Zobrazeno 1 - 10
of 170
pro vyhledávání: '"Sareh Parangi"'
Autor:
Jeremy M. Quintana, Mikyung Kang, Huiyu Hu, Thomas S. C. Ng, Gregory R. Wojtkiewicz, Ella Scott, Sareh Parangi, Jan Schuemann, Ralph Weissleder, Miles A. Miller
Publikováno v:
ACS Central Science, Vol 10, Iss 7, Pp 1371-1382 (2024)
Externí odkaz:
https://doaj.org/article/c3f80e25bbe34e328ba277b41fad204a
Autor:
Youngsook Lucy Jung, Wenping Zhao, Ian Li, Dhawal Jain, Charles B. Epstein, Bradley E. Bernstein, Sareh Parangi, Richard Sherwood, Cassianne Robinson-Cohen, Yi-Hsiang Hsu, Peter J. Park, Michael Mannstadt
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract In all terrestrial vertebrates, the parathyroid glands are critical regulators of calcium homeostasis and the sole source of parathyroid hormone (PTH). Hyperparathyroidism and hypoparathyroidism are clinically important disorders affecting m
Externí odkaz:
https://doaj.org/article/fdbabb7074f14e289e86632096973964
Autor:
Cristina R Ferrone, Soldano Ferrone, Giulia Cattaneo, Marco Ventin, Venkata Rao Vantaku, Shahrzad Arya, Jingyu Jia, Luke Maggs, Xinhui Wang, Sareh Parangi
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/f36dfedf0515435481416bc7da09acc0
Autor:
Zhen Xu, Hyo Shik Shin, Yoo Hyung Kim, Seong Yun Ha, Jae-Kyung Won, Su-jin Kim, Young Joo Park, Sareh Parangi, Sun Wook Cho, Kyu Eun Lee
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionSecuring a well-established mouse model is important in identifying and validating new therapeutic targets for immuno-oncology. The C57BL/6 mouse is one of the most fully characterised immune system of any animal and provides powerful pla
Externí odkaz:
https://doaj.org/article/f97a6df409fa45cbb155c8080e778ba8
Autor:
Sasha K. Shillcutt, Sareh Parangi, Sarah Diekman, Reem Ghalib, Robin Schoenthaler, Linda M. Girgis, Ranna Parekh, Hansa Bhargava, Julie K. Silver
Publikováno v:
Health Equity, Vol 3, Iss 1, Pp 162-168 (2019)
Purpose: Women physicians do not advance in academic promotion or leadership at the same rate as their male counterparts. One factor contributing to academic promotion and advancement is the experience of serving in elected leadership positions. Alth
Externí odkaz:
https://doaj.org/article/567cd51b59e74b379cd0368ef13be41f
Autor:
Jeremy M. Quintana, David Arboleda, Huiyu Hu, Ella Scott, Gaurav Luthria, Sara Pai, Sareh Parangi, Ralph Weissleder, Miles A. Miller
Publikováno v:
Bioconjugate Chemistry. 33:1474-1484
Conjugation of therapeutic payloads to biologics including antibodies and albumin can enhance the selectively of drug delivery to solid tumors. However, achieving activity in tumors while avoiding healthy tissues remains a challenge, and payload acti
Autor:
