Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Sarka Holasova"'
Autor:
Filip Kunc, Radovan Haluza, Sarka Holasova, M. Šafářová, Hana Radilova, Martin Bunček, V. Bačkovská
Publikováno v:
Chromatographia. 62:263-269
The retention behavior of unmodified phosphodiester mixed-sequence oligonucleotides has been investigated under different conditions on a glycidyl methacrylate-based, DEAE-modified anion-exchange Biospher GMB 1000Q column. It was verified that separa
Autor:
Martin Bunček, Hana Radilova, Filip Kunc, Sarka Holasova, Martina Safarova, Alena Víšková, Antonin Libra
Publikováno v:
Molecular and cellular biochemistry. 330(1-2)
Cyclooxygenases are key enzymes in the arachidonic acid metabolism. Their unstable intermediate, prostaglandin H(2), is further metabolized to bioactive lipids by various downstream enzymes. In this study, utilizing short hairpin RNAs, we prepared a
Autor:
Filip Kunc, M Safárová, Sarka Holasova, Martin Bunček, Hana Radilova, V. Bačkovská, Radovan Haluza
Publikováno v:
Analytical biochemistry. 348(2)
The retention behavior of the unmodified phosphodiester oligonucleotide sequence isomers was investigated on two different anion exchange columns: Biospher GMB 1000Q (based on DEAE-modified glycidyl methacrylate) and PolyWAX LP (based on silica with
Autor:
Radovan Haluza, Hana Radilova, Miroslav Červinka, Martina Šafářová, Doris Vokurková, Martin Mojžíšek, Sarka Holasova, Martin Bunček
Publikováno v:
Molecular and cellular biochemistry. 276(1-2)
Antisense and antigene oligonucleotides (ONs) are attractive drugs for gene therapy, but major limiting factors for their routine use are inefficient cellular uptake and low accessibility to the target sites. Adding various lipophilic conjugates to t
Publikováno v:
Molecular & Cellular Biochemistry; Oct2009, Vol. 330 Issue 1/2, p131-140, 10p