Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Sarkis Barret Kalindjian"'
Autor:
Jeremy G. Vinter, I. M. Mcdonald, Sarkis Barret Kalindjian, Caroline M. R. Low, I. M. Buck, David John Dunstone, Jonathan Michael Richard Davies, Michael John Pether, Martin L. Hudson, Tozer Matthew John, Katherine Isobel Mary Steel
Publikováno v:
Journal of Medicinal Chemistry. 39:1806-1815
A series of potent and selective cholecystokinin-B/gastrin receptor antagonists based on the dibenzobicyclo[2.2.2]octane (BCO) skeleton which have recently been described were found to show species-dependent behavior when examined in rat and dog mode
Autor:
Katherine Isobel Mary Steel, Martin L. Hudson, David John Dunstone, Ildiko Maria Buck, Iain Mair Mcdonald, Caroline M. R. Low, J. R. Cushnir, Sarkis Barret Kalindjian, Matthew J. Tozer, Michael John Pether
Publikováno v:
Journal of Medicinal Chemistry. 38:4294-4302
We have recently described a novel series of nonpeptidic cholecystokinin-B (CCK B )/gastrin receptor antagonists based on a dibenzobicyclo[2.2.2]octane skeleton. We wish now to report on compounds arising out of our earlier work which have substantia
Autor:
David John Dunstone, J. R. Cushnir, Sarkis Barret Kalindjian, Martin L. Hudson, Ildiko Maria Buck, Caroline M. R. Low, Matthew J. Tozer, Michael John Pether, Iain Mair Mcdonald, Katherine Isobel Mary Steel
Publikováno v:
ChemInform. 27
We have recently described a novel series of nonpeptidic cholecystokinin-B (CCK B )/gastrin receptor antagonists based on a dibenzobicyclo[2.2.2]octane skeleton. We wish now to report on compounds arising out of our earlier work which have substantia
Publikováno v:
ChemInform. 27
Autor:
I. M. Buck, D. J. Dunstone, M. J. Pether, Sarkis Barret Kalindjian, Trushar Adatia, John Spencer, Alan Bashall, Elaine Anne Harper, C. Austin, I. M. Mcdonald, Caroline M. R. Low, Eric P. Griffin, Ian D. Linney, P. T. Wright, R. A. D. Hull
Publikováno v:
Journal of medicinal chemistry. 49(7)
A series of 1,3,4-benzotriazepine-based CCK(2) antagonists have been devised by consideration of the structural features that govern CCK receptor affinity and the receptor subtype selectivity of 1,4-benzodiazepine-based CCK(2) antagonists. In contras
Autor:
C. M. R. Low, Katherine Isobel Mary Steel, I. M. Buck, David John Dunstone, I. M. Mcdonald, Michael J. Bodkin, Michael John Pether, Sarkis Barret Kalindjian
Publikováno v:
Journal of Medicinal Chemistry. 37:3671-3673
Autor:
David John Dunstone, Sarkis Barret Kalindjian, Tozer Matthew John, Jeremy G. Vinter, Katherine Isobel Mary Steel, I. M. Mcdonald, C. M. R. Low, Ian D. Linney, Michael John Pether
Publikováno v:
Journal of medicinal chemistry. 43(19)
A novel series of nonpeptide CCK(2) receptor antagonists has been prepared, in which 2,7-dioxo-2,3,4,5,6,7-hexahydro-1H-benzo[h][1, 4]diazonine (5) was used as a chemical template. This uncommon ring system was obtained in a highly substituted form a