Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Sarina Levy-Mendelovich"'
Autor:
Eyal Elron, Joanne Yacobovich, Orly Efros, Osama Tanous, Sarina Levy-Mendelovich, Esti Shamba, Orna Steinberg-Shemer, Tracie Goldberg, Shai Izraeli, Oded Gilad
Publikováno v:
Therapeutic Advances in Hematology, Vol 15 (2024)
Objectives: Treatment of pediatric immune thrombocytopenia (ITP) is guided by the risk of bleeding. Intravenous immunoglobulin (IVIg) is one of the first-line therapy options for new-onset pediatric ITP. However, the exact optimal dose of IVIg has no
Externí odkaz:
https://doaj.org/article/c8d5ccd1d76b4ba8a69aef582f31b906
Autor:
Sarina Levy-Mendelovich, Einat Avishai, Benjamin J. Samelson-Jones, Rima Dardik, Tami Brutman-Barazani, Yael Nisgav, Tami Livnat, Gili Kenet
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 19, p 10336 (2024)
Severe protein C deficiency (SPCD) is a rare inherited thrombotic disease associated with high morbidity and mortality. In the current study, we established a viable murine model of SPCD, enabling preclinical gene therapy studies. By creating SPCD mi
Externí odkaz:
https://doaj.org/article/afc8c0dcde9742f888e5cb42d1f4a409
Autor:
Rima Dardik, Szymon Janczar, Shadan Lalezari, Einat Avishai, Sarina Levy-Mendelovich, Assaf Arie Barg, Uri Martinowitz, Katarzyna Babol-Pokora, Wojciech Mlynarski, Gili Kenet
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 14, p 11846 (2023)
Hemophilia A (HA), a rare recessive X-linked bleeding disorder, is caused by either deficiency or dysfunction of coagulation factor VIII (FVIII) resulting from deleterious mutations in the F8 gene encoding FVIII. Over the last 4 decades, the methods
Externí odkaz:
https://doaj.org/article/0848537bbfef41d384882d752fe52cbf
Autor:
Yehonatan Weinberger, Ivan Budnik, Yael Nisgav, Dahlia Palevski, Gil Ben-David, José A. Fernández, Shany Nivinsky Margalit, Sarina Levy-Mendelovich, Gili Kenet, Dov Weinberger, John H. Griffin, Tami Livnat
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 13, p 10642 (2023)
3K3A-Activated Protein C (APC) is a recombinant variant of the physiological anticoagulant APC with cytoprotective properties and reduced bleeding risks. We studied the potential use of 3K3A-APC as a multi-target therapeutic option for choroidal neov
Externí odkaz:
https://doaj.org/article/b3454c17de6e43fd9276416c1ee5569d
Autor:
Dahlia Palevski, Gil Ben-David, Yehonatan Weinberger, Rabeei Haj Daood, José A. Fernández, Ivan Budnik, Sarina Levy-Mendelovich, Gili Kenet, Yael Nisgav, Dov Weinberger, John H. Griffin, Tami Livnat
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 22, p 14196 (2022)
3K3A-Activated Protein C (APC) is a recombinant variant of the physiological anticoagulant APC with pleiotropic cytoprotective properties albeit without the bleeding risks. The anti-inflammatory activities of 3K3A-APC were demonstrated in multiple pr
Externí odkaz:
https://doaj.org/article/fadb6be406814f558453008fe350d342
Autor:
Rima Dardik, Einat Avishai, Shadan Lalezari, Assaf A. Barg, Sarina Levy-Mendelovich, Ivan Budnik, Ortal Barel, Yulia Khavkin, Gili Kenet, Tami Livnat
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 16, p 9074 (2021)
Introduction: Hemophilia A (HA) is an X-linked bleeding disorder caused by factor VIII (FVIII) deficiency or dysfunction due to F8 gene mutations. HA carriers are usually asymptomatic because their FVIII levels correspond to approximately half of the
Externí odkaz:
https://doaj.org/article/178ae0304d984c758781f63a64fb6bad
Autor:
Tami Livnat, Yehonatan Weinberger, José A. Fernández, Alaa Bashir, Gil Ben-David, Dahlia Palevski, Sarina Levy-Mendelovich, Gili Kenet, Ivan Budnik, Yael Nisgav, John H. Griffin, Dov Weinberger
Publikováno v:
Biomolecules, Vol 11, Iss 3, p 358 (2021)
The activated protein C (APC) ability to inhibit choroidal neovascularization (CNV) growth and leakage was recently shown in a murine model. A modified APC, 3K3A-APC, was designed to reduce anticoagulant activity while maintaining full cytoprotective
Externí odkaz:
https://doaj.org/article/257408fbd8ea498eaece922f8cc88963
Autor:
Eyal Klang, Sarina Levy-Mendelovich
Publikováno v:
Journal of Thrombosis and Haemostasis. 21:1055-1058
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::358300331cb99261c0fd7330567c33d6
https://doi.org/10.1016/j.jtha.2023.01.011
https://doi.org/10.1016/j.jtha.2023.01.011
Autor:
Sarina Levy‐Mendelovich, Christopher E. Walsh, Jonathan M. Schapiro, Shelly Soffer, Eyal Klang, Gili Kenet
Publikováno v:
Haemophilia. 29:784-789
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f06eb151d37ffd990272830a82758982
https://doi.org/10.1111/hae.14780
https://doi.org/10.1111/hae.14780
Autor:
Omri Cohen, Nitsan Landau, Einat Avisahai, Tami Brutman-Barazani, Ivan Budnik, Tami Livnat, Keren Asraf, Ram Doolman, Sarina Levy-Mendelovich, Orly Efros, Uri Manor, Eyal Meltzer, Gad Segal, Galia Rahav, Gili Kenet
Publikováno v:
Acta Haematologica. 146:151-160
Introduction: Coronavirus disease 2019 (COVID-19) disease is associated with coagulopathy and an increased risk of thrombosis. An association between thrombin generation (TG) capacity, disease severity, and outcomes has not been well described. Metho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91982eee904643b5333faab16f8f32c3
https://doi.org/10.1159/000527581
https://doi.org/10.1159/000527581