Galleria mellonella as an infection model to investigate virulence of Vibrio parahaemolyticus

Autor: Sariqa Wagley, Richard Borne, Jamie Harrison, Craig Baker-Austin, Donatella Ottaviani, Francesca Leoni, Varaporn Vuddhakul, Richard W. Titball

Publikováno v: Virulence, Vol 9, Iss 1, Pp 197-207 (2018)

Non-toxigenic V. parahaemolyticus isolates (tdh−/trh−/T3SS2−) have recently been isolated from patients with gastroenteritis. In this study we report that the larvae of the wax moth (Galleria mellonella) are susceptible to infection by toxigeni

Externí odkaz: https://doaj.org/article/67b2fd631683474c8982bc7ce5e30c3c

Campylobacter jejuni 11168H Exposed to Penicillin Forms Persister Cells and Cells With Altered Redox Protein Activity

Autor: Helen Morcrette, Andrea Kovacs-Simon, Richard K. Tennant, John Love, Sariqa Wagley, Zheng R. Yang, David J. Studholme, Orkun S. Soyer, Olivia L. Champion, Clive S. Butler, Richard W. Titball

Publikováno v: Frontiers in Cellular and Infection Microbiology, Vol 10 (2020)

The formation of persister cells is one mechanism by which bacteria can survive exposure to environmental stresses. We show that Campylobacter jejuni 11168H forms persister cells at a frequency of 10−3 after exposure to 100 × MIC of penicillin G f

Externí odkaz: https://doaj.org/article/fda703e1d82e4689bc308fa5cc68c432

The Application of Imaging Flow Cytometry for Characterisation and Quantification of Bacterial Phenotypes

Autor: Daniel G Barber, Ping Liu, Ann Power, Sophie R M Groenhof, David A. Parker, Sariqa Wagley, John Love

Publikováno v: Frontiers in Cellular and Infection Microbiology
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)

Bacteria modify their morphology in response to various factors including growth stage, nutrient availability, predation, motility and long-term survival strategies. Morphological changes may also be associated with specific physiological phenotypes

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33eb95a5308f3e9ffc3a163f6f7f8440

Evidence of Clostridium perfringens epsilon toxin associated with multiple sclerosis

Autor: Andrea Malaspina, Dominika Raciborska, Ben Turner, Richard W. Titball, Helen Morcrette, Sharmilee Gnanapavan, Michel R. Popoff, Richard Nicholas, N. Lewis, Sariqa Wagley, Monika Bokori-Brown, Caroline D’Arcy

Publikováno v: Multiple Sclerosis (Houndmills, Basingstoke, England)
Multiple Sclerosis Journal
Multiple Sclerosis Journal, SAGE Publications, 2018, 25 (5), pp.653-660. ⟨10.1177/1352458518767327⟩
Multiple Sclerosis Journal, 2018, 25 (5), pp.653-660. ⟨10.1177/1352458518767327⟩

Background: It was recently reported that, using Western blotting, some multiple sclerosis (MS) patients in the United States had antibodies against epsilon toxin (Etx) from Clostridium perfringens, suggesting that the toxin may play a role in the di

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::049ebf85e0d8199f06863c451b576539
https://doi.org/10.1177/1352458518767327

Genome Sequences of Four Vibrio parahaemolyticus Strains Isolated from the English Channel and the River Thames

Autor: Lucy Witherall, Clive S. Butler, Sariqa Wagley, Charles R. Tyler, Ben Temperton

Publikováno v: Microbiology Resource Announcements

Vibrio parahaemolyticus is the lead causative agent for seafood-borne human gastroenteritis. While its occurrence has traditionally been uncommon in Europe and the United Kingdom, rising sea surface temperatures have resulted in an increased prevalen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::127e43c343ebc893501305e65c3a6c4a
https://doi.org/10.1128/mra.00392-19