Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Sariah A. Kell"'
Autor:
Holger Kanzler, John D. Campbell, Robert Milley, Atul Sathe, Melissa A. Kachura, Sariah A. Kell, Robert L. Coffman, Brian E. Hall, Carlo Calacsan, Gary Ott, Radwan Kiwan, Colin Hickle
Publikováno v:
The Journal of Immunology. 196:284-297
Nanoparticulate delivery systems for vaccine adjuvants, designed to enhance targeting of secondary lymphoid organs and activation of APCs, have shown substantial promise for enhanced immunopotentiation. We investigated the adjuvant activity of synthe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f59d57512806485ab21bd54fc166dc94
https://doi.org/10.4049/jimmunol.1501903
https://doi.org/10.4049/jimmunol.1501903
Autor:
Paula Traquina, John D. Campbell, Melissa A. Kachura, Alex Renn, Sariah A. Kell, Robert L. Coffman
Publikováno v:
International immunopharmacology. 66
CpG-motif-containing oligodeoxynucleotides (CpG-ODN) activate innate immunity through Toll-Like Receptor (TLR) 9 signaling and generate local immune responses when delivered directly to the lung. Herein we describe pharmacological studies in mice, cy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cb049bd67c73afaf7de46bed98566fa
https://pubmed.ncbi.nlm.nih.gov/30502651
https://pubmed.ncbi.nlm.nih.gov/30502651
Autor:
Clifford Wong, Albert Candia, Sariah A. Kell, Ian Robinson, Simone Floettmann, Jeremy A. Lum, John D. Campbell, Edith M. Hessel, Mark McHale, Stephen Delaney, Rainard Fuhr, John Bell, Sam Jackson, David J. Keeling, Paula Traquina, Robert L. Coffman
Publikováno v:
Clinical pharmacology and therapeutics. 104(2)
Current asthma treatments address symptoms rather than the underlying disease pathophysiology, a better understanding of which has led to the identification of the Th2 high endotype. The activation of Toll-like receptors to induce Type I interferons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f197798ab957f6543d70e5bb0feb44c3
https://pubmed.ncbi.nlm.nih.gov/29134633
https://pubmed.ncbi.nlm.nih.gov/29134633
Autor:
Rosemary Sweetwood, Hugh Salamon, Cameron R. Cunningham, Sariah A. Kell, Edith M. Hessel, John D. Campbell, Robert L. Coffman, Clare M. Lloyd, Mabel Chu, Jeremy A. Lum, HM Kozy
Publikováno v:
Thorax. 69:565-573
Background CpG-containing oligodeoxynucleotides (CpG-ODNs) are potent inhibitors of T helper 2 mediated allergic airway disease in sensitised mice challenged with allergen. A single treatment has transient effects but a limited series of treatments h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea895acc17690de256da70fc74220138
https://doi.org/10.1136/thoraxjnl-2013-204605
https://doi.org/10.1136/thoraxjnl-2013-204605
Autor:
Jennifer O. Lizcano, Mabel Chu, Robert L. Coffman, Marsha Wills-Karp, Edith M. Hessel, Sariah A. Kell, Nancy S. Herman, Bonnie Chang
Publikováno v:
The Journal of Experimental Medicine
A single treatment with a CpG-containing immunostimulatory DNA sequence (ISS) given before allergen challenge can inhibit T helper type 2 cell (Th2)–mediated airway responses in animal models of allergic asthma; however, the mechanism of this inhib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8dde314086e64831996457d98fa3f570
https://doi.org/10.1084/jem.20050631
https://doi.org/10.1084/jem.20050631
Autor:
Brandon F. Keele, Kirk M. Druey, Sariah A. Kell, Emily A. Palenske, Gregory F. Burton, Denise L. Hampton, Tyler C. Thacker, Jacob D. Estes
Publikováno v:
The Journal of Immunology. 173:6169-6178
Follicular dendritic cells (FDCs) up-regulate the chemokine receptor CXCR4 on CD4 T cells, and a major subpopulation of germinal center (GC) T cells (CD4+CD57+), which are adjacent to FDCs in vivo, expresses high levels of CXCR4. We therefore reasone
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::184ef21439ec651dc911b860ede97026
https://doi.org/10.4049/jimmunol.173.10.6169
https://doi.org/10.4049/jimmunol.173.10.6169
Autor:
HM Kozy, Edith M. Hessel, Karen L. Fearon, Mark McHale, John D. Campbell, Holger Kanzler, John Bell, Sariah A. Kell, Robert L. Coffman, Mark Graham
Publikováno v:
C21. NEW TARGETS FOR ASTHMA THERAPY.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b7ae80b7537edf8ff968940733f9c549
https://doi.org/10.1164/ajrccm-conference.2011.183.1_meetingabstracts.a4077
https://doi.org/10.1164/ajrccm-conference.2011.183.1_meetingabstracts.a4077
Publikováno v:
C32. IMMUNE CELLULAR NETWORK IN LUNG INFLAMMATION.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4291f3f18482e75f7a3a189f46e90e67
https://doi.org/10.1164/ajrccm-conference.2009.179.1_meetingabstracts.a4288
https://doi.org/10.1164/ajrccm-conference.2009.179.1_meetingabstracts.a4288
Autor:
Edith M. Hessel, Holger Kanzler, M Kachura, M Biffen, Ja Lum, R Garrett-Young, HM Kozy, Mark McHale, Robert L. Coffman, A Sathe, Sariah A. Kell, John Bell, M Dymond
Publikováno v:
D33. ASTHMA THERAPEUTICS -- STUDIES IN ANIMAL MODELS.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::09c3c8ee6a0a9cfe9495be408e9897e0
https://doi.org/10.1164/ajrccm-conference.2009.179.1_meetingabstracts.a5721
https://doi.org/10.1164/ajrccm-conference.2009.179.1_meetingabstracts.a5721
Autor:
HM Kozy, R Garrett-Young, Clare M. Lloyd, John D. Campbell, Sariah A. Kell, Robert L. Coffman, Ja Lum, Martyn Foster, S. G. Trivedi, Edith M. Hessel
Publikováno v:
C30. INFLAMMATORY AND IMMUNOLOGICAL MODELS OF ASTHMA.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ad133ffe0e77f520562e4fd3abdb2eda
https://doi.org/10.1164/ajrccm-conference.2009.179.1_meetingabstracts.a4254
https://doi.org/10.1164/ajrccm-conference.2009.179.1_meetingabstracts.a4254