Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Sarjubhai A. Patel"'
Publikováno v:
Concussion, Vol 2, Iss 4 (2017)
Aim: A small but notable number of individuals who suffer a concussion report ongoing cognitive difficulties. This preliminary study investigated the efficacy of repetitive test application to disc...
Externí odkaz:
https://doaj.org/article/b7abecce027d43e5923c9987c7e82b56
Autor:
M Campbell, J Zwicker, Charles M. Thompson, Richard J. Bridges, A Diaz-Correa, Sarjubhai A. Patel, H Little, D M Hitt, David C. Holley, J Dark, M Nehser, D Schweitzer
Publikováno v:
Neurochemical Research. 45:1375-1386
The cystine/glutamate antiporter system Xc- (SXc-) mediates the exchange of intracellular L-glutamate (L-Glu) with extracellular L-cystine (L-Cys2). Both the import of L-Cys2 and the export of L-Glu take on added significance in CNS cells, especially
Autor:
Richard J. Bridges, David M Hitt, Jeffery D Zwicker, Charles M. Thompson, Sarjubhai A. Patel, John M. Gerdes, Chih-Kai Chao
Publikováno v:
Neurochem Res
The vesicular glutamate transporter (VGLUT) facilitates the uptake of glutamate (Glu) into neuronal vesicles. VGLUT has not yet been fully characterized pharmacologically but a body of work established that certain azo-dyes bearing two Glu isosteres
Autor:
Prasanthan Thaveenthiran, James H. Brennan, Edmond Sorich, Nanda Surendran, Jeffrey V. Rosenfeld, Mark Fitzgerald, Biswadev Mitra, Thomas F. Rau, Sarjubhai A. Patel
Publikováno v:
Journal of Clinical Neuroscience. 38:37-42
Prediction of post-concussive syndrome after apparent mild traumatic brain injury (TBI) and subsequent cognitive recovery remains challenging, with substantial limitations of current methods of cognitive testing. This pilot study aimed to determine i
Publikováno v:
Concussion
Aim: A small but notable number of individuals who suffer a concussion report ongoing cognitive difficulties. This preliminary study investigated the efficacy of repetitive test application to discern cognitive impairment in those with ongoing sympto
Autor:
Diane M. Brooks, Sarjubhai A. Patel, Eric D. Wohlgehagen, Erin O. Semmens, Edmond Sorich, Thomas F. Rau, Alan J. Pearce
Publikováno v:
Experimental neurology. 297
Multiple mild traumatic brain injury (mmTBI), in certain cases, produces persistent symptoms. However, the molecular mechanisms underlying these symptoms remain unclear. Here, we demonstrate extended pathological changes in the rat brain following mm
Autor:
Jayme L. Newell, Steven W. McDaniel, Nicholas R. Natale, Richard J. Bridges, Charles M. Keyari, Sarjubhai A. Patel, Philippe Diaz
Publikováno v:
Neurochemistry International. 73:132-138
The system xc(-) antiporter is a plasma membrane transporter that mediates the exchange of extracellular l-cystine with intracellular l-glutamate. This exchange is significant within the context of the CNS because the import of l-cystine is required
Autor:
Sambit Mohapatra, Charles T. Leonard, Adriana M. Degani, Maria Santos, Thomas F. Rau, Alessander Danna-Dos-Santos, Sarjubhai A. Patel
Publikováno v:
Brain injury. 31(1)
The purpose of this study was to investigate the effects of mild traumatic brain injury (mTBI) on multiple postural indices that characterize body sway behaviour.The body's centre of pressure (COP) displacement was recorded from 11 individuals with a
Autor:
Jayme L. Newell, Sarjubhai A. Patel, Richard J. Bridges, Joseph Mirzaei, Michael Braden, Nicholas R. Natale, Stephen A. Smith, John Rudolph, Afnan A. Matti
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 23:5931-5935
Microwave accelerated reaction system (MARS) technology provided a good method to obtain selective and open isoxazole ligands that bind to and inhibit the Sx c - antiporter. The MARS provided numerous advantages, including: shorter time, better yield
Publikováno v:
British Journal of Pharmacology. 165:20-34
System xc- is an amino acid antiporter that typically mediates the exchange of extracellular l-cystine and intracellular l-glutamate across the cellular plasma membrane. Studied in a variety of cell types, the import of l-cystine through this transpo