Zobrazeno 1 - 10 of 27 pro vyhledávání: '"Sarina Bains"'
1
Akademický článek
Mouse DCUN1D1 (SCCRO) is required for spermatogenetic individualization.
Autor: Guochang Huang, Andrew J Kaufman, Russell J H Ryan, Yevgeniy Romin, Laryssa Huryn, Sarina Bains, Katia Manova-Todorova, Patricia L Morris, Gary R Hunnicutt, Carrie A Adelman, John H J Petrini, Y Ramanathan, Bhuvanesh Singh
Publikováno v: PLoS ONE, Vol 14, Iss 1, p e0209995 (2019)
Squamous cell carcinoma-related oncogene (SCCRO, also known as DCUN1D1) is a component of the E3 for neddylation. As such, DCUN1D1 regulates the neddylation of cullin family members. Targeted inactivation of DCUN1D1 in mice results in male-specific i
Externí odkaz: https://doaj.org/article/b2c5cb5ef6f94ce8bb3cf00f8422e4c2
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2
Supplementary Tables 1 - 7 from Oncogenic Function of SCCRO5/DCUN1D5 Requires Its Neddylation E3 Activity and Nuclear Localization
Autor: Bhuvanesh Singh, Suresh Y. Ramanathan, Ronald Ghossein, Mithat Gönen, Manish Shaha, Elizabeth Buss, Sarina Bains, Kushyup Shah, Guochang Huang, Víola B. Weeda, Claire C. Bommeljé
PDF file - 113K, Supplementary Table S1. Oral squamous cell carcinoma- patient and tumor characteristics. Supplementary Table S2. Lung squamous cell carcinoma -patient and tumor characteristics. Supplementary Table S3. Thyroid Carcinoma -patient and
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::156b6f220c108ea13157d0d6a6c0a1c7
https://doi.org/10.1158/1078-0432.22450373
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4
Data from Oncogenic Function of SCCRO5/DCUN1D5 Requires Its Neddylation E3 Activity and Nuclear Localization
Autor: Bhuvanesh Singh, Suresh Y. Ramanathan, Ronald Ghossein, Mithat Gönen, Manish Shaha, Elizabeth Buss, Sarina Bains, Kushyup Shah, Guochang Huang, Víola B. Weeda, Claire C. Bommeljé
Purpose: To determine mechanisms by which SCCRO5 (aka DCUN1D5) promotes oncogenesis.Experimental Design:SCCRO5 mRNA and protein expression were assessed in 203 randomly selected primary cancer tissue samples, matched histologically normal tissues, an
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3ddc22c008dea913a9ccf460f758aa2
https://doi.org/10.1158/1078-0432.c.6521921.v1
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5
Supplementary Figure 3 from Oncogenic Function of SCCRO5/DCUN1D5 Requires Its Neddylation E3 Activity and Nuclear Localization
Autor: Bhuvanesh Singh, Suresh Y. Ramanathan, Ronald Ghossein, Mithat Gönen, Manish Shaha, Elizabeth Buss, Sarina Bains, Kushyup Shah, Guochang Huang, Víola B. Weeda, Claire C. Bommeljé
PDF file - 56K, Correlation between SCCRO5 copy number alterations and mRNA expression measured by RNA seq (deep sequencing for RNA), in head and neck squamous cell carcinomas from The Cancer Genome Atlas, normalized by z-score transformation. Het, h
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c812ffa56055e44b6dca107f8cdf1c20
https://doi.org/10.1158/1078-0432.22450382.v1
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6
Supplementary Figure 2 from Oncogenic Function of SCCRO5/DCUN1D5 Requires Its Neddylation E3 Activity and Nuclear Localization
Autor: Bhuvanesh Singh, Suresh Y. Ramanathan, Ronald Ghossein, Mithat Gönen, Manish Shaha, Elizabeth Buss, Sarina Bains, Kushyup Shah, Guochang Huang, Víola B. Weeda, Claire C. Bommeljé
PDF file - 840K, A, Western blot analysis of lysates of NIH-3T3 cells stably transfected with vector alone, SCCRO5, SCCRO5_∆1-10 or SCCRO5_D195N/A219R/D225N and probed with antibody against SCCRO5 or tubulin as a loading control. SCCRO5_∆1-10 is
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35cac495e1bfc6f5f0f8ed3b93af0a61
https://doi.org/10.1158/1078-0432.22450385.v1
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Impact of multikinase inhibitor approval on survival and physician practice patterns in advanced or metastatic medullary thyroid carcinoma
Autor: Jessica W. Thiesmeyer, Dessislava Stefanova, Rasa Zarnegar, Toni Beninato, Thomas J. Fahey, Brendan M. Finnerty, Timothy M. Ullmann, Sarina Bains, Jessica Limberg
Publikováno v: Surgery. 169:50-57
This study aimed to identify whether multikinase inhibitor approval for medullary thyroid carcinoma was associated with changes in systemic therapy administration or overall survival.The National Cancer Database was queried for advanced medullary thy
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3630db7315f2b5b2bd833f7b0bdf9097
https://doi.org/10.1016/j.surg.2020.03.021
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10
Akademický článek
SCCRO Promotes Glioma Formation and Malignant Progression in Mice
Autor: Stephen R. Broderick, Benjamin J. Golas, Duykhanh Pham, Christopher W. Towe, Simon G. Talbot, Andrew Kaufman, Sarina. Bains, Laryssa A. Huryn, Yoshihiro Yonekawa, Diane Carlson, Dolores Hambardzumyan, Yegnanarayana Ramanathan, Bhuvanesh Singh
Publikováno v: Neoplasia: An International Journal for Oncology Research, Vol 12, Iss 6, Pp 476-484 (2010)
Originally identified as an oncogene activated by amplification in squamous cell carcinomas, several lines of evidence now suggest that squamous cell carcinoma-related oncogene (SCCRO; aka DCUN1D1) may play a role in the pathogenesis of a wide range
Externí odkaz: https://doaj.org/article/176a8216b533461d8da1bd493df5dcb2
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