Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Sari, Pennings"'
Autor:
Katy McLaughlin, Ilya M. Flyamer, John P. Thomson, Heidi K. Mjoseng, Ruchi Shukla, Iain Williamson, Graeme R. Grimes, Robert S. Illingworth, Ian R. Adams, Sari Pennings, Richard R. Meehan, Wendy A. Bickmore
Publikováno v:
Cell Reports, Vol 29, Iss 7, Pp 1974-1985.e6 (2019)
Summary: The DNA hypomethylation that occurs when embryonic stem cells (ESCs) are directed to the ground state of naive pluripotency by culturing in two small molecule inhibitors (2i) results in redistribution of polycomb (H3K27me3) away from its tar
Externí odkaz:
https://doaj.org/article/494966c0bb4449d6817be1b988d20ad1
Publikováno v:
Stem Cells International, Vol 2018 (2018)
Externí odkaz:
https://doaj.org/article/6f6a260b43b945039bfd8b9f83829be9
Publikováno v:
Stem Cells International, Vol 2018 (2018)
Heart development in mammals is followed by a postnatal decline in cell proliferation and cell renewal from stem cell populations. A better understanding of the developmental changes in cardiac microenvironments occurring during heart maturation will
Externí odkaz:
https://doaj.org/article/ca5332430f474ef59511c1b118fa9edd
Autor:
Markus F. Templin, Duncan Sproul, Donncha S. Dunican, Heidi K. Mjoseng, Bernard Ramsahoye, John P. Thomson, Ian R. Adams, Ruchi Shukla, Richard R. Meehan, Tuempong Wongtawan, Simon Kling, Sari Pennings, Fridolin Treindl
Publikováno v:
Nucleic Acids Research
Shukla, R, Mjoseng, H K, Thomson, J, Kling, S, Sproul, D, Dunican, D, Ramsahoye, B, Wongtawan, T, Treindl, F, Templin, M F, Adams, I, Pennings, S & Meehan, R 2020, ' Activation of transcription factor circuity in 2i-induced ground state pluripotency is independent of repressive global epigenetic landscapes ', Nucleic Acids Research . https://doi.org/10.1093/nar/gkaa529
Shukla, R, Mjoseng, H K, Thomson, J, Kling, S, Sproul, D, Dunican, D, Ramsahoye, B, Wongtawan, T, Treindl, F, Templin, M F, Adams, I, Pennings, S & Meehan, R 2020, ' Activation of transcription factor circuity in 2i-induced ground state pluripotency is independent of repressive global epigenetic landscapes ', Nucleic Acids Research . https://doi.org/10.1093/nar/gkaa529
Mouse embryonic stem cells (mESCs) cultured with MEK/ERK and GSK3β (2i) inhibitors transition to ground state pluripotency. Gene expression changes, redistribution of histone H3K27me3 profiles and global DNA hypomethylation are hallmarks of 2i expos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0a9e2191b9b510796e6054fc45296c9
http://europepmc.org/articles/PMC7641322
http://europepmc.org/articles/PMC7641322
Autor:
Sari Pennings, Robert S. Illingworth, Heidi K. Mjoseng, John P. Thomson, Iain Williamson, Wendy A. Bickmore, Ilya M. Flyamer, Katy A. Mclaughlin, Richard R. Meehan, Graeme R. Grimes, Ruchi Shukla, Ian R. Adams
Publikováno v:
Cell Reports, Vol 29, Iss 7, Pp 1974-1985.e6 (2019)
Cell Reports
Mclaughlin, K, Flyamer, I M, Thomson, J P, Mjoseng, H K, Shukla, R, Williamson, I, Grimes, G R, Illingworth, R S, Adams, I R, Pennings, S, Meehan, R R & Bickmore, W A 2019, ' DNA Methylation Directs Polycomb-Dependent 3D Genome Re-organization in Naive Pluripotency ', vol. 29, no. 7, pp. 1974-1985.e6 . https://doi.org/10.1016/j.celrep.2019.10.031
