Zobrazeno 1 - 10
of 427
pro vyhledávání: '"Sargramostim"'
Autor:
Iván Oterino‐Moreira, María‐Jesús Linares‐Asensio, Sira Sanz‐Márquez, Montserrat Pérez‐Encinas
Publikováno v:
The Clinical Respiratory Journal, Vol 17, Iss 10, Pp 1077-1081 (2023)
Abstract Introduction Autoimmune pulmonary alveolar proteinosis (aPAP) is a disease caused by IgG antibodies against granulocyte‐macrophage colony‐stimulating factor (GM‐CSF). Whole lung lavage (WLL) allows to remove the lipo‐proteinaceous ma
Externí odkaz:
https://doaj.org/article/c0856f6c3e284b949386edf93b0891c3
Autor:
Katherine E. Olson, Mai M. Abdelmoaty, Krista L. Namminga, Yaman Lu, Helen Obaro, Pamela Santamaria, R. Lee Mosley, Howard E. Gendelman
Publikováno v:
Translational Neurodegeneration, Vol 12, Iss 1, Pp 1-17 (2023)
Abstract Background The clinical utility and safety of sargramostim has previously been reported in cancer, acute radiation syndrome, autoimmune disease, inflammatory conditions, and Alzheimer’s disease. The safety, tolerability, and mechanisms of
Externí odkaz:
https://doaj.org/article/6aff7aaecbfb4f87a699e0984d9801ed
Autor:
Hillard M. Lazarus, Katherine Pitts, Tisha Wang, Elinor Lee, Elizabeth Buchbinder, Michael Dougan, David G. Armstrong, Robert Paine, Carolyn E. Ragsdale, Timothy Boyd, Edwin P. Rock, Robert Peter Gale
Publikováno v:
Frontiers in Immunology, Vol 13 (2023)
IntroductionEndogenous granulocyte-macrophage colony-stimulating factor (GM-CSF), identified by its ability to support differentiation of hematopoietic cells into several types of myeloid cells, is now known to support maturation and maintain the met
Externí odkaz:
https://doaj.org/article/628d7532ee3142388262f636c3a91400
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2022)
This review summarizes the structure and function of the alveolar unit, comprised of alveolar macrophage and epithelial cell types that work in tandem to respond to infection. Granulocyte-macrophage colony-stimulating factor (GM-CSF) helps to maintai
Externí odkaz:
https://doaj.org/article/fc50277cd6fc4a3d9d890cc2743d2d6e
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Autoantibodies to multiple cytokines have been identified and some, including antibodies against granulocyte-macrophage colony-stimulating factor (GM-CSF), have been associated with increased susceptibility to infection. High levels of GM-CSF autoant
Externí odkaz:
https://doaj.org/article/421e8c5a8d954e5abbc5404e63fbe51c
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
BackgroundSargramostim [recombinant human granulocyte-macrophage colony-stimulating factor (rhu GM-CSF)] was approved by US FDA in 1991 to accelerate bone marrow recovery in diverse settings of bone marrow failure and is designated on the list of FDA
Externí odkaz:
https://doaj.org/article/7672ca5256fd44b3aad228f016966cef
Autor:
Katherine E. Olson, Krista L. Namminga, Yaman Lu, Aaron D. Schwab, Mackenzie J. Thurston, Mai M. Abdelmoaty, Vikas Kumar, Melinda Wojtkiewicz, Helen Obaro, Pamela Santamaria, R. Lee Mosley, Howard E. Gendelman
Publikováno v:
EBioMedicine, Vol 67, Iss , Pp 103380- (2021)
Background: Neuroinflammation plays a pathogenic role in Parkinson's disease (PD). Immunotherapies that restore brain homeostasis can mitigate neurodegeneration by transforming T cell phenotypes. Sargramostim has gained considerable attention as an i
Externí odkaz:
https://doaj.org/article/42564ef1ed174676ac5a8c08781fbe1f
Akademický článek
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Autor:
Jaume Mora, Alicia Castañeda, Miguel A. Flores, Vicente Santa-María, Moira Garraus, Maite Gorostegui, Margarida Simao, Sara Perez-Jaume, Salvador Mañe
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Background: Treatment of HR-NB comprise induction, consolidation with autologous stem cell transplant (ASCT) followed by anti-GD2 immunotherapy and isotretinoin. Childrens Oncology Group and SIOPEN studies used dinutuximab and cytokines to treat pati
Externí odkaz:
https://doaj.org/article/5b3684de8e6544c5bc25907d5a0a15ca
Publikováno v:
Drug Design, Development and Therapy, Vol Volume 12, Pp 2025-2038 (2018)
Peng Chen,1,* Fuchao Chen,2,* Benhong Zhou1,3 1Department of Pharmacy, Renmin Hospital of Wuhan University, Wuhan, Hubei, 430060, People’s Republic of China; 2Department of Pharmacy, Dongfeng Hospital, Hubei University of Medicine, Shiyan, Hubei, 4
Externí odkaz:
https://doaj.org/article/06c33fa7044c496d897f7e29c580f445