David A. Barbie, Cloud Peter Paweletz, David Dornan, Kwok-Kin Wong, Genevieve M. Boland, Roger D. Kamm, Keith T. Flaherty, F. Stephen Hodi, Patrick A. Ott, Jochen H. Lorch, Paul T. Kirschmeier, Gordon J. Freeman, Eliezer M. Van Allen, Levi A. Garraway, Meenhard Herlyn, Juan Miret, Charles H. Yoon, Raphael Bueno, William G. Richards, Joshua Wong, Vivek Sivathanu, Thanh U. Barbie, Benchun Miao, Rohit Thummalapalli, Shunsuke Kitajima, Brian C. Miller, James M. Cleary, Sareh Parangi, Viswanath Gunda, Guilherme Rabinowits, Nicole R. LeBoeuf, Manisha Thakuria, Benjamin Izar, Parin Shah, Mei-Ju Su, Lisa Cameron, Anat O. Stemmer-Rachamimov, Jean-Pierre Eliane, Adriano Piris, Mai P. Hoang, Wei Huang, Glenn J. Hanna, Shuai Li, Hua Zhang, Eric S. Wang, Raven Vlahos, Marc R. Hammond, Tran C. Thai, Israel Cañadas, Michal Barzily-Rokni, Zhiheng Jia, Lance Stapleton, Maria Anguiano, Lauren Keogh, Robert E. Jones, Asaf Rotem, Alicia Smart, Bart Phillips, Prafulla C. Gokhale, Andrew Portell, Joshua A. Kaplan, Chandrasekar Venkataramani, Max Quinn, Ashley Merlino, Jong Wook Kim, Hans Vitzthum, Mark Bittinger, Sangeetha Palakurthi, Zhi Wei, Chaoran Cheng, Tian Tian, Gao Zhang, William Walker, Meng Xiao He, Diana Miao, Hongye Liu, Jiehui Deng, Michaela Bowden, Chensheng W. Zhou, Susanna Stinson, Elena Ivanova, Patrick H. Lizotte, Amir R. Aref, Russell W. Jenkins
PDOTS Movie 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b5816e3f89be3fcf42e03c4886a26bb
https://doi.org/10.1158/2159-8290.22531837.v1
https://doi.org/10.1158/2159-8290.22531837.v1
Autor:
David A. Barbie, Cloud Peter Paweletz, David Dornan, Kwok-Kin Wong, Genevieve M. Boland, Roger D. Kamm, Keith T. Flaherty, F. Stephen Hodi, Patrick A. Ott, Jochen H. Lorch, Paul T. Kirschmeier, Gordon J. Freeman, Eliezer M. Van Allen, Levi A. Garraway, Meenhard Herlyn, Juan Miret, Charles H. Yoon, Raphael Bueno, William G. Richards, Joshua Wong, Vivek Sivathanu, Thanh U. Barbie, Benchun Miao, Rohit Thummalapalli, Shunsuke Kitajima, Brian C. Miller, James M. Cleary, Sareh Parangi, Viswanath Gunda, Guilherme Rabinowits, Nicole R. LeBoeuf, Manisha Thakuria, Benjamin Izar, Parin Shah, Mei-Ju Su, Lisa Cameron, Anat O. Stemmer-Rachamimov, Jean-Pierre Eliane, Adriano Piris, Mai P. Hoang, Wei Huang, Glenn J. Hanna, Shuai Li, Hua Zhang, Eric S. Wang, Raven Vlahos, Marc R. Hammond, Tran C. Thai, Israel Cañadas, Michal Barzily-Rokni, Zhiheng Jia, Lance Stapleton, Maria Anguiano, Lauren Keogh, Robert E. Jones, Asaf Rotem, Alicia Smart, Bart Phillips, Prafulla C. Gokhale, Andrew Portell, Joshua A. Kaplan, Chandrasekar Venkataramani, Max Quinn, Ashley Merlino, Jong Wook Kim, Hans Vitzthum, Mark Bittinger, Sangeetha Palakurthi, Zhi Wei, Chaoran Cheng, Tian Tian, Gao Zhang, William Walker, Meng Xiao He, Diana Miao, Hongye Liu, Jiehui Deng, Michaela Bowden, Chensheng W. Zhou, Susanna Stinson, Elena Ivanova, Patrick H. Lizotte, Amir R. Aref, Russell W. Jenkins
In vitro kinase inhibitory activity of Compound 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aee36e2ca091d61ba8d57a8c6457e16a
https://doi.org/10.1158/2159-8290.22531825
https://doi.org/10.1158/2159-8290.22531825
