X-Chromosome Association Study in Latin American Cohorts Identifies New Loci in Parkinson's Disease.

Autor: Leal TP; Lerner Research Institute, Genomic Medicine, Cleveland Clinic, Cleveland, Ohio, USA., Rao SC; The Parkinson's Foundation, Miami, Florida, USA., French-Kwawu JN; Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, Maryland, USA., Gouveia MH; Center for Research on Genomics and Global Health, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, USA., Borda V; Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, Maryland, USA., Bandres-Ciga S; Center for Alzheimer's and Related Dementias, National Institutes of Health, Bethesda, Maryland, USA., Inca-Martinez M; Lerner Research Institute, Genomic Medicine, Cleveland Clinic, Cleveland, Ohio, USA., Mason EA; University of South Carolina School of Medicine, Columbia, South Carolina, USA., Horimoto ARVR; Division of Aging, Brigham and Women's Hospital, Boston, Massachusetts, USA., Loesch DP; Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, Maryland, USA., Sarihan EI; Lerner Research Institute, Genomic Medicine, Cleveland Clinic, Cleveland, Ohio, USA., Cornejo-Olivas MR; Neurogenetics Working Group, Universidad Científica del Sur, Lima, Peru.; Neurogenetics Research Center, Instituto Nacional de Ciencias Neurologicas, Lima, Peru., Torres LE; Movement Disorders Unit, Instituto Nacional de Ciencias Neurologicas, Lima, Peru., Mazzetti-Soler PE; Neurogenetics Research Center, Instituto Nacional de Ciencias Neurologicas, Lima, Peru.; Departamento de Medicina Humana, Universidad Nacional Mayor de San Marcos, Lima, Peru., Cosentino C; Movement Disorders Unit, Instituto Nacional de Ciencias Neurologicas, Lima, Peru., Sarapura-Castro EH; Neurogenetics Research Center, Instituto Nacional de Ciencias Neurologicas, Lima, Peru., Rivera-Valdivia A; Neurogenetics Research Center, Instituto Nacional de Ciencias Neurologicas, Lima, Peru., Medina AC; Universidad Nacional del Altiplano, Puno, Peru., Dieguez EM; Neurology Institute, Universidad de la República, Montevideo, Uruguay., Raggio VE; Department of Genetics, Facultad de Medicina, Universidad de la República, Montevideo, Uruguay., Lescano A; Neurology Institute, Universidad de la República, Montevideo, Uruguay., Tumas V; Ribeirão Preto Medical School, Universidade de São Paulo, Ribeirão Preto, Brazil., Borges V; Movement Disorders Unit, Department of Neurology and Neurosurgery, Universidade Federal de São Paulo, São Paulo, Brazil., Ferraz HB; Movement Disorders Unit, Department of Neurology and Neurosurgery, Universidade Federal de São Paulo, São Paulo, Brazil., Rieder CR; Departamento de Neurologia, Universidade Federal de Ciências da Saúde de Porto Alegre, Porto Alegre, Brazil., Schumacher Schuh A; Serviço de Neurologia, Hospital de Clínicas de Porto Alegre, Porto Alegre, Brazil.; Departamento de Farmacologia, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil., Santos-Lobato BL; Instituto de Ciências da Saúde, Universidade Federal do Pará, Belém, Brazil., Velez-Pardo C; Neuroscience Research Group, Medical Research Institute, Faculty of Medicine, Universidad de