Molecular Docking, Pharmacokinetic and Molecular Simulation Analysis of Novel Mono-Carbonyl Curcumin Analogs as L858R/T790M/C797S Mutant EGFR Inhibitors.

Autor: Bhandari SV; Department of Pharmaceutical Chemistry, A.I.S.S.M.S College of Pharmacy, near RTO, Kennedy Road, Pune, 411001, Maharashtra, India., Kuthe PV; Department of Pharmaceutical Chemistry, A.I.S.S.M.S College of Pharmacy, near RTO, Kennedy Road, Pune, 411001, Maharashtra, India., Patil SM; Department of Pharmaceutical Chemistry, A.I.S.S.M.S College of Pharmacy, near RTO, Kennedy Road, Pune, 411001, Maharashtra, India., Nagras OG; Department of Pharmaceutical Chemistry, A.I.S.S.M.S College of Pharmacy, near RTO, Kennedy Road, Pune, 411001, Maharashtra, India., Sarkate AP; Department of Chemical Technology, Dr. Babasaheb Ambedkar Marathwada University, Aurangabad, 431004, Maharashtra, India., Chaudhari SY; Department of Pharmaceutical Chemistry, Modern College of Pharmacy, Yamunanagar, Sector 21, Nigdi, Pune, 411044, Maharashtra, India., Surve SV; Department of Pharmaceutical Chemistry, A.I.S.S.M.S College of Pharmacy, near RTO, Kennedy Road, Pune, 411001, Maharashtra, India.

Publikováno v: Chemistry & biodiversity [Chem Biodivers] 2023 Nov; Vol. 20 (11), pp. e202301081. Date of Electronic Publication: 2023 Oct 26.

Design, synthesis, and biological evaluation of novel quinoline derivatives as small molecule mutant EGFR inhibitors targeting resistance in NSCLC: In vitro screening and ADME predictions.

Autor: Kardile RA; Department of Chemistry, Radhabai Kale Mahila Mahavidyalaya, Ahmednagar, 414001, Maharashtra, India., Sarkate AP; Department of Chemical Technology, Dr. Babasaheb Ambedkar Marathwada University, Aurangabad, 431004, Maharashtra, India., Lokwani DK; Rajarshi Shahu College of Pharmacy, Buldhana, 443001, Maharashtra, India., Tiwari SV; Shri Ramkrishna Paramhans College of Pharmacy, Hasnapur, Parbhani, 431401, Maharashtra, India., Azad R; Department of Animal Biology, University of Hyderabad, Hyderabad, 500046, India., Thopate SR; Department of Chemistry, Radhabai Kale Mahila Mahavidyalaya, Ahmednagar, 414001, Maharashtra, India. Electronic address: srthopate@gmail.com.

Publikováno v: European journal of medicinal chemistry [Eur J Med Chem] 2023 Jan 05; Vol. 245 (Pt 1), pp. 114889. Date of Electronic Publication: 2022 Oct 29.

Explorations of novel pyridine-pyrimidine hybrid phosphonate derivatives as aurora kinase inhibitors.

Autor: Tiwari SV; Department of Pharmaceutical Chemistry, Durgamata Institute of Pharmacy, Dharmapuri, Parbhani 431401, Maharashtra, India. Electronic address: shailee2010@gmail.com., Sarkate AP; Department of Chemical Technology, Dr. Babasaheb Ambedkar Marathwada University, Aurangabad 431 004, Maharashtra, India., Lokwani DK; Rajarshi Shahu College of Pharmacy, Buldana 443001, Maharashtra, India., Pansare DN; Department of Chemistry, Deogiri College, Station Road, Aurangabad 431 005, MS, India., Gattani SG; School of Pharmacy, S.R.T.M. University, Nanded 431006, Maharashtra, India., Sheaikh SS; Department of Pharmaceutical Chemistry, Durgamata Institute of Pharmacy, Dharmapuri, Parbhani 431401, Maharashtra, India., Jain SP; Rajarshi Shahu College of Pharmacy, Buldana 443001, Maharashtra, India., Bhandari SV; Department of Pharmaceutical Chemistry, AISSMS College of Pharmacy, Near RTO, Kennedy Road, Pune 411001, Maharashtra, India.

