Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Sarka Janusova"'
Publikováno v:
PLoS ONE, Vol 18, Iss 4, p e0283431 (2023)
Linker for activation of T cells (LAT) plays a key role in T-cell antigenic signaling in mammals. Accordingly, LAT orthologues were identified in the majority of vertebrates. However, LAT orthologues were not identified in most birds. In this study,
Externí odkaz:
https://doaj.org/article/1312d26822744d3c849dd637629e3a50
Autor:
Oksana Tsyklauri, Tereza Chadimova, Veronika Niederlova, Jirina Kovarova, Juraj Michalik, Iva Malatova, Sarka Janusova, Olha Ivashchenko, Helene Rossez, Ales Drobek, Hana Vecerova, Virginie Galati, Marek Kovar, Ondrej Stepanek
Publikováno v:
eLife, Vol 12 (2023)
Regulatory T cells (Tregs) are indispensable for maintaining self-tolerance by suppressing conventional T cells. On the other hand, Tregs promote tumor growth by inhibiting anticancer immunity. In this study, we identified that Tregs increase the quo
Externí odkaz:
https://doaj.org/article/1259c927d0e9455aaea1c7377dffc5bd
Autor:
Darina Paprckova, Veronika Niederlova, Alena Moudra, Ales Drobek, Michaela Pribikova, Sarka Janusova, Kilian Schober, Ales Neuwirth, Juraj Michalik, Martina Huranova, Veronika Horkova, Michaela Cesnekova, Michaela Simova, Jan Prochazka, Jana Balounova, Dirk H. Busch, Radislav Sedlacek, Martin Schwarzer, Ondrej Stepanek
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Mature T cells are selected for recognizing self-antigens with low to intermediate affinity in the thymus. Recently, the relative differences in self-reactivity among individual T-cell clones were appreciated as important factors regulating their fat
Externí odkaz:
https://doaj.org/article/3d221b08845a4bd9b620763e054dec64
Autor:
Veronika Horkova, Ales Drobek, Darina Paprckova, Veronika Niederlova, Avishek Prasai, Valeria Uleri, Daniela Glatzova, Markus Kraller, Michaela Cesnekova, Sarka Janusova, Eva Salyova, Oksana Tsyklauri, Theresa A. Kadlecek, Katerina Krizova, René Platzer, Kilian Schober, Dirk H. Busch, Arthur Weiss, Johannes B. Huppa, Ondrej Stepanek
Publikováno v:
Nature Immunology. 24:174-185
The kinase LCK and CD4/CD8 co-receptors are crucial components of the T cell antigen receptor (TCR) signaling machinery, leading to key T cell fate decisions. Despite decades of research, the roles of CD4–LCK and CD8–LCK interactions in TCR trigg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::558e5771858f2dd70484f422099c8b4e
https://doi.org/10.1038/s41590-022-01366-0
https://doi.org/10.1038/s41590-022-01366-0
Autor:
Oksana Tsyklauri, Tereza Chadimova, Veronika Niederlova, Jirina Kovarova, Juraj Michalik, Iva Malatova, Sarka Janusova, Olha Ivashchenko, Helene Rossez, Ales Drobek, Hana Vecerova, Virginie Galati, Marek Kovar, Ondrej Stepanek
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d2857041c2c03a18ec255c7325fd3a87
https://doi.org/10.7554/elife.79342.sa2
https://doi.org/10.7554/elife.79342.sa2
Autor:
Ales Drobek, Juraj Michalik, Helene Rossez, Iva Malatova, Ondrej Stepanek, Marek Kovar, Hana Vecerova, Veronika Niederlova, Sarka Janusova, Virginie Galati, Jirina Kovarova, Oksana Tsyklauri, Tereza Chadimova
Regulatory T cells (Tregs) are indispensable for maintaining self-tolerance by suppressing conventional T cells. On the other hand, Tregs promote tumor growth by inhibiting anti-cancer immunity. In this study, we identified that Tregs increase the qu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::599aeca3e9b07d430f109c214a4a66f9
https://doi.org/10.1101/2021.11.10.467495
https://doi.org/10.1101/2021.11.10.467495