Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Sarithaa Sellaththurai"'
Autor:
Sarithaa Sellaththurai, Sumi Jung, Myoung-Jin Kim, Kishanthini Nadarajapillai, Subothini Ganeshalingam, Joon Bum Jeong, Jehee Lee
Publikováno v:
Biomolecules, Vol 13, Iss 2, p 324 (2023)
Stimulator of interferon genes (STING) is an adapter protein that is activated when cyclic dinucleotides (CDNs) are present. CDNs originate from the cytosolic DNA of both pathogens and hosts. STING activation promotes efficient immune responses again
Externí odkaz:
https://doaj.org/article/a508d65cb3c14d04b9acb0202db2643f
Autor:
Sarithaa Sellaththurai, Subothini Ganeshalingam, Sumi Jung, Ji Yong Choi, Dae-Jung Kim, Jehee Lee
Publikováno v:
Fishshellfish immunology. 131
Peptidoglycan recognition proteins (PGRPs) belong to the pattern recognition receptor (PRR) family and are conserved from insects to mammals. PGRPs show specific binding abilities to peptidoglycans (PGNs) in various microbes. In this study, molecular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2171ac1e76ee1bcde39f11a743d98cb8
https://pubmed.ncbi.nlm.nih.gov/36241004
https://pubmed.ncbi.nlm.nih.gov/36241004
Publikováno v:
Fish & Shellfish Immunology. 111:152-159
The tetraspanin superfamily proteins are transmembrane proteins identified in a diverse range of eukaryotic organisms. Tetraspanins are involved in a variety of essential biological functions, including cell differentiation, adhesion, migration, sign
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51b2f13bcfd3d781d1cd229104ebedb7
https://doi.org/10.1016/j.fsi.2021.01.016
https://doi.org/10.1016/j.fsi.2021.01.016
Autor:
M.D. Neranjan Tharuka, K.A.S.N. Shanaka, Hyerim Yang, Jehee Lee, Thanthrige Thiunuwan Priyathilaka, Sarithaa Sellaththurai
Publikováno v:
Fish & Shellfish Immunology. 99:59-72
Innate immunity is characterized by nonspecific, prompt reactions toward armada of antigens. Animals funnel down a repertoire of immune stimulants to activate non-selective defense mechanisms rapidly. This study was conducted to characterize the rock
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f3725553787c00f9ca050e52d62242f
https://doi.org/10.1016/j.fsi.2020.01.060
https://doi.org/10.1016/j.fsi.2020.01.060
Autor:
Kishanthini Nadarajapillai, H.M.V. Udayantha, Sarithaa Sellaththurai, T.D.W. Kasthuriarachchi, Gaeun Kim, Jehee Lee
Publikováno v:
Fish & Shellfish Immunology. 132:108490
Beclin-1, the mammalian ortholog of the yeast autophagy-related gene 6 (Atg 6), is a key regulator of autophagy. A variety of health and disease conditions in mammals are intricately related to the broad spectrum of beclin-1 functions. Nevertheless,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdabac3ec189e762879270d0c5406627
https://doi.org/10.1016/j.fsi.2022.108490
https://doi.org/10.1016/j.fsi.2022.108490
Autor:
Sumi Jung, Rajamanthrilage Kasun Madusanka, K.A.S.N. Shanaka, Hyerim Yang, Jehee Lee, K.P. Madushani, Sarithaa Sellaththurai, M.D. Neranjan Tharuka
Publikováno v:
Fishshellfish immunology. 108
Animal defense system constitutes a series of distinct mechanisms that specifically defend against microbial invasion. Understanding these complex biological mechanisms is of paramount importance for implementing disease prevention strategies. In thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50f97a5038bbe52bbe7060f2ea8a0fb6
https://pubmed.ncbi.nlm.nih.gov/33259930
https://pubmed.ncbi.nlm.nih.gov/33259930
Autor:
Kishanthini Nadarajapillai, Sukkyoung Lee, Sarithaa Sellaththurai, K.A.S.N. Shanaka, Sumi Jung, W.K.M. Omeka, Jehee Lee
Publikováno v:
Fishshellfish immunology. 106
Calreticulin (CRT) is a multifunctional ubiquitous protein that is widely presented in all cells in eukaryotes except erythrocytes. CRT is well known for diverse cellular functions such as endoplasmic reticulum (ER)-specialized protein quality contro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::732ded1070123768fd037028c4c2b6fd
https://pubmed.ncbi.nlm.nih.gov/32805417
https://pubmed.ncbi.nlm.nih.gov/32805417
Autor:
Thanthrige Thiunuwan Priyathilaka, Jehee Lee, D.S. Liyanage, Sarithaa Sellaththurai, K.A.S.N. Shanaka, Hyerim Yang
Publikováno v:
Fish & Shellfish Immunology
Malectin is a carbohydrate-binding lectin protein found in the endoplasmic reticulum (ER). It selectivity binds to Glc2-N-glycan and is involved in a glycoprotein quality control mechanism. Even though malectin may play a role in immunity, its role i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5ce48b0c3307fcd229eada4b6791b26
https://pubmed.ncbi.nlm.nih.gov/32087279
https://pubmed.ncbi.nlm.nih.gov/32087279
Publikováno v:
Fishshellfish immunology. 89
Organisms possess a cellular antioxidant defense system inclusive of ROS scavengers to maintain the homeostasis of antioxidant levels. Catalase is a major ROS scavenger enzyme that plays a significant role in the antioxidant defense mechanism of orga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c5805a011e10d9232ac2f25c32a728c
https://pubmed.ncbi.nlm.nih.gov/30936047
https://pubmed.ncbi.nlm.nih.gov/30936047
Autor:
D.S. Liyanage, Sukkyoung Lee, Taehyug Jeong, Jehee Lee, Kishanthini Nadarajapillai, Sarithaa Sellaththurai
Publikováno v:
Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology. 240:108917
Glutathione-S-transferase (GST) is a key enzyme in the phase-II detoxification process and is a biomarker of oxidative stress. In this study, we analyzed the molecular, biochemical, and antioxidant properties of GST alpha-4 from Hippocampus abdominal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e38a4fd3539d7e24117e3212c8619f2a
https://doi.org/10.1016/j.cbpc.2020.108917
https://doi.org/10.1016/j.cbpc.2020.108917