Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Sarit Smolikov"'
Publikováno v:
Bio-Protocol, Vol 8, Iss 24 (2018)
DNA double-strand breaks (DSBs) are toxic lesions that every cell must accurately repair in order to survive. The repair of DSBs is an integral part of a cell life cycle and can lead to lethality if repaired incorrectly. Laser microirradiation is an
Externí odkaz:
https://doaj.org/article/df95f82198e544bab0dbd96e7d37c9ee
Publikováno v:
PLoS Genetics, Vol 5, Iss 10, p e1000669 (2009)
The proper assembly of the synaptonemal complex (SC) between homologs is critical to ensure accurate meiotic chromosome segregation. The SC is a meiotic tripartite structure present from yeast to humans, comprised of proteins assembled along the axes
Externí odkaz:
https://doaj.org/article/2792af8aaa134beeaba9439f278ce79a
Publikováno v:
PLoS Genetics, Vol 4, Iss 6, p e1000088 (2008)
The synaptonemal complex (SC), a tripartite proteinaceous structure that forms between homologous chromosomes during meiosis, is crucial for faithful chromosome segregation. Here we identify CRA-1, a novel and conserved protein that is required for t
Externí odkaz:
https://doaj.org/article/a3dd82d270754052abd0b2783f7a2b9b
Autor:
Jill M. Schumacher, Sophie Zaaijer, Sarit Smolikov, Monica P. Colaiácovo, Yanjie Gu, Carlos Egydio de Carvalho
Publikováno v:
Genes & Development. 22:2869-2885
The Shugoshin/Aurora circuitry that controls the timely release of cohesins from sister chromatids in meiosis and mitosis is widely conserved among eukaryotes, although little is known about its function in organisms whose chromosomes lack a localize
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11a16b70b8052879dffda35e617b6ad7
https://doi.org/10.1101/gad.1691208
https://doi.org/10.1101/gad.1691208
Autor:
Andreas Eizinger, Allison Hurlburt, Sarit Smolikov, Eric J Rogers, Anne M. Villeneuve, Monica P. Colaiácovo
Publikováno v:
Genetics. 176:2027-2033
SYP-3 is a new structural component of the synaptonemal complex (SC) required for the regulation of chromosome synapsis. Both chromosome morphogenesis and nuclear organization are altered throughout the germlines of syp-3 mutants. Here, our analysis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::834b5f7a6af948118c0b4ee8361fbf93
https://doi.org/10.1534/genetics.107.076968
https://doi.org/10.1534/genetics.107.076968
Autor:
Yang Shi, Sarit Smolikov, Johnathan R. Whetstine, En Li, Maite Huarte, Eric Spooner, Gongyi Zhang, Amanda C. Nottke, Zhongzhou Chen, Fei Lan, Monica P. Colaiácovo
Publikováno v:
Cell. 125:467-481
SummaryHistone methylation regulates chromatin structure, transcription, and epigenetic state of the cell. Histone methylation is dynamically regulated by histone methylases and demethylases such as LSD1 and JHDM1, which mediate demethylation of di-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dea9f12da945bcc37ec5bf1661080851
https://doi.org/10.1016/j.cell.2006.03.028
https://doi.org/10.1016/j.cell.2006.03.028
Publikováno v:
Current Genetics. 47:18-28
Eukaryotic cells invest a large proportion of their genome in maintaining telomere length homeostasis. Among the 173 non-essential yeast genes found to affect telomere length, a large proportion is involved in vacuolar traffic. When mutated, these va
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b310083320568865e146cee40fa48f3d
https://doi.org/10.1007/s00294-004-0548-y
https://doi.org/10.1007/s00294-004-0548-y
Publikováno v:
Molecular Genetics and Genomics. 268:729-738
We report the identification and characterization of transcriptional silencing at native telomeres in the budding yeast Kluyveromyces lactis. We show that K. lactis telomeres are able to repress the transcription of a gene located at the junction bet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57edd274b9819089a17ef38be3048df0
https://doi.org/10.1007/s00438-002-0788-9
https://doi.org/10.1007/s00438-002-0788-9
Autor:
Yanjie Gu, Takamune T. Saito, Sarit Smolikov, Marc Vidal, Kent L. McDonald, David E. Hill, Kristina Schild-Prüfert, Marina Hincapie, Monica P. Colaiácovo
Publikováno v:
Genetics. 189(2)
Four different SYP proteins (SYP-1, SYP-2, SYP-3, and SYP-4) have been proposed to form the central region of the synaptonemal complex (SC) thereby bridging the axes of paired meiotic chromosomes in Caenorhabditis elegans. Their interdependent locali
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5dd9102dd58d29faedf83511fb6298c7
https://pubmed.ncbi.nlm.nih.gov/21994217
https://pubmed.ncbi.nlm.nih.gov/21994217
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 5, Iss 10, p e1000669 (2009)
PLoS Genetics, Vol 5, Iss 10, p e1000669 (2009)
The proper assembly of the synaptonemal complex (SC) between homologs is critical to ensure accurate meiotic chromosome segregation. The SC is a meiotic tripartite structure present from yeast to humans, comprised of proteins assembled along the axes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b6116f41fcbdc0e93e087fa4ef40b0d
http://europepmc.org/articles/PMC2742731
http://europepmc.org/articles/PMC2742731