K.R.P., A.V., K.A.J.), Massachusetts General Hospital, Boston; Harvard Medical School (A.D.L., A.V., S.B., R.A. Sarkis, H.L.J., K.A.J., R.A. Sperling), Boston; Department of Radiology (E.G.T., D.V.M., H.L.J., K.A.J.), Massachusetts General Hospital, Boston; Department of Neurology (E.J.S.), Milford Regional Medical Center; Department of Neurology (S.B.), Beth Israel Deaconess Medical Center, Boston; and Department of Neurology (R.A.Sarkis, R.A.Sperling), Brigham and Women's Hospital, Boston, MA., Buss S; From the Department of Neurology (A.D.L., S.H., K.R.P., A.V., K.A.J.), Massachusetts General Hospital, Boston; Harvard Medical School (A.D.L., A.V., S.B., R.A. Sarkis, H.L.J., K.A.J., R.A. Sperling), Boston; Department of Radiology (E.G.T., D.V.M., H.L.J., K.A.J.), Massachusetts General Hospital, Boston; Department of Neurology (E.J.S.), Milford Regional Medical Center; Department of Neurology (S.B.), Beth Israel Deaconess Medical Center, Boston; and Department of Neurology (R.A.Sarkis, R.A.Sperling), Brigham and Women's Hospital, Boston, MA., Sarkis RA; From the Department of Neurology (A.D.L., S.H., K.R.P., A.V., K.A.J.), Massachusetts General Hospital, Boston; Harvard Medical School (A.D.L., A.V., S.B., R.A. Sarkis, H.L.J., K.A.J., R.A. Sperling), Boston; Department of Radiology (E.G.T., D.V.M., H.L.J., K.A.J.), Massachusetts General Hospital, Boston; Department of Neurology (E.J.S.), Milford Regional Medical Center; Department of Neurology (S.B.), Beth Israel Deaconess Medical Center, Boston; and Department of Neurology (R.A.Sarkis, R.A.Sperling), Brigham and Women's Hospital, Boston, MA., Jacobs HIL; From the Department of Neurology (A.D.L., S.H., K.R.P., A.V., K.A.J.), Massachusetts General Hospital, Boston; Harvard Medical School (A.D.L., A.V., S.B., R.A. Sarkis, H.L.J., K.A.J., R.A. Sperling), Boston; Department of Radiology (E.G.T., D.V.M., H.L.J., K.A.J.), Massachusetts General Hospital, Boston; Department of Neurology (E.J.S.), Milford Regional Medical Center; Department of Neurology (S.B.), Beth Israel Deaconess Medical Center, Boston; and Department of Neurology (R.A.Sarkis, R.A.Sperling), Brigham and Women's Hospital, Boston, MA., Johnson KA; From the Department of Neurology (A.D.L., S.H., K.R.P., A.V., K.A.J.), Massachusetts General Hospital, Boston; Harvard Medical School (A.D.L., A.V., S.B., R.A. Sarkis, H.L.J., K.A.J., R.A. Sperling), Boston; Department of Radiology (E.G.T., D.V.M., H.L.J., K.A.J.), Massachusetts General Hospital, Boston; Department of Neurology (E.J.S.), Milford Regional Medical Center; Department of Neurology (S.B.), Beth Israel Deaconess Medical Center, Boston; and Department of Neurology (R.A.Sarkis, R.A.Sperling), Brigham and Women's Hospital, Boston, MA., Sperling RA; From the Department of Neurology (A.D.L., S.H., K.R.P., A.V., K.A.J.), Massachusetts General Hospital, Boston; Harvard Medical School (A.D.L., A.V., S.B., R.A. Sarkis, H.L.J., K.A.J., R.A. Sperling), Boston; Department of Radiology (E.G.T., D.V.M., H.L.J., K.A.J.), Massachusetts General Hospital, Boston; Department of Neurology (E.J.S.), Milford Regional Medical Center; Department of Neurology (S.B.), Beth Israel Deaconess Medical Center, Boston; and Department of Neurology (R.A.Sarkis, R.A.Sperling), Brigham and Women's Hospital, Boston, MA.

Publikováno v: Neurology [Neurology] 2024 Nov 12; Vol. 103 (9), pp. e209920. Date of Electronic Publication: 2024 Sep 27.

Sleep functional connectivity, hyperexcitability, and cognition in Alzheimer's disease.

Autor: Moguilner SG; Department of Neurology, Harvard Medical School, Boston, Massachusetts, USA.; Department of Neurology, Massachusetts General Hospital, Boston, Massachusetts, USA., Berezuk C; Department of Neurology, Harvard Medical School, Boston, Massachusetts, USA.; Department of Neurology, Massachusetts General Hospital, Boston, Massachusetts, USA., Bender AC; Department of Neurology, Harvard Medical School, Boston, Massachusetts, USA.; Department of Neurology, Massachusetts General Hospital, Boston, Massachusetts, USA., Pellerin KR; Department of Neurology, Massachusetts General Hospital, Boston, Massachusetts, USA., Gomperts SN; Department of Neurology, Harvard Medical School, Boston, Massachusetts, USA.; Department of Neurology, Massachusetts General Hospital, Boston, Massachusetts, USA., Cash SS; Department of Neurology, Harvard Medical School, Boston, Massachusetts, USA.; Department of Neurology, Massachusetts General Hospital, Boston, Massachusetts, USA., Sarkis RA; Department of Neurology, Harvard Medical School, Boston, Massachusetts, USA.; Department of Neurology, Brigham and Women's Hospital, Boston, Massachusetts, USA., Lam AD; Department of Neurology, Harvard Medical School, Boston, Massachusetts, USA.; Department of Neurology, Massachusetts General Hospital, Boston, Massachusetts, USA.

