Zobrazeno 1 - 10
of 101
pro vyhledávání: '"Sarkar M. A. Kawsar"'
Publikováno v:
Current Chemistry Letters, Vol 13, Iss 1, Pp 1-14 (2024)
Methyl α-D-mannopyranoside (MAM) is a naturally occurring carbohydrate derivative that has gained attention in drug discovery due to its potential therapeutic applications, particularly as an antifungal agent. In this study, we employed a computatio
Externí odkaz:
https://doaj.org/article/0e34d861485d478a9e17ba8fe14cc82f
Autor:
Aziz Arzine, Hanine Hadni, Khalid Boujdi, Khalid Chebbac, Najoua Barghady, Yassine Rhazi, Mohammed Chalkha, Asmae Nakkabi, Karim Chkirate, Joel T. Mague, Sarkar M. A. Kawsar, Ghali Al Houari, Mohammed M. Alanazi, Mohamed El Yazidi
Publikováno v:
Molecules, Vol 29, Iss 14, p 3366 (2024)
This work describes the synthesis, characterization, and in vitro and in silico evaluation of the biological activity of new functionalized isoxazole derivatives. The structures of all new compounds were analyzed by IR and NMR spectroscopy. The struc
Externí odkaz:
https://doaj.org/article/707089c6d0b84bc892426f840eb639a9
Autor:
Yuki Fujii, Kenichi Kamata, Marco Gerdol, Imtiaj Hasan, Sultana Rajia, Sarkar M. A. Kawsar, Somrita Padma, Bishnu Pada Chatterjee, Mayuka Ohkawa, Ryuya Ishiwata, Suzuna Yoshimoto, Masao Yamada, Namiho Matsuzaki, Keita Yamamoto, Yuka Niimi, Nobumitsu Miyanishi, Masamitsu Konno, Alberto Pallavicini, Tatsuya Kawasaki, Yukiko Ogawa, Yasuhiro Ozeki, Hideaki Fujita
Publikováno v:
Marine Drugs, Vol 22, Iss 6, p 269 (2024)
SeviL, a galactoside-binding lectin previously isolated from the mussel Mytilisepta virgata, was demonstrated to trigger apoptosis in HeLa ovarian cancer cells. Here, we show that this lectin can promote the polarization of macrophage cell lines towa
Externí odkaz:
https://doaj.org/article/d795b091223f4f63b90d83a4a294f0ef
Autor:
Antonella Messore, Paolo Malune, Elisa Patacchini, Valentina Noemi Madia, Davide Ialongo, Merve Arpacioglu, Aurora Albano, Giuseppe Ruggieri, Francesco Saccoliti, Luigi Scipione, Enzo Tramontano, Serena Canton, Angela Corona, Sante Scognamiglio, Annalaura Paulis, Mustapha Suleiman, Helmi Mohammed Al-Maqtari, Fatma Mohamed A. Abid, Sarkar M. A. Kawsar, Murugesan Sankaranarayanan, Roberto Di Santo, Francesca Esposito, Roberta Costi
Publikováno v:
Pharmaceuticals, Vol 17, Iss 5, p 650 (2024)
It has been more than four years since the first report of SARS-CoV-2, and humankind has experienced a pandemic with an unprecedented impact. Moreover, the new variants have made the situation even worse. Among viral enzymes, the SARS-CoV-2 main prot
Externí odkaz:
https://doaj.org/article/33897d42e8a5438eb1decd73c9215d74
Autor:
Sarkar M. A. Kawsar, Mohammed A. Hosen, Youness El Bakri, Sajjad Ahmad, Sopi T. Affi, Souraya Goumri-Said
Publikováno v:
Arab Journal of Basic and Applied Sciences, Vol 29, Iss 1, Pp 99-112 (2022)
Carbohydrates derivatives played an important and vital role in a large part to design new potential drug against various pathogens, in medicinal chemistry. Also, monosaccharide derivatives are very useful in biological chemistry because monosacchari
Externí odkaz:
https://doaj.org/article/4a5bb03907c143018540b7a5af4e8d53
Autor:
Sabina Akter, Bader Y. Alhatlani, Emad M. Abdallah, Supriyo Saha, Jannatul Ferdous, Md Emdad Hossain, Ferdausi Ali, Sarkar M. A. Kawsar
Publikováno v:
Molecules, Vol 28, Iss 24, p 8001 (2023)
The pursuit of innovative combinations for the development of novel antimicrobial and antiviral medications has garnered worldwide interest among scientists in recent times. Monosaccharides and their glycosides, such as methyl α-d-mannopyranoside de
Externí odkaz:
https://doaj.org/article/25dae70a7bba4ac3967f7afaac045248
Autor:
Mebarka Ouassaf, Lotfi Bourougaa, Samiah Hamad Al-Mijalli, Emad M. Abdallah, Ajmal R. Bhat, Sarkar M. A. Kawsar
Publikováno v:
Molecules, Vol 28, Iss 24, p 8074 (2023)
Marine compounds constitute a diverse and invaluable resource for the discovery of bioactive substances with promising applications in the pharmaceutical development of anti-inflammatory and antibacterial agents. In this study, a comprehensive method
Externí odkaz:
https://doaj.org/article/93385c9529cb46abbcb36fed709f09d3
Publikováno v:
Journal of Taibah University for Science, Vol 18, Iss 1 (2024)
Multiple diseases are treated with carbohydrate-based medicinal products worldwide. Direct regioselective acylation of methyl α-D-mannopyranoside (MDMP) derivatives 2-6 afforded from the 6-O-butyryl derivative. This isolated 6-O-derivative was conve
Externí odkaz:
https://doaj.org/article/911bc0e1f22146f3b24e7ce936921287
Autor:
Mustapha Suleiman, Faisal A. Almalki, Taibi Ben Hadda, Sarkar M. A. Kawsar, Subhash Chander, Sankaranarayanan Murugesan, Ajmal R. Bhat, Andrey Bogoyavlenskiy, Joazaizulfazli Jamalis
Publikováno v:
Pharmaceuticals, Vol 16, Iss 11, p 1538 (2023)
The human immunodeficiency virus (HIV) is the primary cause of acquired immune deficiency syndrome (AIDS), one of the deadliest pandemic diseases. Various mechanisms and procedures have been pursued to synthesise several anti-HIV agents, but due to t
Externí odkaz:
https://doaj.org/article/559cdffea7a54480bdf5f6c7a2dd6f37
Publikováno v:
Molecules, Vol 28, Iss 18, p 6678 (2023)
Influenza represents a profoundly transmissible viral ailment primarily afflicting the respiratory system. Neuraminidase inhibitors constitute a class of antiviral therapeutics employed in the management of influenza. These inhibitors impede the libe
Externí odkaz:
https://doaj.org/article/2efc0cc5ea554b94aef5d31f9ab2711c