Antioquia, Medellín, Colombia., Jimenez-Del-Rio M; Neuroscience Research Group, Medical Research Institute, Faculty of Medicine, Universidad de Antioquia, Medellín, Colombia., Lopera F; Neuroscience Research Group, Medical Research Institute, Faculty of Medicine, Universidad de Antioquia, Medellín, Colombia., Moreno S; Neuroscience Research Group, Medical Research Institute, Faculty of Medicine, Universidad de Antioquia, Medellín, Colombia., Chana-Cuevas P; CETRAM, Facultad de Ciencias Médicas, Universidad de Santiago de Chile, Santiago, Chile., Fernandez W; Neuroscience and Cell Death Research Groups, Medical School and Genetic Institute, Universidad Nacional de Colombia, Bogotá, Colombia., Arboleda G; Neuroscience and Cell Death Research Groups, Medical School and Genetic Institute, Universidad Nacional de Colombia, Bogotá, Colombia., Arboleda H; Neuroscience and Cell Death Research Groups, Medical School and Genetic Institute, Universidad Nacional de Colombia, Bogotá, Colombia., Arboleda Bustos CE; Neuroscience and Cell Death Research Groups, Medical School and Genetic Institute, Universidad Nacional de Colombia, Bogotá, Colombia., Yearout D; Veterans Affairs Puget Sound Health Care System, Seattle, Washington, USA.; Department of Neurology, University of Washington, Seattle, Washington, USA., Barbosa MT; Behavioral and Cognitive Neurology Unit, Faculdade de Medicina, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.; Geriatric Medicine, Faculdade Ciências Médicas de Minas Gerais, Belo Horizonte, Brazil., Cardoso FEC; Movement Disorders Unit, Faculdade de Medicina, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil., Caramelli P; Behavioral and Cognitive Neurology Unit, Faculdade de Medicina, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil., Cunningham MCQ; Behavioral and Cognitive Neurology Unit, Faculdade de Medicina, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.; Movement Disorders Unit, Faculdade de Medicina, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil., Maia DP; Movement Disorders Unit, Faculdade de Medicina, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil., Lima-Costa MF; Instituto René Rachou da Fundação Oswaldo Cruz, Belo Horizonte, Brazil., Tarazona-Santos E; Department of Genetics, Ecology and Evolution, Institute of Biological Sciences, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil., Zabetian CP; Veterans Affairs Puget Sound Health Care System, Seattle, Washington, USA.; Department of Neurology, University of Washington, Seattle, Washington, USA., Thornton TA; Department of Biostatistics, University of Washington, Seattle, Washington, USA., O'Connor TD; Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, Maryland, USA.; Program in Health Equity and Population Health, University of Maryland School of Medicine, Baltimore, Maryland, USA.; Program in Personalized and Genomic Medicine, University of Maryland School of Medicine, Baltimore, Maryland, USA.; Department of Medicine, University of Maryland School of Medicine, Baltimore, Maryland, USA., Mata IF; Lerner Research Institute, Genomic Medicine, Cleveland Clinic, Cleveland, Ohio, USA.