McLaughlin, K, Flyamer, I M, Thomson, J P, Mjoseng, H K, Shukla, R, Williamson, I, Grimes, G R, Illingworth, R S, Adams, I R, Pennings, S, Meehan, R R & Bickmore, W A 2019, ' DNA Methylation Directs Polycomb-Dependent 3D Genome Re-organization in Naive Pluripotency ', Cell Reports, vol. 29, no. 7, pp. 1974-1985.e6 . https://doi.org/10.1016/j.celrep.2019.10.031, https://doi.org/10.1016/j.celrep.2019.10.031
Cell Reports
Mclaughlin, K, Flyamer, I M, Thomson, J P, Mjoseng, H K, Shukla, R, Williamson, I, Grimes, G R, Illingworth, R S, Adams, I R, Pennings, S, Meehan, R R & Bickmore, W A 2019, ' DNA Methylation Directs Polycomb-Dependent 3D Genome Re-organization in Naive Pluripotency ', vol. 29, no. 7, pp. 1974-1985.e6 . https://doi.org/10.1016/j.celrep.2019.10.031
McLaughlin, K, Flyamer, I M, Thomson, J P, Mjoseng, H K, Shukla, R, Williamson, I, Grimes, G R, Illingworth, R S, Adams, I R, Pennings, S, Meehan, R R & Bickmore, W A 2019, ' DNA Methylation Directs Polycomb-Dependent 3D Genome Re-organization in Naive Pluripotency ', Cell Reports, vol. 29, no. 7, pp. 1974-1985.e6 . https://doi.org/10.1016/j.celrep.2019.10.031, https://doi.org/10.1016/j.celrep.2019.10.031
Summary The DNA hypomethylation that occurs when embryonic stem cells (ESCs) are directed to the ground state of naive pluripotency by culturing in two small molecule inhibitors (2i) results in redistribution of polycomb (H3K27me3) away from its targ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4118aa557286e9e9599c93a2d84fc77
http://www.sciencedirect.com/science/article/pii/S2211124719313312
http://www.sciencedirect.com/science/article/pii/S2211124719313312
Autor:
Heidi K. Mjoseng, Ian R. Adams, Ruchi Shukla, Ilya M. Flyamer, Graeme R. Grimes, Robert S. Illingworth, Iain Williamson, Katy A. Mclaughlin, Sari Pennings, Wendy A. Bickmore, Richard R. Meehan, John P. Thomson
The DNA hypomethylation that occurs when embryonic stem cells (ESCs) are directed to the ground state of naive pluripotency by culturing in 2i conditions results in redistribution of polycomb (H3K27me3) away from its target loci. Here we demonstrate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d7141cf2dceb86971519eae30e886b70
https://doi.org/10.1101/527309
https://doi.org/10.1101/527309
Autor:
Petchroi Petchreing, Ailsa Revuelta, Nur Annies Abd Hadi, Raffaele Ottaviano, Sari Pennings, Katy A. Mclaughlin, Richard R. Meehan
Publikováno v:
Pennings, S, Revuelta, A, Mclaughlin, K A, Abd Hadi, N A, Petchreing, P, Ottaviano, R & Meehan, R R 2019, Dynamics and Mechanisms of DNA Methylation Reprogramming . in Epigenetics and Regeneration . Elsevier, pp. 19-45 . https://doi.org/10.1016/B978-0-12-814879-2.00002-9
The molecular profiling of DNA and histone modifications in multiple in vitro and in vivo systems has enabled unique explorations of potential epigenetic regulatory pathways. An important question is whether these epigenetic pathways drive developmen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df4780db983fcb98cbaffe19ec6e8e09
https://doi.org/10.1016/b978-0-12-814879-2.00002-9
https://doi.org/10.1016/b978-0-12-814879-2.00002-9
Autor:
Slimane Ait-Si-Ali, Sonia Albini, Gil Atzmon, Stephen F. Badylak, C.J. Barnstable, Beatrice Biferali, Nicolò Caporale, Zhaoyi Chen, Fulvio Chiacchiera, James A. Coffman, William D’Angelo, Wendy Dean, Jonas Eriksson, Agustín F. Fernández, Mario F. Fraga, Sònia Guil, Danielle Gutman, Nur Annies Abd Hadi, Courtney W. Hanna, Nataša Josipović, Lisa M. Julian, Antonello Mai, Luca Marelli, Ryan L. McCarthy, Katy A. McLaughlin, Richard R. Meehan, Chiara Mozzetta, Dario Nicetto, Cristina Oliveira-Mateos, Raffaele Ottaviano, Christina Pagiatakis, Daniela Palacios, Roberto Papait, Argyris Papantonis, Sari Pennings, Raúl F. Pérez, Petchroi Petchreing, Adam Pietrobon, E.Y. Popova, Ailsa Revuelta, Anaís Sánchez-Castillo, Pablo Santamarina, Simone Serio, William L. Stanford, Giulia Stazi, Giuseppe Testa, Sergio Valente, Maria Teresa Viscomi, Vlada Zakharova, Kenneth S. Zaret, Clemens Zwergel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dffe83fbddb4bb3ca80a99b197b34ccb
https://doi.org/10.1016/b978-0-12-814879-2.09994-5
https://doi.org/10.1016/b978-0-12-814879-2.09994-5
Publikováno v:
DNA Methylation Protocols. Series Methods in Molecular Biology
Tost J. DNA Methylation Protocols. Series Methods in Molecular Biology, 1708 (3ème ed), Humana Press, NY, pp.59-80, 2018, Methods in Molecular Biology, 1064-3745. ⟨10.1007/978-1-4939-7481-8_4⟩
Tost J. DNA Methylation Protocols. Series Methods in Molecular Biology, 1708, Humana Press, NY, pp.59-80, 2018, 1064-3745. ⟨10.1007/978-1-4939-7481-8_4⟩
Methods in Molecular Biology ISBN: 9781493974795
Tost J. DNA Methylation Protocols. Series Methods in Molecular Biology, 1708 (3ème ed), Humana Press, NY, pp.59-80, 2018, Methods in Molecular Biology, 1064-3745. ⟨10.1007/978-1-4939-7481-8_4⟩
Tost J. DNA Methylation Protocols. Series Methods in Molecular Biology, 1708, Humana Press, NY, pp.59-80, 2018, 1064-3745. ⟨10.1007/978-1-4939-7481-8_4⟩
Methods in Molecular Biology ISBN: 9781493974795
International audience; Immunostaining is widely used in cell biology for the in situ detection of proteins in fixed cells. The method is based on the specificity of antibodies for recognizing and binding to a selected target, combined with immunolab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::107bafafcd567c16e639d2a014175db3
https://hal.archives-ouvertes.fr/hal-02238169
https://hal.archives-ouvertes.fr/hal-02238169
Publikováno v:
Stem Cells International
Pennings, S, Liu, K J & Qian, H 2018, ' The Stem Cell Niche: Interactions between Stem Cells and Their Environment ', Stem Cells International . https://doi.org/10.1155/2018/4879379
Stem Cells International, Vol 2018 (2018)
Pennings, S, Liu, K J & Qian, H 2018, ' The Stem Cell Niche : Interactions between Stem Cells and Their Environment ', Stem cells international . https://doi.org/10.1155/2018/4879379
Pennings, S, Liu, K J & Qian, H 2018, ' The Stem Cell Niche: Interactions between Stem Cells and Their Environment ', Stem Cells International . https://doi.org/10.1155/2018/4879379
Stem Cells International, Vol 2018 (2018)
Pennings, S, Liu, K J & Qian, H 2018, ' The Stem Cell Niche : Interactions between Stem Cells and Their Environment ', Stem cells international . https://doi.org/10.1155/2018/4879379
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0aae694305f998ac5080d0137a23eff5
http://europepmc.org/articles/PMC6204189
http://europepmc.org/articles/PMC6204189