Publikováno v: Alzheimer's & dementia : the journal of the Alzheimer's Association [Alzheimers Dement] 2024 Jun; Vol. 20 (6), pp. 4234-4249. Date of Electronic Publication: 2024 May 19.

Altered Sleep Microarchitecture and Cognitive Impairment in Patients With Temporal Lobe Epilepsy.

Autor: Bender AC; From the Epilepsy Service (A.C.B., A.J., K.R.P., S.M., S.S.C., A.D.L.), Department of Neurology, Massachusetts General Hospital & Harvard Medical School, Boston; and Epilepsy Service (R.A.S.), Department of Neurology, Brigham and Women's Hospital & Harvard Medical School, Boston, MA. acbender@partners.org., Jaleel A; From the Epilepsy Service (A.C.B., A.J., K.R.P., S.M., S.S.C., A.D.L.), Department of Neurology, Massachusetts General Hospital & Harvard Medical School, Boston; and Epilepsy Service (R.A.S.), Department of Neurology, Brigham and Women's Hospital & Harvard Medical School, Boston, MA., Pellerin KR; From the Epilepsy Service (A.C.B., A.J., K.R.P., S.M., S.S.C., A.D.L.), Department of Neurology, Massachusetts General Hospital & Harvard Medical School, Boston; and Epilepsy Service (R.A.S.), Department of Neurology, Brigham and Women's Hospital & Harvard Medical School, Boston, MA., Moguilner S; From the Epilepsy Service (A.C.B., A.J., K.R.P., S.M., S.S.C., A.D.L.), Department of Neurology, Massachusetts General Hospital & Harvard Medical School, Boston; and Epilepsy Service (R.A.S.), Department of Neurology, Brigham and Women's Hospital & Harvard Medical School, Boston, MA., Sarkis RA; From the Epilepsy Service (A.C.B., A.J., K.R.P., S.M., S.S.C., A.D.L.), Department of Neurology, Massachusetts General Hospital & Harvard Medical School, Boston; and Epilepsy Service (R.A.S.), Department of Neurology, Brigham and Women's Hospital & Harvard Medical School, Boston, MA., Cash SS; From the Epilepsy Service (A.C.B., A.J., K.R.P., S.M., S.S.C., A.D.L.), Department of Neurology, Massachusetts General Hospital & Harvard Medical School, Boston; and Epilepsy Service (R.A.S.), Department of Neurology, Brigham and Women's Hospital & Harvard Medical School, Boston, MA., Lam AD; From the Epilepsy Service (A.C.B., A.J., K.R.P., S.M., S.S.C., A.D.L.), Department of Neurology, Massachusetts General Hospital & Harvard Medical School, Boston; and Epilepsy Service (R.A.S.), Department of Neurology, Brigham and Women's Hospital & Harvard Medical School, Boston, MA.

Publikováno v: Neurology [Neurology] 2023 Dec 04; Vol. 101 (23), pp. e2376-e2387. Date of Electronic Publication: 2023 Dec 04.

Initial case series of a novel sensing deep brain stimulation device in drug-resistant epilepsy and consistent identification of alpha/beta oscillatory activity: A feasibility study.

Autor: Chua MMJ; Department of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA., Vissani M; Department of Neurosurgery, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA., Liu DD; Department of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA., Schaper FLWVJ; Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA., Warren AEL; Department of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA., Caston R; Department of Biomedical Engineering, University of Utah, Salt Lake City, Utah, USA.; Department of Neurosurgery, University of Utah, Salt Lake City, Utah, USA., Dworetzky BA; Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA., Bubrick EJ; Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA., Sarkis RA; Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA., Cosgrove GR; Department of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA., Rolston JD; Department of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.; Department of Biomedical Engineering, University of Utah, Salt Lake City, Utah, USA.; Department of Neurosurgery, University of Utah, Salt Lake City, Utah, USA.

Publikováno v: Epilepsia [Epilepsia] 2023 Oct; Vol. 64 (10), pp. 2586-2603. Date of Electronic Publication: 2023 Jul 28.

Interictal epileptiform discharges in Alzheimer's disease: prevalence, relevance, and controversies.

Autor: Lemus HN; Department of Neurology, Brigham and Women's Hospital, Boston, MA, United States., Sarkis RA; Department of Neurology, Brigham and Women's Hospital, Boston, MA, United States.

Publikováno v: Frontiers in neurology [Front Neurol] 2023 Sep 21; Vol. 14, pp. 1261136. Date of Electronic Publication: 2023 Sep 21 (Print Publication: 2023).