Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Sarika Chaudhari"'
Autor:
Sarika Chaudhari, Grace S. Pham, Calvin D. Brooks, Viet Q. Dinh, Cassandra M. Young-Stubbs, Caroline G. Shimoura, Keisa W. Mathis
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Despite extensive research and a plethora of therapeutic options, hypertension continues to be a global burden. Understanding of the pathological roles of known and underexplored cellular and molecular pathways in the development and maintenance of h
Externí odkaz:
https://doaj.org/article/f2cbc185afbf42faa3ae4c0d0c552e1e
Autor:
Weizu Li, Yanfeng Ding, Crystal Smedley, Yanxia Wang, Sarika Chaudhari, Lutz Birnbaumer, Rong Ma
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract The present study was conducted to determine if TRPC6 regulates glomerular filtration rate (GFR) and the contractile function of glomerular mesangial cells (MCs). GFR was assessed in conscious TRPC6 wild type and knockout mice, and in anesth
Externí odkaz:
https://doaj.org/article/3e7482ebd6724f61a2a0139a35c905f1
Autor:
Sarika Chaudhari, Bradley M. D’Souza, Jessica Y. Morales, Cassandra M. Young-Stubbs, Caroline G. Shimoura, Rong Ma, Keisa W. Mathis
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 323:H1331-H1342
There is a high prevalence of hypertension in male and female SLE; however, male SLE mice are hypertensive without renal involvement. The development of hypertension in female SLE mice is renocentric and strongly associated with injurious renal mecha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3eba8a1a14f016c3801f1e858040fb75
https://doi.org/10.1152/ajpheart.00286.2022
https://doi.org/10.1152/ajpheart.00286.2022
Autor:
Viet Dinh, Sarika Chaudhari, Caroline Gusson Shimoura Almeida Lima, Cassandra Young-Stubbs, Keisa Mathis
Publikováno v:
Physiology. 38
Hypertension is the leading risk factor for cardiovascular morbidity and mortality, and growing evidence implicates chronic renal inflammation as a culprit in the development of hypertension, such as in the case of the autoimmune disease systemic lup
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4b832b184bebf718c388fe25ea6ef108
https://doi.org/10.1152/physiol.2023.38.s1.5734907
https://doi.org/10.1152/physiol.2023.38.s1.5734907
Autor:
Sarika Chaudhari, Cassandra Young-stubbs, Caroline Shimoura, Viet Dinh, Robert Luedtke, Keisa Mathis
Publikováno v:
Physiology. 38
Systemic lupus erythematosus (SLE) is a female dominant autoimmune disease that presents with prominent renal injury and hypertension contributing to the morbidity and mortality. While the causality and association of the renal injury and hypertensio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d2d007164fb7085465cc9a39fee5b10
https://doi.org/10.1152/physiol.2023.38.s1.5734411
https://doi.org/10.1152/physiol.2023.38.s1.5734411
Autor:
Veena R. Agarwal, Somesh Sharma, Avinash More, Anagha Damre, Rajiv Sharma, Sanjay Kumar, Nilambari Yewalkar, Vijaykumar Deore, Lakshmi S. Kolla, Julie Bose, Sarika Chaudhari, Nikesh Desai, Magesh Venkatraman, Asavari Joshi, Srinivas Boreddy, Dimple R. Bhatia, Archana Jalota-Badhwar
Supplementary Table S1; Supplementary Figures S1-S2. Supplementary Table 1. A) IC50 value of P7170 in pan-PI3K. B) Kinase inhibition data (ProQinase) of P7170 at 250 nM and 1. 5 μM.C) Kinase inhibition profile (KINOMEscan; 320 kinases) of P717
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d25173fc0ee98eb8b60c1909b4e3f991
https://doi.org/10.1158/1535-7163.22502247.v1
https://doi.org/10.1158/1535-7163.22502247.v1
Publikováno v:
Hypertension. 79
Systemic lupus erythematosus (SLE) is an autoimmune disorder linked to chronic renal inflammation and prevalent hypertension. We use an established murine model of SLE (NZBWF1) to mechanistically link renal inflammation to the development of hyperten
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e7449a99b972ac4142a0a0a0b8060784
https://doi.org/10.1161/hyp.79.suppl_1.097
https://doi.org/10.1161/hyp.79.suppl_1.097
Autor:
Caroline Gusson Shimoura, Cassandra M Young-Stubbs, Sarika Chaudhari, Viet Q Dinh, Keisa W Mathis
Publikováno v:
Hypertension. 79
Renal inflammation promotes hypertension in systemic lupus erythematosus (SLE). Our recent studies suggest that renal inflammation is regulated by the vagally-mediated cholinergic anti-inflammatory pathway, and that vagal tone is reduced in SLE mice.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f2511ddf5536eed32210fbec53d23261
https://doi.org/10.1161/hyp.79.suppl_1.p073
https://doi.org/10.1161/hyp.79.suppl_1.p073
Autor:
Sarika Chaudhari, Bradley M. D'Souza, Jessica Y. Morales, Caroline Lima, Cassandra M. Young‐Stubbs, Rong Ma, Keisa W. Mathis
Publikováno v:
The FASEB Journal. 36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::69dfb7045cb7bdaeae0f07622a34d9e3
https://doi.org/10.1096/fasebj.2022.36.s1.r2320
https://doi.org/10.1096/fasebj.2022.36.s1.r2320
Publikováno v:
Am J Physiol Renal Physiol
Systemic lupus erythematosus (SLE) is characterized by hypertension that results from chronic renal inflammation and dysautonomia in the form of dampened vagal tone. In health, the vagus nerve regulates inflammatory processes through mechanisms like
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18c8ed7eb907c24c2ba1df124b489b8f
https://doi.org/10.1152/ajprenal.00201.2020
https://doi.org/10.1152/ajprenal.00201.2020