Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Sargis Sedrakyan"'
Autor:
Hasmik Soloyan, Matthew Thornton, Valentina Villani, Patrick Khatchadourian, Paolo Cravedi, Andrea Angeletti, Brendan Grubbs, Roger De Filippo, Laura Perin, Sargis Sedrakyan
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-18 (2020)
Abstract Glomerular endothelial cells (GEC) are a crucial component of the glomerular physiology and their damage contributes to the progression of chronic kidney diseases. How GEC affect the pathology of Alport syndrome (AS) however, is unclear. We
Externí odkaz:
https://doaj.org/article/a65b9cc1a4f24bcc8215f165c1aea6a8
Autor:
Georgina Gyarmati, Urvi Nikhil Shroff, Audrey Izuhara, Xiaogang Hou, Stefano Da Sacco, Sargis Sedrakyan, Kevin V. Lemley, Kerstin Amann, Laura Perin, János Peti-Peterdi
Publikováno v:
JCI Insight, Vol 7, Iss 1 (2022)
Alport syndrome (AS) is a genetic disorder caused by mutations in type IV collagen that lead to defective glomerular basement membrane, glomerular filtration barrier (GFB) damage, and progressive chronic kidney disease. While the genetic basis of AS
Externí odkaz:
https://doaj.org/article/bd42a6b6676047dcb9c617b3480935cc
Publikováno v:
Frontiers in Medicine, Vol 8 (2021)
Kidney disease is characterized by loss of glomerular function with clinical manifestation of proteinuria. Identifying the cellular and molecular changes that lead to loss of protein in the urine is challenging due to the complexity of the filtration
Externí odkaz:
https://doaj.org/article/ed5b68a904544b88804db61d4a1bfdca
Autor:
Stefano Da Sacco, Kevin V Lemley, Sargis Sedrakyan, Ilenia Zanusso, Astgik Petrosyan, Janos Peti-Peterdi, James Burford, Roger E De Filippo, Laura Perin
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e81812 (2013)
Amniotic fluid is in continuity with multiple developing organ systems, including the kidney. Committed, but still stem-like cells from these organs may thus appear in amniotic fluid. We report having established for the first time a stem-like cell p
Externí odkaz:
https://doaj.org/article/d8ec7bd9f3b14f6da062530c581abef7
Autor:
Orquidea Garcia, Gianni Carraro, Gianluca Turcatel, Marisa Hall, Sargis Sedrakyan, Tyler Roche, Sue Buckley, Barbara Driscoll, Laura Perin, David Warburton
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e71679 (2013)
The potential for amniotic fluid stem cell (AFSC) treatment to inhibit the progression of fibrotic lung injury has not been described. We have previously demonstrated that AFSC can attenuate both acute and chronic-fibrotic kidney injury through modif
Externí odkaz:
https://doaj.org/article/3228f4ede88348e7a5ff1b03c474a4ab
Autor:
Laura Perin, Sargis Sedrakyan, Stefano Giuliani, Stefano Da Sacco, Gianni Carraro, Liron Shiri, Kevin V Lemley, Michael Rosol, Sam Wu, Anthony Atala, David Warburton, Roger E De Filippo
Publikováno v:
PLoS ONE, Vol 5, Iss 2, p e9357 (2010)
Acute Tubular Necrosis (ATN) causes severe damage to the kidney epithelial tubular cells and is often associated with severe renal dysfunction. Stem-cell based therapies may provide alternative approaches to treating of ATN. We have previously shown
Externí odkaz:
https://doaj.org/article/7e6d4c68565a4a6e9578ee83bdb989b1
Autor:
Astgik Petrosyan, Valentina Villani, Paola Aguiari, Matthew E. Thornton, Yizhou Wang, Alex Rajewski, Shengmei Zhou, Paolo Cravedi, Brendan H. Grubbs, Roger E. De Filippo, Sargis Sedrakyan, Kevin V. Lemley, Marie Csete, Stefano Da Sacco, Laura Perin
Publikováno v:
Advanced Science.
Autor:
Astgik Petrosyan, Valentina Villani, Paola Aguiari, Matthew Thornton, Zhou Shengmei, Brendan Grubbs, Marie Csete, Roger De Filippo, Kevin Lemley, Sargis Sedrakyan, Stefano Da Sacco, Laura Perin
Publikováno v:
Journal of Urology. 207
Autor:
Audrey K. Izuhara, Kerstin Amann, Kevin V. Lemley, Janos Peti-Peterdi, Urvi Nikhil Shroff, Georgina Gyarmati, Laura Perin, Stefano Da Sacco, Sargis Sedrakyan, Xiaogang Hou
Publikováno v:
JCI Insight
Alport syndrome (AS) is a genetic disorder caused by mutations in type IV collagen that lead to defective glomerular basement membrane, glomerular filtration barrier (GFB) damage, and progressive chronic kidney disease. While the genetic basis of AS
Publikováno v:
Frontiers in Medicine
Frontiers in Medicine, Vol 8 (2021)
Frontiers in Medicine, Vol 8 (2021)
Kidney disease is characterized by loss of glomerular function with clinical manifestation of proteinuria. Identifying the cellular and molecular changes that lead to loss of protein in the urine is challenging due to the complexity of the filtration