Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Sarika Saraswati"'
Publikováno v:
Frontiers in Molecular Biosciences, Vol 11 (2024)
Externí odkaz:
https://doaj.org/article/9c535efc690a4560a96605e578d79cbc
Autor:
Trayambak Basak, Sarika Saraswati
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
Externí odkaz:
https://doaj.org/article/8a4a090e73f644ec9c4ad9e5482e3b66
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
Activated fibroblasts are key contributors to tissue repair after cardiac injury. Here, Saraswati et al. identify and characterize a subpopulation of FSP1-positive cardiac fibroblasts with proangiogenic properties in infarcted hearts.
Externí odkaz:
https://doaj.org/article/14eb6c67dc5b41878fa0cc1a0e96eba2
Publikováno v:
PLoS ONE, Vol 5, Iss 11, p e15521 (2010)
Wnt signaling plays an important role in developmental and stem cell biology. To test the hypothesis that temporary inhibition of Wnt signaling will enhance granulation tissue and promote angiogenesis in tissue repair, we employed a recently characte
Externí odkaz:
https://doaj.org/article/76af860fea1b45389cf0ae94aabae754
Publikováno v:
The FASEB Journal
Nearly 6 million Americans suffer from heart failure. Increased fibrosis contributes to functional decline of the heart that leads to heart failure. Previously, we identified a mechanosensitive protein, small proline‐rich repeat 3 (SPRR3), in vascu
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
Nature Communications
Nature Communications
Fibrosis accompanying wound healing can drive the failure of many different organs. Activated fibroblasts are the principal determinants of post-injury pathological fibrosis along with physiological repair, making them a difficult therapeutic target.
Publikováno v:
Circulation Research. 127
Almost 6.5 million people in United States suffer from heart failure (HF). Diastolic HF following non-ischemic cardiac insult is a progressive condition with limited effective therapies underscoring the urgency to invest in identifying novel therapeu
Publikováno v:
J Vis Exp
Cardiac fibrosis in response to injury is a physiological response to wound healing. Efforts have been made to study and target fibroblast subtypes that mitigate fibrosis. However, fibroblast research has been hindered due to the lack of universally
Autor:
Ethan Lee, Pampee P. Young, Dikshya Bastakoty, Justin M M Cates, Sarika Saraswati, Lillian B. Nanney
Publikováno v:
The FASEB Journal. 29:4881-4892
Wound healing in mammals is a fibrotic process. The mechanisms driving fibrotic (as opposed to regenerative) repair are poorly understood. Herein we report that therapeutic Wnt inhibition with topical application of small-molecule Wnt inhibitors can
Publikováno v:
Stem Cells. 33:1333-1344
MSCs encounter extended hypoxia in the wound microenvironment yet little is known about their adaptability to this prolonged hypoxic milieu. In this study, we evaluated the cellular and molecular response of MSCs in extended hypoxia (1% O2) versus no