Publikováno v: Movement disorders : official journal of the Movement Disorder Society [Mov Disord] 2023 Sep; Vol. 38 (9), pp. 1625-1635. Date of Electronic Publication: 2023 Jul 20.

Polygenic risk prediction and SNCA haplotype analysis in a Latino Parkinson's disease cohort.

Autor: Loesch DP; Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, MD, USA; Program in Personalized and Genomic Medicine, University of Maryland School of Medicine, Baltimore, MD, USA; Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA., Horimoto ARVR; Department of Biostatistics, University of Washington, Seattle, WA, USA., Sarihan EI; Lerner Research Institute, Genomic Medicine, Cleveland Clinic, Cleveland, OH, USA., Inca-Martinez M; Lerner Research Institute, Genomic Medicine, Cleveland Clinic, Cleveland, OH, USA., Mason E; Lerner Research Institute, Genomic Medicine, Cleveland Clinic, Cleveland, OH, USA., Cornejo-Olivas M; Neurogenetics Research Center, Instituto Nacional de Ciencias Neurologicas, Lima, Peru; Center for Global Health, Universidad Peruana Cayetano Heredia, Lima, Peru., Torres L; Movement Disorders Unit, Instituto Nacional de Ciencias Neurologicas, Lima, Peru; School of Medicine, Universidad Nacional Mayor de San Marcos, Lima, Peru., Mazzetti P; Neurogenetics Research Center, Instituto Nacional de Ciencias Neurologicas, Lima, Peru; School of Medicine, Universidad Nacional Mayor de San Marcos, Lima, Peru., Cosentino C; Movement Disorders Unit, Instituto Nacional de Ciencias Neurologicas, Lima, Peru; School of Medicine, Universidad Nacional Mayor de San Marcos, Lima, Peru., Sarapura-Castro E; Neurogenetics Research Center, Instituto Nacional de Ciencias Neurologicas, Lima, Peru., Rivera-Valdivia A; Neurogenetics Research Center, Instituto Nacional de Ciencias Neurologicas, Lima, Peru., Medina AC; Universidad Nacional del Altiplano, Puno, Peru., Dieguez E; Neurology Institute, Universidad de la República, Montevideo, Uruguay., Raggio V; Department of Genetics, Facultad de Medicina, Universidad de la República, Montevideo, Uruguay., Lescano A; Department of Genetics, Facultad de Medicina, Universidad de la República, Montevideo, Uruguay., Tumas V; Ribeirão Preto Medical School, Universidade de São Paulo, Ribeirão Preto, Brazil., Borges V; Movement Disorders Unit, Department of Neurology and Neurosurgery, Universidade Federal de São Paulo, São Paulo, Brazil., Ferraz HB; Movement Disorders Unit, Department of Neurology and Neurosurgery, Universidade Federal de São Paulo, São Paulo, Brazil., Rieder CR; Departamento de Neurologia, Universidade Federal de Ciências da Saúde de Porto Alegre, Porto Alegre, Brazil., Schumacher-Schuh A; Serviço de Neurologia, Hospital de Clínicas de Porto Alegre, Porto Alegre, Brazil; Departamento de Farmacologia, Universidade Federal do Rio Grande do Sul, Brazil., Santos-Lobato BL; Instituto de Ciências da Saúde, Universidade Federal do Pará, Belém, Brazil., Velez-Pardo C; Neuroscience Research Group, Medical Research Institute, Faculty of Medicine, Universidad de Antioquia (UdeA), Medellín, Antioquia, Colombia., Jimenez-Del-Rio M; Neuroscience Research Group, Medical Research Institute, Faculty of Medicine, Universidad de Antioquia (UdeA), Medellín, Antioquia, Colombia., Lopera F; Neuroscience Research Group, Medical Research Institute, Faculty of Medicine, Universidad de Antioquia (UdeA), Medellín, Antioquia, Colombia., Moreno S; Neuroscience Research Group, Medical Research Institute, Faculty of Medicine, Universidad de Antioquia (UdeA), Medellín, Antioquia, Colombia., Chana-Cuevas P; CETRAM, Facultad de ciencias Medicas, Universidad de Santiago de Chile, Chile., Fernandez W; Neuroscience and Cell Death Research Groups, Medical School and Genetic Institute, Universidad Nacional de Colombia, Bogotá, Colombia., Arboleda G; Neuroscience and Cell Death Research Groups, Medical School and Genetic Institute, Universidad Nacional de Colombia, Bogotá, Colombia., Arboleda H; Neuroscience and Cell Death Research Groups, Medical School and Genetic Institute, Universidad Nacional de Colombia, Bogotá, Colombia., Arboleda-Bustos CE; Neuroscience and Cell Death Research Groups, Medical School and Genetic Institute, Universidad Nacional de Colombia, Bogotá, Colombia., Yearout D; Veterans Affairs Puget Sound Health Care System, Seattle, WA, USA; Department of Neurology, University of Washington, Seattle, WA, USA., Zabetian CP; Veterans Affairs Puget Sound Health Care System, Seattle, WA, USA; Department of Neurology, University of Washington, Seattle, WA, USA., Thornton TA; Department of Biostatistics, University of Washington, Seattle, WA, USA., Mata IF; Lerner Research Institute, Genomic Medicine, Cleveland Clinic, Cleveland, OH, USA; Veterans Affairs Puget Sound Health Care System, Seattle, WA, USA; Department of Neurology, University of Washington, Seattle, WA, USA. Electronic address: matai@ccf.org., O'Connor TD; Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, MD, USA; Program in Personalized and Genomic Medicine, University of Maryland School of Medicine, Baltimore, MD, USA; Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA. Electronic address: timothydoconnor@gmail.com.

Publikováno v: Parkinsonism & related disorders [Parkinsonism Relat Disord] 2022 Sep; Vol. 102, pp. 7-15. Date of Electronic Publication: 2022 Jun 18.

Genome-Wide Analysis of Copy Number Variation in Latin American Parkinson's Disease Patients.

