Zobrazeno 1 - 10
of 79
pro vyhledávání: '"Sarkis, Sarkis"'
Autor:
Anna Gutowska, Sarkis Sarkis, Mohammad Arif Rahman, Katherine C. Goldfarbmuren, Ramona Moles, Massimiliano Bissa, Melvin Doster, Robyn Washington-Parks, Katherine McKinnon, Isabela Silva de Castro, Luca Schifanella, Genoveffa Franchini, Cynthia A. Pise-Masison
Publikováno v:
Pathogens, Vol 13, Iss 4, p 292 (2024)
The transient depletion of monocytes alone prior to exposure of macaques to HTLV-1 enhances both HTLV-1WT (wild type) and HTLV-1p12KO (Orf-1 knockout) infectivity, but seroconversion to either virus is not sustained over time, suggesting a progressiv
Externí odkaz:
https://doaj.org/article/244978497a084b2aa6b766b25236667b
Autor:
Massimiliano Bissa, Sohyoung Kim, Veronica Galli, Slim Fourati, Sarkis Sarkis, Anush Arakelyan, Isabela Silva de Castro, Mohammad Arif Rahman, Saori Fujiwara, Monica Vaccari, Jeffrey A. Tomalka, James D. Stamos, Luca Schifanella, Giacomo Gorini, Ramona Moles, Anna Gutowska, Guido Ferrari, Alexei Lobanov, David C. Montefiori, George W. Nelson, Margaret C. Cam, Marita Chakhtoura, Elias K. Haddad, Melvin N. Doster, Katherine McKinnon, Sophia Brown, David J. Venzon, Hyoyoung Choo-Wosoba, Matthew W. Breed, Kristin E. Killoran, Joshua Kramer, Leonid Margolis, Rafick P. Sekaly, Gordon L. Hager, Genoveffa Franchini
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
HIV vaccine development can be aided by knowledge of correlates of protection. Here the authors identify engagement and reprogramming of tolerogenic CD14+ myeloid cells mediating a spatiotemporal balance of pro- and anti-inflammatory responses, as co
Externí odkaz:
https://doaj.org/article/f273918f9336463f8dcd9cedb0b73046
Akademický článek
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Autor:
Mohammad Arif Rahman, Manuel Becerra-Flores, Yury Patskovsky, Isabela Silva de Castro, Massimiliano Bissa, Shraddha Basu, Xiaoying Shen, LaTonya D. Williams, Sarkis Sarkis, Kombo F. N’guessan, Celia LaBranche, Georgia D. Tomaras, Pyone Pyone Aye, Ronald Veazey, Dominic Paquin-Proulx, Mangala Rao, Genoveffa Franchini, Timothy Cardozo
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionAn efficacious HIV vaccine will need to elicit a complex package of innate, humoral, and cellular immune responses. This complex package of responses to vaccine candidates has been studied and yielded important results, yet it has been a
Externí odkaz:
https://doaj.org/article/f271626acd674386b239c0823d800dfb
Autor:
Massimiliano Bissa, Veronica Galli, Luca Schifanella, Monica Vaccari, Mohammad Arif Rahman, Giacomo Gorini, Nicolò Binello, Sarkis Sarkis, Anna Gutowska, Isabela Silva de Castro, Melvin N. Doster, Ramona Moles, Guido Ferrari, Xiaoying Shen, Georgia D. Tomaras, David C. Montefiori, Kombo F. N’guessan, Dominic Paquin-Proulx, Pamela A. Kozlowski, David J. Venzon, Hyoyoung Choo-Wosoba, Matthew W. Breed, Joshua Kramer, Genoveffa Franchini
Publikováno v:
Vaccines, Vol 11, Iss 11, p 1662 (2023)
At the heart of the DNA/ALVAC/gp120/alum vaccine’s efficacy in the absence of neutralizing antibodies is a delicate balance of pro- and anti-inflammatory immune responses that effectively decreases the risk of SIVmac251 acquisition in macaques. Vac
Externí odkaz:
https://doaj.org/article/c79e712a0eef406bace853be5af64634
Akademický článek
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Autor:
Anna Gutowska, Katherine McKinnon, Sarkis Sarkis, Melvin N. Doster, Massimiliano Bissa, Ramona Moles, James D. Stamos, Mohammad Arif Rahman, Robyn Washington-Parks, David Davis, Robert Yarchoan, Genoveffa Franchini, Cynthia A. Pise-Masison
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
Human T cell leukemia virus type 1 (HTLV-1) persists in the host despite a vigorous immune response that includes cytotoxic T cells (CTL) and natural killer (NK) cells, suggesting the virus has developed effective mechanisms to counteract host immune
Externí odkaz:
https://doaj.org/article/71d7e6b3d5f24250b9a47b2a88566aca
Autor:
Sarkis, Sarkis
La paraparésie spastique tropicale ou la myélopathie associée à HTLV-1 (TSP/HAM) est une maladie neurologique chronique caractérisée par le développement de paralysies spastiques des membres inférieurs et de déficits sensoriels divers. Une i
Externí odkaz:
http://www.theses.fr/2013MON20015/document
Autor:
Silva de Castro, Isabela, Gorini, Giacomo, Mason, Rosemarie, Gorman, Jason, Bissa, Massimiliano, Rahman, Mohammad A., Arakelyan, Anush, Kalisz, Irene, Whitney, Stephen, Becerra-Flores, Manuel, Ni, Eric, Peachman, Kristina, Trinh, Hung V., Read, Michael, Liu, Mei-Hue, Van Ryk, Donald, Paquin-Proulx, Dominic, Shubin, Zhanna, Tuyishime, Marina, Peele, Jennifer, Ahmadi, Mohammed S., Verardi, Raffaello, Hill, Juliane, Beddall, Margaret, Nguyen, Richard, Stamos, James D., Fujikawa, Dai, Min, Susie, Schifanella, Luca, Vaccari, Monica, Galli, Veronica, Doster, Melvin N., Liyanage, Namal P.M., Sarkis, Sarkis, Caccuri, Francesca, LaBranche, Celia, Montefiori, David C., Tomaras, Georgia D., Shen, Xiaoying, Rosati, Margherita, Felber, Barbara K., Pavlakis, George N., Venzon, David J., Magnanelli, William, Breed, Matthew, Kramer, Josh, Keele, Brandon F., Eller, Michael A., Cicala, Claudia, Arthos, James, Ferrari, Guido, Margolis, Leonid, Robert-Guroff, Marjorie, Kwong, Peter D., Roederer, Mario, Rao, Mangala, Cardozo, Timothy J., Franchini, Genoveffa
Publikováno v:
In iScience 19 February 2021 24(2)
Autor:
Ramona Moles, Sarkis Sarkis, Veronica Galli, Maria Omsland, Maria Artesi, Massimiliano Bissa, Katherine McKinnon, Sophia Brown, Vincent Hahaut, Robyn Washington-Parks, Joshua Welsh, David J Venzon, Anna Gutowska, Melvin N Doster, Matthew W Breed, Kristin E Killoran, Joshua Kramer, Jennifer Jones, Marcin Moniuszko, Anne Van den Broeke, Cynthia A Pise-Masison, Genoveffa Franchini
Publikováno v:
PLoS Pathogens, Vol 18, Iss 4, p e1010416 (2022)
We investigated the impact of monocytes, NK cells, and CD8+ T-cells in primary HTLV-1 infection by depleting cell subsets and exposing macaques to either HTLV-1 wild type (HTLV-1WT) or to the HTLV-1p12KO mutant unable to infect replete animals due to
Externí odkaz:
https://doaj.org/article/615eebba068a408f8b018f2bc095086a