Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Sari Suzuki"'
Autor:
Yuta Seki, Yuki Miyasaka, Sari Suzuki, Kenta Wada, Shumpei P Yasuda, Kunie Matsuoka, Yasuhiro Ohshiba, Kentaro Endo, Rie Ishii, Hiroshi Shitara, Shin-Ichiro Kitajiri, Naomi Nakagata, Hirohide Takebayashi, Yoshiaki Kikkawa
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0183477 (2017)
An unconventional myosin encoded by the myosin VI gene (MYO6) contributes to hearing loss in humans. Homozygous mutations of MYO6 result in nonsyndromic profound congenital hearing loss, DFNB37. Kumamoto shaker/waltzer (ksv) mice harbor spontaneous m
Externí odkaz:
https://doaj.org/article/c1e4ee1bdd074964b8ea025c2bba01e6
Autor:
Kenta Wada, Yoshibumi Matsushima, Tomoki Tada, Sayaka Hasegawa, Yo Obara, Yasuhiro Yoshizawa, Gou Takahashi, Hiroshi Hiai, Midori Shimanuki, Sari Suzuki, Junichi Saitou, Naoki Yamamoto, Masumi Ichikawa, Kei Watanabe, Yoshiaki Kikkawa
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e111432 (2014)
Microphthalmia is a severe ocular disorder, and this condition is typically caused by mutations in transcription factors that are involved in eye development. Mice carrying mutations in these transcription factors would be useful tools for defining t
Externí odkaz:
https://doaj.org/article/06646f858edb4fc3a91f62cd2ce2d139
Autor:
Ruihua Dang, Daisuke Torigoe, Sari Suzuki, Yoshiaki Kikkawa, Kanako Moritoh, Nobuya Sasaki, Takashi Agui
Publikováno v:
PLoS ONE, Vol 6, Iss 10 (2011)
Externí odkaz:
https://doaj.org/article/fd88b2c74baa428b9cf2d30d59b0b218
Autor:
Ruihua Dang, Daisuke Torigoe, Sari Suzuki, Yoshiaki Kikkawa, Kanako Moritoh, Nobuya Sasaki, Takashi Agui
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e24086 (2011)
Hirschsprung disease (HSCR) is thought to result as a consequence of multiple gene interactions that modulate the ability of enteric neural crest cells to populate the developing gut. However, it remains unknown whether the single complete deletion o
Externí odkaz:
https://doaj.org/article/76cf50493cff4ac0b61af6a7de34d19f
Autor:
Shumpei P, Yasuda, Yuta, Seki, Sari, Suzuki, Yasuhiro, Ohshiba, Xuehan, Hou, Kunie, Matsuoka, Kenta, Wada, Hiroshi, Shitara, Yuki, Miyasaka, Yoshiaki, Kikkawa
Publikováno v:
Hearing research. 389
C57BL/6J mice have long been studied as a model of age-related hearing loss (ARHL). In C57BL/6J mice, ARHL begins in the high-frequency range at 3 months of age and spreads toward low frequencies by 10 months of age. We previously confirmed that c.75
Autor:
Shumpei P. Yasuda, Kunie Matsuoka, Hiroshi Shitara, Xuehan Hou, Kenta Wada, Yoshiaki Kikkawa, Yuki Miyasaka, Yuta Seki, Sari Suzuki, Yasuhiro Ohshiba
Publikováno v:
Hearing Research. 389:107926
C57BL/6J mice have long been studied as a model of age-related hearing loss (ARHL). In C57BL/6J mice, ARHL begins in the high-frequency range at 3 months of age and spreads toward low frequencies by 10 months of age. We previously confirmed that c.75
Autor:
Yasuhiro Ohshiba, Michinari Yokohama, Choji Taya, Takuya Ueda, Kazuhiro Okumura, Kunie Matsuoka, Sari Suzuki, Yuki Miyasaka, Yoshiaki Kikkawa, Masashi Ishikawa
Publikováno v:
Experimental Animals
The DBA/2J strain is a model for early-onset, progressive hearing loss in humans, as confirmed in the present study. DBA/2J mice showed progression of hearing loss to low-frequency sounds from ultrasonic-frequency sounds and profound hearing loss at
Autor:
Kei Watanabe, Kunie Matsuoka, Shumpei P. Yasuda, Yoshiaki Kikkawa, Yoshihiko Sagara, Ryo Kominami, Hiromichi Yonekawa, Yuki Miyasaka, Sari Suzuki, Hiroshi Shitara, Yasuhiro Ohshiba
Publikováno v:
Experimental Animals. 62:333-346
The waltzer (v) mouse mutant harbors a mutation in Cadherin 23 (Cdh23) and is a model for Usher syndrome type 1D, which is characterized by congenital deafness, vestibular dysfunction, and prepubertal onset of progressive retinitis pigmentosa. In mic
Autor:
Sari Suzuki, Yuki Miyasaka, Yoshihiro Noguchi, Kazuhiro Okumura, Kunie Matsuoka, Mao Ozaki, Yasuhiro Ohshiba, Yuta Seki, Hiromichi Yonekawa, Yoshiaki Kikkawa
Publikováno v:
Experimental Animals. 61:85-98
Hearing is a major factor in human quality of life. Mouse models are important tools for discovering the genes that are responsible for genetic hearing loss, and these models often allow the processes that regulate the onset of deafness in humans to
Autor:
Yasuhiro Ohshiba, Kazuhiro Okumura, Sari Suzuki, Yuta Seki, Toyoyuki Takada, Ken Kitamura, Sachi Yoshimoto, Yoshiaki Kikkawa, Hisashi Tokano, Ryo Kominami, Hiroshi Hibino, Hiromichi Yonekawa, Hiroshi Shitara, Choji Taya, Toshihiko Shiroishi, Yuki Miyasaka
Publikováno v:
Human molecular genetics. 25(10)
Most clinical reports have suggested that patients with congenital profound hearing loss have recessive mutations in deafness genes, whereas dominant alleles are associated with progressive hearing loss (PHL). Jackson shaker (Ush1gjs) is a mouse mode