Zobrazeno 1 - 10
of 122
pro vyhledávání: '"Sarki A. Abdulkadir"'
Autor:
Sukanya Panja, Mihai Ioan Truica, Christina Y. Yu, Vamshi Saggurthi, Michael W. Craige, Katie Whitehead, Mayra V. Tuiche, Aymen Al-Saadi, Riddhi Vyas, Shridar Ganesan, Suril Gohel, Frederick Coffman, James S. Parrott, Songhua Quan, Shantenu Jha, Isaac Kim, Edward Schaeffer, Vishal Kothari, Sarki A. Abdulkadir, Antonina Mitrofanova
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-24 (2024)
Abstract Heterogeneous response to Enzalutamide, a second-generation androgen receptor signaling inhibitor, is a central problem in castration-resistant prostate cancer (CRPC) management. Genome-wide systems investigation of mechanisms that govern En
Externí odkaz:
https://doaj.org/article/f6960f68361b40e18d04bcb6422ccba2
Autor:
Zachary Richards, Tara McCray, Joseph Marsili, Morgan L. Zenner, Jacob T. Manlucu, Jason Garcia, Andre Kajdacsy-Balla, Marcus Murray, Cindy Voisine, Adam B. Murphy, Sarki A. Abdulkadir, Gail S. Prins, Larisa Nonn
Publikováno v:
iScience, Vol 12, Iss , Pp 304-317 (2019)
Summary: The fibromuscular stroma of the prostate regulates normal epithelial differentiation and contributes to carcinogenesis in vivo. We developed and characterized a human 3D prostate organoid co-culture model that incorporates prostate stroma. P
Externí odkaz:
https://doaj.org/article/a102fb12710c44299201cd66c7bc62a0
Autor:
Jonathan F. Anker, Anum F. Naseem, Hanlin Mok, Anthony J. Schaeffer, Sarki A. Abdulkadir, Praveen Thumbikat
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
CP1 is an uropathogenic Escherichia coli previously shown to promote inflammation and progression to prostate cancer. Here the authors show that in the context of a fully developed prostate cancer, CP1 promotes T cell infiltration into the tumour and
Externí odkaz:
https://doaj.org/article/3bf73253b2574b74bdc59f395c2f2af5
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
Epidemiological and preclinical data suggest that antioxidants are protective against prostate cancer whose pathogenesis has been linked to oxidative stress. However, the selenium and vitamin E Cancer Prevention Trial (SELECT), found no efficacy for
Externí odkaz:
https://doaj.org/article/9db76ba213df460ab2218b279c41967d
Autor:
Young A. Yoo, Meejeon Roh, Anum F. Naseem, Barbara Lysy, Mohamed M. Desouki, Kenji Unno, Sarki A. Abdulkadir
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
The polycomb repressor protein Bmi1 has a role in self-renewal and tumorigenesis. Here, the authors use lineage tracing to show that Bmi-expressing cells are a distinct population of cells, primarily found in the luminal compartment, which is castrat
Externí odkaz:
https://doaj.org/article/723bb9021c454c7c895f31deacc88d0a
Autor:
Dikshat Gopal Gupta, Neelam Varma, Sreejesh Sreedharanunni, Sarki Abba Abdulkadir, Shano Naseem, Man Updesh Singh Sachdeva, Jogeshwar Binota, Parveen Bose, Pankaj Malhotra, Alka Khadwal, Subhash Varma
Publikováno v:
British Journal of Cancer.
Autor:
Franklin W. Huang, Joshua D. Campbell, Garrett M. Frampton, Matthew Meyerson, Elad Ziv, Sarki A. Abdulkadir, Paz Polak, Daphnee Piou, Jian Carrot-Zhang, Eejung Kim, Justin Newberg, Zachary R. Chalmers, Hanbing Song, Yusuke Koga
Associations of recurrent deletion events of selected genes with Gleason score and race in TCGA and AAPC cohorts. Left: Amplification frequencies were associated with race and Gleason score while controlling for age using samples from TCGA and AAPC c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5af85e2d20ba0e12feba814187b7b25
https://doi.org/10.1158/1078-0432.22476986
https://doi.org/10.1158/1078-0432.22476986
Autor:
Sarki A. Abdulkadir, Yue Zhao, Himisha Beltran, Sheng-Yu Ku, Young A. Yoo, Huiying Han, Vinay Sagar, Hanlin Mok, Barbara Lysy, Yara Rodriguez, Rajita Vatapalli, Sahithi Pamarthy, Zachary R. Chalmers, Kenji Unno
Neuroendocrine prostate cancer (NEPC) is an aggressive subtype of prostate cancer with poor prognosis, and there is a critical need for novel therapeutic approaches. NEPC is associated with molecular perturbation of several pathways, including amplif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4bb69c104c9b6c576d41fdd38f4bbd5e
https://doi.org/10.1158/0008-5472.c.6512901.v1
https://doi.org/10.1158/0008-5472.c.6512901.v1
Autor:
Sarki A. Abdulkadir, Huiying Han, Maha Hussain, Barbara Lysy, Jindan Yu, Vinay Sagar, Rajita Vatapalli, Young A. Yoo, Zachary R. Chalmers, Mihai I. Truica, Kenji Unno, Yara Rodríguez
Supplementary Table from A Genome-Wide CRISPR Activation Screen Identifies PRRX2 as a Regulator of Enzalutamide Resistance in Prostate Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c18cbe8dcd1d09b2c8163ac02fea55e
https://doi.org/10.1158/0008-5472.22430805.v1
https://doi.org/10.1158/0008-5472.22430805.v1
Autor:
Franklin W. Huang, Joshua D. Campbell, Garrett M. Frampton, Matthew Meyerson, Elad Ziv, Sarki A. Abdulkadir, Paz Polak, Daphnee Piou, Jian Carrot-Zhang, Eejung Kim, Justin Newberg, Zachary R. Chalmers, Hanbing Song, Yusuke Koga
Purpose:African American (AFR) men have the highest mortality rate from prostate cancer (PCa) compared with men of other racial/ancestral groups. Differences in the spectrum of somatic genome alterations in tumors between AFR men and other population
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::100dbbd0efa4c82447c418f730ef7ec6
https://doi.org/10.1158/1078-0432.c.6529544
https://doi.org/10.1158/1078-0432.c.6529544