Autor: Sarihan EI; Lerner Research Institute, Genomic Medicine, Cleveland Clinic, Cleveland, Ohio, USA., Pérez-Palma E; Lerner Research Institute, Genomic Medicine, Cleveland Clinic, Cleveland, Ohio, USA., Niestroj LM; Cologne Center for Genomics, University of Cologne, Cologne, Germany., Loesch D; Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, Maryland, USA.; Program in Personalized and Genomic Medicine, University of Maryland School of Medicine, Baltimore, Maryland, USA.; Department of Medicine, University of Maryland School of Medicine, Baltimore, Maryland, USA., Inca-Martinez M; Lerner Research Institute, Genomic Medicine, Cleveland Clinic, Cleveland, Ohio, USA., Horimoto ARVR; Division of Medical Genetics, Department of Medicine, University of Washington, Seattle, Washington, USA., Cornejo-Olivas M; Neurogenetics Research Center, Instituto Nacional de Ciencias Neurologicas, Lima, Peru.; Center for Global Health, Universidad Peruana Cayetano Heredia, Lima, Peru., Torres L; Movement Disorders Unit, Instituto Nacional de Ciencias Neurologicas, Lima, Peru.; School of Medicine, Universidad Nacional Mayor de San Marcos, Lima, Peru., Mazzetti P; Neurogenetics Research Center, Instituto Nacional de Ciencias Neurologicas, Lima, Peru.; School of Medicine, Universidad Nacional Mayor de San Marcos, Lima, Peru., Cosentino C; Movement Disorders Unit, Instituto Nacional de Ciencias Neurologicas, Lima, Peru.; School of Medicine, Universidad Nacional Mayor de San Marcos, Lima, Peru., Sarapura-Castro E; Neurogenetics Research Center, Instituto Nacional de Ciencias Neurologicas, Lima, Peru., Rivera-Valdivia A; Neurogenetics Research Center, Instituto Nacional de Ciencias Neurologicas, Lima, Peru., Dieguez E; Neurology Institute, Universidad de la República, Montevideo, Uruguay., Raggio V; Department of Genetics, Facultad de Medicina, Universidad de la República, Montevideo, Uruguay., Lescano A; Neurology Institute, Universidad de la República, Montevideo, Uruguay., Tumas V; Ribeirão Preto Medical School, Universidade de São Paulo, Ribeirão Preto, Brazil., Borges V; Movement Disorders Unit, Department of Neurology and Neurosurgery, Universidade Federal de São Paulo, São Paulo, Brazil., Ferraz HB; Movement Disorders Unit, Department of Neurology and Neurosurgery, Universidade Federal de São Paulo, São Paulo, Brazil., Rieder CR; Departamento de Neurologia, Universidade Federal de Ciências da Saúde de Porto Alegre, Porto Alegre, Brazil., Schumacher-Schuh AF; Serviço de Neurologia, Hospital de Clínicas de Porto Alegre and Departamento de Farmacologia, Universidade Federal do Rio Grande do Su, Porto Alegre, Brazil., Santos-Lobato BL; Instituto de Ciências da Saúde, Universidade Federal do Pará, Belém, Brazil., Velez-Pardo C; Neuroscience Research Group, Medical Research Institute, Faculty of Medicine, Universidad de Antioquia (UdeA), Medellín, Colombia., Jimenez-Del-Rio M; Neuroscience Research Group, Medical Research Institute, Faculty of Medicine, Universidad de Antioquia (UdeA), Medellín, Colombia., Lopera F; Neuroscience Research Group, Medical Research Institute, Faculty of Medicine, Universidad de Antioquia (UdeA), Medellín, Colombia., Moreno S; Neuroscience Research Group, Medical Research Institute, Faculty of Medicine, Universidad de Antioquia (UdeA), Medellín, Colombia., Chana-Cuevas P; CETRAM, Facultad de Ciencias Medicas, Universidad de Santiago de Chile, Santiago de Chile, Chile., Fernandez W; Neuroscience and Cell Death Research Groups, Medical School and Genetic Institute, Universidad Nacional de Colombia, Bogotá, Colombia., Arboleda G; Neuroscience and Cell Death Research Groups, Medical School and Genetic Institute, Universidad Nacional de Colombia, Bogotá, Colombia., Arboleda H; Neuroscience and Cell Death Research Groups, Medical School and Genetic Institute, Universidad Nacional de Colombia, Bogotá, Colombia., Arboleda-Bustos CE; Neuroscience and Cell Death Research Groups, Medical School and Genetic Institute, Universidad Nacional de Colombia, Bogotá, Colombia., Yearout D; Veterans Affairs Puget Sound Health Care System, Seattle, Washington, USA.; Department of Neurology, University of Washington, Seattle, Washington, USA., Zabetian CP; Veterans Affairs Puget Sound Health Care System, Seattle, Washington, USA.; Department of Neurology, University of Washington, Seattle, Washington, USA., Thornton TA; Department of Biostatistics, University of Washington, Seattle, Washington, USA., O'Connor TD; Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, Maryland, USA.; Program in Personalized and Genomic Medicine, University of Maryland School of Medicine, Baltimore, Maryland, USA.; Department of Medicine, University of Maryland School of Medicine, Baltimore, Maryland, USA., Lal D; Lerner Research Institute, Genomic Medicine, Cleveland Clinic, Cleveland, Ohio, USA.; Cologne Center for Genomics, University of Cologne, Cologne, Germany.; Stanley Center for Psychiatric Research, Broad Institute of MIT & Harvard, Cambridge, Massachusetts, USA.; Epilepsy Center & Department of Neurology, Neurological Institute, Cleveland Clinic, Cleveland, Ohio, USA., Mata IF; Lerner Research Institute, Genomic Medicine, Cleveland Clinic, Cleveland, Ohio, USA.; Veterans Affairs Puget Sound Health Care System, Seattle, Washington, USA.; Department of Neurology, University of Washington, Seattle, Washington, USA.

Publikováno v: Movement disorders : official journal of the Movement Disorder Society [Mov Disord] 2021 Feb; Vol. 36 (2), pp. 434-441. Date of Electronic Publication: 2020 Nov 05.