Publikováno v: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2022 Jul 01; Vol. 67, pp. 128747. Date of Electronic Publication: 2022 Apr 26.

Design and synthesis of novel conformationally constrained 7,12-dihydrodibenzo[b,h][1,6] naphthyridine and 7H-Chromeno[3,2-c] quinoline derivatives as topoisomerase I inhibitors: In vitro screening, molecular docking and ADME predictions.

Autor: Kardile RA; Department of Chemistry, Ahmednagar College, Ahmednagar 414001, Maharashtra, India., Sarkate AP; Department of Chemical Technology, Dr. Babasaheb Ambedkar Marathwada University, Aurangabad 431004, Maharashtra, India., Borude AS; Department of Chemistry, Ahmednagar College, Ahmednagar 414001, Maharashtra, India., Mane RS; Department of Chemistry, Dr. S. D. D. Arts College and Commerce and Science College, Wada 421303, Maharashtra, India., Lokwani DK; Department of Pharmaceutical Chemistry, R. C. Patel Institute of Pharmaceutical Education & Research, Shirpur 425405, Maharashtra, India., Tiwari SV; Department of Pharmaceutical Chemistry, Durgamata Institute of Pharmacy, Dharmapuri, Parbhani 431401, Maharashtra, India., Azad R; Department of Animal Biology, University of Hyderabad, Hyderabad 500046, India., Burra PVLS; Department of Biotechnology, KLEF University, Vaddeswaram 522502, Andhra Pradesh, India., Thopate SR; Department of Chemistry, S. S. G. M. College, Kopargaon 423601, Maharashtra, India. Electronic address: srthopate@gmail.com.

Publikováno v: Bioorganic chemistry [Bioorg Chem] 2021 Oct; Vol. 115, pp. 105174. Date of Electronic Publication: 2021 Jul 16.

One pot synthesis, in silico study and evaluation of some novel flavonoids as potent topoisomerase II inhibitors.

Autor: Sarkate AP; Department of Chemical Technology, Dr. Babasaheb Ambedkar Marathwada University, Aurangabad 431 004, Maharashtra, India. Electronic address: dbsaniket09@gmail.com., Dofe VS; Department of Chemistry, Deogiri College, Aurangabad 431 005, Maharashtra, India., Tiwari SV; Department of Pharmaceutical Chemistry, Durgamata Institute of Pharmacy, Dharmapuri, Parbhani 431401, Maharashtra, India., Lokwani DK; Department of Pharmaceutical Chemistry, R. C. Patel Institute of Pharmaceutical Education & Research, Shirpur 425405, Maharashtra, India. Electronic address: dklokwani@gmail.com., Karnik KS; Department of Chemical Technology, Dr. Babasaheb Ambedkar Marathwada University, Aurangabad 431 004, Maharashtra, India., Kamble DD; Department of Chemical Technology, Dr. Babasaheb Ambedkar Marathwada University, Aurangabad 431 004, Maharashtra, India., Ansari MHSH; Department of Chemical Technology, Dr. Babasaheb Ambedkar Marathwada University, Aurangabad 431 004, Maharashtra, India., Dodamani S; Dr. Prabhakar Kore Basic Science Research Center, KLE Academy of Higher Education and Research, Nehru Nagar, Belagavi 590010, Karnataka, India., Jalalpure SS; Dr. Prabhakar Kore Basic Science Research Center, KLE Academy of Higher Education and Research, Nehru Nagar, Belagavi 590010, Karnataka, India; KLE College of Pharmacy, KLE Academy of Higher Education and Research, Nehru Nagar, Belagavi 590010, Karnataka, India., Sangshetti JN; Y. B. Chavan College of Pharmacy, Aurangabad 431004, Maharashtra, India., Azad R; Department of Animal Biology, University of Hyderabad, Hyderabad 500046, India., Burra PVLS; Department of Biotechnology, KLEF University, Vaddeswaram 522502, AP, India., Bhandari SV; Department of Pharmaceutical Chemistry, AISSMS College of Pharmacy, Near RTO, Kennedy Road, Pune 411001, Maharashtra, India.

Publikováno v: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2021 May 15; Vol. 40, pp. 127916. Date of Electronic Publication: 2021 Mar 06.