Zobrazeno 1 - 10 of 20 pro vyhledávání: '"Sarita Rajender Potlapally"'
1
Akademický článek
Identification of potential antiviral lead inhibitors against SARS-CoV-2 main protease: Structure-guided virtual screening, docking, ADME, and MD Simulation based approach
Autor: Goverdhan Lanka, Revanth Bathula, Balaram Ghosh, Sarita Rajender Potlapally
Publikováno v: Artificial Intelligence Chemistry, Vol 1, Iss 2, Pp 100015- (2023)
The novel coronavirus disease (COVID-19) was caused by a new strain of the virus SARS-CoV-2 in December 2019 emerged as deadly pandemic that affected millions of people worldwide. Factors such as lack of effective drugs, vaccine resistance, gene muta
Externí odkaz: https://doaj.org/article/8b47f4671a7b4438bc45a506e6809525
Zobrazit plný text záznamu
5
Homology modelling and virtual screening to explore potent inhibitors for MAP2K3 protein
Autor: Goverdhan Lanka, Alok Jain, Sarita Rajender Potlapally, Gururaj Somadi, Nazmina Vhora, Sivan Sree Kanth, Manan Bhargavi
Publikováno v: Structural Chemistry. 32:1039-1051
MAP2K3 protein is mitogen-activated protein kinase belonging to the family of kinases involved in intracellular cell proliferation. The mammalian MAPK family that consists of ERK, p38 and JNK signalling pathway is showing a critical role in the regul
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::425f0c39e998c4af1488536bd3189ce2
https://doi.org/10.1007/s11224-020-01667-w
Zobrazit plný text záznamu
7
Structural Insight into PRMT5 Inhibitors through Amalgamating Pharmacophore-Based Virtual Screening, ADME-Toxicity and Binding Energy Studies and Identify New Inhibitors by Molecular Docking
Autor: Goverdhan Lanka, Revanth Bathula, Narasimha Muddagoni, Sarita Rajender Potlapally, Gururaj Somadi, Sree Kanth Sivan
Protein arginine methyltransferase 5 (PRMT5) is a member of the methyltransferases family, a type II arginine enzyme that is crucial for many cellular processes and is associated with many cancer diseases. In this study, pharmacophore-based 3D QSAR m
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::052eb221e02edeeaf53e3beee858c79e
https://doi.org/10.21203/rs.3.rs-819089/v1
Zobrazit plný text záznamu
8
Structure-based identification of potential novel inhibitors targeting FAM3B (PANDER) causing type 2 diabetes mellitus through virtual screening
Autor: Sravanthi Nakkala, Goverdhan Lanka, Manan Bhargavi, Mahendar Dasari, Revanth Bathula, Gururaj Somadi, Sarita Rajender Potlapally
Publikováno v: Journal of Receptors and Signal Transduction. 39:253-263
Type 2 diabetes mellitus is a metabolic disorder that requires potent therapeutic approaches. The FAM3B is a cytokine-like protein also referred to as PANcreatic-DERrived factor (PANDER) which mainly exists in pancreatic islets. In the process of ide
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42615c760c73799ea71afbebb8f60f9c
https://doi.org/10.1080/10799893.2019.1660897
Zobrazit plný text záznamu
10
Azolium analogues as CDK4 inhibitors: Pharmacophore modeling, 3D QSAR study and new lead drug discovery
Autor: Rajender Vadija, Vishwanath Ramatenki, Sarita Rajender Potlapally, Rohini Rondla, Uma Vuruputuri, Thirupathi Mukkera, Lavanya Souda Padma Rao
Publikováno v: Journal of Molecular Structure. 1134:482-491
The cyclin-dependent kinase 4 (CDK4) enzyme is a key regulator in cell cycle G1 phase progression. It is often overexpressed in variety of cancer cells, which makes it an attractive therapeutic target for cancer treatment. A number of chemical scaffo
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c60d0616f29e4b791196be423133586a
https://doi.org/10.1016/j.molstruc.2016.12.106
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje