Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Sari, Mattila"'
Autor:
Johannes Cairns, Katariina Koskinen, Reetta Penttinen, Tommi Patinen, Anna Hartikainen, Roosa Jokela, Liisa Ruusulehto, Sirja Viitamäki, Sari Mattila, Teppo Hiltunen, Matti Jalasvuori
Publikováno v:
mSystems, Vol 3, Iss 5 (2018)
ABSTRACT Mobile genetic elements such as conjugative plasmids are responsible for antibiotic resistance phenotypes in many bacterial pathogens. The ability to conjugate, the presence of antibiotics, and ecological interactions all have a notable role
Externí odkaz:
https://doaj.org/article/df4d0e9000f64518b8293dc5f5b962ec
Autor:
Sari, Mattila, Pirjo, Merilahti, Sarah, Wazir, Tania, Quirin, Mirko M, Maksimainen, Yuezhou, Zhang, Henri, Xhaard, Lari, Lehtiö, Tero, Ahola
Publikováno v:
Antimicrob Agents Chemother
Alphaviruses are positive-strand RNA viruses causing febrile disease. Macrodomain-containing proteins, involved in ADP-ribose-mediated signaling, are encoded by both host cells and several virus groups, including alphaviruses. In this study, compound
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0126094 (2015)
Virus capsids mediate the transfer of viral genetic information from one cell to another, thus the origin of the first viruses arguably coincides with the origin of the viral capsid. Capsid genes are evolutionarily ancient and their emergence potenti
Externí odkaz:
https://doaj.org/article/e35811973ca9442bbb6505e67eb17481
Publikováno v:
Gut Microbes
The possibility to modify gut bacterial flora has become an important goal, and various approaches are used to achieve desirable communities. However, the genetic engineering of existing microbes in the gut, which are already compatible with the rest
Autor:
Jaana K. H. Bamford, Teppo Hiltunen, Ville Ojala, Matti Jalasvuori, Sari Mattila, Ville Hoikkala
Publikováno v:
Future Microbiology. 11:999-1009
Aim: To investigate the potential evolutionary obstacles in the sustainable therapeutic use of plasmid-dependent phages to control the clinically important conjugative plasmid-mediated dissemination of antibiotic resistance genes to pathogenic bacter
Autor:
Johannes, Cairns, Katariina, Koskinen, Reetta, Penttinen, Tommi, Patinen, Anna, Hartikainen, Roosa, Jokela, Liisa, Ruusulehto, Sirja, Viitamäki, Sari, Mattila, Teppo, Hiltunen, Matti, Jalasvuori
Publikováno v:
mSystems, Vol 3, Iss 5 (2018)
mSystems
mSystems
Bacterial antibiotic resistance is often a part of mobile genetic elements that move from one bacterium to another. By interfering with the horizontal movement and the maintenance of these elements, it is possible to remove the resistance from the po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::a1a74730e16232c7b195546636aa9e9a
http://hdl.handle.net/10138/247105
http://hdl.handle.net/10138/247105
Autor:
Matti Jalasvuori, Timo Tuononen, Sari Mattila, Teppo Hiltunen, Ville Ojala, Pilvi Ruotsalainen
Publikováno v:
The Journal of antibiotics. 70(6)
Conjugative ESBL plasmids differ in their potential to rescue susceptible bacteria via horizontal gene transfer in lethal antibiotic concentrations
Publikováno v:
Journal of Global Antimicrobial Resistance. 2:198-200
β-Lactams are a commonly used class of bactericidal antibiotics. The number of β-lactam-resistant pathogens is constantly increasing in hospitals around the world. Interestingly, most of the β-lactam-resistant bacteria carry mobile genetic element
On-Demand Isolation of Bacteriophages Against Drug-Resistant Bacteria for Personalized Phage Therapy
Publikováno v:
Frontiers in Microbiology, Vol 6 (2015)
Frontiers in Microbiology
Frontiers in Microbiology
Bacteriophages are bacterial viruses, capable of killing even multi-drug resistant bacterial cells. For this reason, therapeutic use of phages is considered as a possible alternative to conventional antibiotics. However, phages are very host specific
Publikováno v:
The Journal of general virology. 96(Pt 2)
PRD1 is a Gram-negative bacteria infecting complex tailless icosahedral virus with an inner membrane. This type virus of the family Tectiviridae contains at least 18 structural protein species, of which several are membrane associated. Vertices of th