Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Sariah J. Allen"'
Autor:
Quynh T. Tran, Alex Breuer, Tong Lin, Ruth Tatevossian, Sariah J. Allen, Michael Clay, Larissa V. Furtado, Mark Chen, Dale Hedges, Tylman Michael, Giles Robinson, Paul Northcott, Amar Gajjar, Elizabeth Azzato, Sheila Shurtleff, David W. Ellison, Stanley Pounds, Brent A. Orr
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-12 (2024)
Abstract As part of the advancement in therapeutic decision-making for brain tumor patients at St. Jude Children’s Research Hospital (SJCRH), we developed three robust classifiers, a deep learning neural network (NN), k-nearest neighbor (kNN), and
Externí odkaz:
https://doaj.org/article/04b24c66871347abb0fb60d227703a96
Autor:
Sasi Arunachalam, Karol Szlachta, Samuel W. Brady, Xiaotu Ma, Bensheng Ju, Bridget Shaner, Heather L. Mulder, John Easton, Benjamin J. Raphael, Matthew Myers, Christopher Tinkle, Sariah J. Allen, Brent A. Orr, Cynthia J. Wetmore, Suzanne J. Baker, Jinghui Zhang
Publikováno v:
Acta Neuropathologica Communications, Vol 10, Iss 1, Pp 1-14 (2022)
Abstract The majority of diffuse midline gliomas, H3 K27-altered (DMG-H3 K27-a), are infiltrating pediatric brain tumors that arise in the pons with no effective treatment. To understand how clonal evolution contributes to the tumor’s invasive spre
Externí odkaz:
https://doaj.org/article/02dac622bfc94b37b1ee8e53187e1be1
Autor:
Tara T. Doucet-O’Hare, Brianna L. DiSanza, Catherine DeMarino, Abigail L. Atkinson, Jared S. Rosenblum, Lisa J. Henderson, Kory R. Johnson, Jeffrey Kowalak, Marta Garcia-Montojo, Sariah J. Allen, Brent A. Orr, Mariarita Santi, Tongguang Wang, Saeed Fathi, Myoung Hwa Lee, Kevon Sampson, Wenxue Li, Zhengping Zhuang, Avindra Nath
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Atypical Teratoid Rhabdoid Tumor (AT/RT) is a rare pediatric central nervous system cancer often characterized by deletion or mutation of SMARCB1, a tumor suppressor gene. In this study, we found that SMARCB1 regulates Human Endogenous Retro
Externí odkaz:
https://doaj.org/article/b606f3bbb7b5473bafc41a2148c765eb
Autor:
Norman L. Lehman, Aisulu Usubalieva, Tong Lin, Sariah J. Allen, Quynh T. Tran, Bret C. Mobley, Roger E. McLendon, Matthew J. Schniederjan, Maria-Magdalena Georgescu, Marta Couce, Mohanpal S. Dulai, Jack M. Raisanen, Mousa Al Abbadi, Cheryl A. Palmer, Eyas M. Hattab, Brent A. Orr
Publikováno v:
Acta Neuropathologica Communications, Vol 7, Iss 1, Pp 1-11 (2019)
Abstract Astroblastoma (AB) is a rare CNS tumor demonstrating abundant astroblastomatous pseudorosettes. Its molecular features have not been comprehensively studied and its status as a tumor entity is controversial. We analyzed a cohort of 27 histol
Externí odkaz:
https://doaj.org/article/efefe643d23d4e53b9215d6a24653c30
Autor:
Jeffrey A. Rubens, Eric H. Raabe, Charles G. Eberhart, Barbara S. Slusher, Brent A. Orr, Harpreet Kaur, Allison R. Hanaford, Sariah J. Allen, Antoinette Price, Jesse Alt, Brad Poore, Sabrina Z. Wang
Formal synergy studies with DON and carboplatin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41fe3b4bbe4da4050c2840e5bec500e2
https://doi.org/10.1158/1078-0432.22474227.v1
https://doi.org/10.1158/1078-0432.22474227.v1
Autor:
Jeffrey A. Rubens, Eric H. Raabe, Charles G. Eberhart, Barbara S. Slusher, Brent A. Orr, Harpreet Kaur, Allison R. Hanaford, Sariah J. Allen, Antoinette Price, Jesse Alt, Brad Poore, Sabrina Z. Wang
Purpose:Atypical teratoid/rhabdoid tumors (AT/RT) are aggressive infantile brain tumors with poor survival. Recent advancements have highlighted significant molecular heterogeneity in AT/RT with an aggressive subgroup featuring overexpression of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b28cb0c383e6de4edc883717072254d
https://doi.org/10.1158/1078-0432.c.6528729.v1
https://doi.org/10.1158/1078-0432.c.6528729.v1
Autor:
Nitin R. Wadhwani, Jacqueline A. Brosnan-Cashman, Dima Hamideh, Marcus Matsushita, Hussein Alnajar, Fausto J. Rodriguez, Milad Webb, Alicia Rodríguez-Velasco, Leonidas D. Arvanitis, Caterina Giannini, Liam Chen, Brent A. Orr, Sariah J. Allen, Abeer Tabbarah, Christopher M. Heaphy, John R. Barber, Liqun Jiang, Sandra Camelo-Piragua, M. Adelita Vizcaino
Publikováno v:
Brain Pathology. 29:126-140
Anaplasia may be identified in a subset of tumors with a presumed pilocytic astrocytoma (PA) component or piloid features, which may be associated with aggressive behavior, but the biologic basis of this change remains unclear. Fifty-seven resections
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22494af2441f4c5faf83bcbc6feb2eb8
https://doi.org/10.1111/bpa.12646
https://doi.org/10.1111/bpa.12646
Publikováno v:
Journal of virology. 93(10)
The herpes simplex virus (HSV-1) latency-associated transcript (LAT) has been shown to inhibit apoptosis via inhibiting activation of proapoptotic caspases. However, the mechanism of LAT control of apoptosis is unclear, because LAT is not known to en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e853b346bc1ef32dd25fa5aa72e603b
https://pubmed.ncbi.nlm.nih.gov/30814286
https://pubmed.ncbi.nlm.nih.gov/30814286
Autor:
Sariah J. Allen, Behrooz G. Sharifi, Kevin R. Mott, Yasamin N. Ghiasi, Homayon Ghiasi, Omid Akbari, Mandana Zandian, Hadi Maazi, Harry H. Matundan, David M. Underhill
Publikováno v:
Immunobiology. 220:518-524
Recently, we have reported that CD8α(+) DCs, rather than CD8(+) T cells, are involved in the establishment and maintenance of HSV-1 latency in the trigeminal ganglia (TG) of ocularly infected mice. In the current study, we investigated whether simil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a38b5854f49ec7446074855859197387
https://doi.org/10.1016/j.imbio.2014.10.019
https://doi.org/10.1016/j.imbio.2014.10.019
Publikováno v:
Journal of Virology. 87:12102-12109
We have reported previously that ocular infection of different strains of mice with recombinant herpes simplex virus 1 (HSV-1) constitutively expressing interleukin-2 (IL-2) provokes central nervous system (CNS) demyelination and optic neuropathy, as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e9ae2be0ef258570315a0ffb74e25d1
https://doi.org/10.1128/jvi.02241-13
https://doi.org/10.1128/jvi.02241-13