Supplementary Data from CDK4/6 Inhibition Augments Antitumor Immunity by Enhancing T-cell Activation
Autor:
Kwok-Kin Wong, Nathanael S. Gray, David A. Barbie, Geoffrey I. Shapiro, Haribabu Arthanari, Norman E. Sharpless, W. Nicholas Haining, Jerome Ritz, Gordon J. Freeman, Sangeetha Palakurthi, Raphael Bueno, Genevieve M. Boland, Viswanath Gunda, Sareh Parangi, Jochen H. Lorch, William G. Richards, Jay C. Strum, Patrick J. Roberts, Eric Haines, Amanda J. Rode, Megan E. Cavanaugh, Ting Chen, Peng Gao, Hua Zhang, Yanxi Zhang, Annan Yang, Lauren E. Bufe, Max M. Quinn, Ashley A. Merlino, Patrick H. Lizotte, John E. Bisi, Jessica A. Sorrentino, Grit S. Herter-Sprie, Chensheng W. Zhou, Michaela Bowden, Cloud P. Paweletz, Elena Ivanova, Amir R. Aref, Hongye Liu, Wei Huang, Sandeep Chhabra, Kathleen Yates, Ruben Dries, Shuai Li, Russell W. Jenkins, Eric S. Wang, Jiehui Deng
Figure S1. Characterization of cells and CDK4/6 inhibitors; Figure S2. CDK6 phosphorylates serine residues of the regulatory domain of NFAT4 (NFATc3); Figure S3. Analysis of lung tumor immune infiltrates after CDK4/6 inhibition from KrasG12D (Kras),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22a01c7e72b06ed917fff29065c873f6
https://doi.org/10.1158/2159-8290.22531849.v1
https://doi.org/10.1158/2159-8290.22531849.v1
Autor:
David A. Barbie, Cloud Peter Paweletz, David Dornan, Kwok-Kin Wong, Genevieve M. Boland, Roger D. Kamm, Keith T. Flaherty, F. Stephen Hodi, Patrick A. Ott, Jochen H. Lorch, Paul T. Kirschmeier, Gordon J. Freeman, Eliezer M. Van Allen, Levi A. Garraway, Meenhard Herlyn, Juan Miret, Charles H. Yoon, Raphael Bueno, William G. Richards, Joshua Wong, Vivek Sivathanu, Thanh U. Barbie, Benchun Miao, Rohit Thummalapalli, Shunsuke Kitajima, Brian C. Miller, James M. Cleary, Sareh Parangi, Viswanath Gunda, Guilherme Rabinowits, Nicole R. LeBoeuf, Manisha Thakuria, Benjamin Izar, Parin Shah, Mei-Ju Su, Lisa Cameron, Anat O. Stemmer-Rachamimov, Jean-Pierre Eliane, Adriano Piris, Mai P. Hoang, Wei Huang, Glenn J. Hanna, Shuai Li, Hua Zhang, Eric S. Wang, Raven Vlahos, Marc R. Hammond, Tran C. Thai, Israel Cañadas, Michal Barzily-Rokni, Zhiheng Jia, Lance Stapleton, Maria Anguiano, Lauren Keogh, Robert E. Jones, Asaf Rotem, Alicia Smart, Bart Phillips, Prafulla C. Gokhale, Andrew Portell, Joshua A. Kaplan, Chandrasekar Venkataramani, Max Quinn, Ashley Merlino, Jong Wook Kim, Hans Vitzthum, Mark Bittinger, Sangeetha Palakurthi, Zhi Wei, Chaoran Cheng, Tian Tian, Gao Zhang, William Walker, Meng Xiao He, Diana Miao, Hongye Liu, Jiehui Deng, Michaela Bowden, Chensheng W. Zhou, Susanna Stinson, Elena Ivanova, Patrick H. Lizotte, Amir R. Aref, Russell W. Jenkins
Device loading, media addition, media extraction
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b6831b80aa77558ce1859b1d37bb61e
https://doi.org/10.1158/2159-8290.22531834.v1
https://doi.org/10.1158/2159-8290.22531834.v1