Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Sareetha, Kailayangiri"'
Autor:
Silke Jamitzky, Bianca Altvater, Carolin Krekeler, Laura Hoen, Caroline Brandes, Julia Ebbinghaus, Lisa Richter, Lisa Kosel, Laurin Ochs, Nicole Farwick, Katja Urban, Lena Kluge, Lara Bücker, Dennis Görlich, Ian C. D. Johnston, Rita Pfeifer, Wolfgang Hartmann, Claudia Rossig, Sareetha Kailayangiri
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Carbohydrate markers of immature cells during prenatal human development can be aberrantly expressed in cancers and deserve evaluation as immune targets. A candidate target in Ewing sarcoma is the globo-series ganglioside stage-specific embr
Externí odkaz:
https://doaj.org/article/c7a03da52b4a4a629ef2068b60b10500
Autor:
Sareetha Kailayangiri, Bianca Altvater, Nicole Farwick, Jutta Meltzer, Wolfgang Hartmann, Claudia Rossig
Publikováno v:
STAR Protocols, Vol 5, Iss 3, Pp 103199- (2024)
Summary: The detection of disialoganglioside GD2 on tumor biopsies, especially in paraffin-embedded tissues, has been challenging due to the glycolipid structure of GD2 and its membrane anchorage. Here, we present an immunofluorescence protocol for t
Externí odkaz:
https://doaj.org/article/6e27c866a2b14a24a2b2706fc20cf9d4
Autor:
Nicole Bäumer, Annika Scheller, Lisa Wittmann, Andreas Faust, Mara Apel, Subbaiah Chary Nimmagadda, Christiane Geyer, Katharina Grunert, Neele Kellmann, Matthias Peipp, Sareetha Kailayangiri, Matias Ezequiel Gutierrez Suburu, Cristian A. Strassert, Mathias Schenk, Lilo Greune, Christian Rüter, Petra Dersch, Wolfgang Hartmann, Claudia Rossig, Dario Neri, Carsten Müller-Tidow, Christian Schwöppe, Christoph Schliemann, Cyrus Khandanpour, Georg Lenz, Wolfgang E. Berdel, Sebastian Bäumer
Publikováno v:
Journal of Hematology & Oncology, Vol 15, Iss 1, Pp 1-26 (2022)
Abstract Background Acute myeloid leukemia (AML) is a fatal clonal hematopoietic malignancy, which results from the accumulation of several genetic aberrations in myeloid progenitor cells, with a worldwide 5-year survival prognosis of about 30%. Ther
Externí odkaz:
https://doaj.org/article/522914dd6cf246468f2f5d959f5f9ca1
Autor:
Malena Wiebel, Sareetha Kailayangiri, Bianca Altvater, Jutta Meltzer, Kay Grobe, Sabine Kupich, Claudia Rossig
Publikováno v:
Cancer Reports, Vol 4, Iss 5, Pp n/a-n/a (2021)
Abstract Background Chimeric antigen receptor (CAR) T‐cell therapy of pediatric sarcomas is challenged by the paucity of targetable cell surface antigens. A candidate target in osteosarcoma (OS) is the ganglioside GD2, but heterogeneous expression
Externí odkaz:
https://doaj.org/article/782e6053cd61477eb41e9f9928394a21
Autor:
Magdalene Cyra, Miriam Schulte, Ruth Berthold, Lorena Heinst, Esther-Pia Jansen, Inga Grünewald, Sandra Elges, Olle Larsson, Christoph Schliemann, Konrad Steinestel, Susanne Hafner, Thomas Simmet, Eva Wardelmann, Sareetha Kailayangiri, Claudia Rossig, Ilka Isfort, Marcel Trautmann, Wolfgang Hartmann
Publikováno v:
Cellular Oncology. 45:399-413
Purpose Synovial sarcoma (SySa) is a rare soft tissue tumor characterized by a reciprocal t(X;18) translocation. The chimeric SS18-SSX fusion protein represents the major driver of the disease, acting as aberrant transcriptional dysregulator. Oncogen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::039aa297dd1859faa5b57d9b009a972f
https://doi.org/10.1007/s13402-022-00673-w
https://doi.org/10.1007/s13402-022-00673-w
Autor:
Claudia Rossig, Martin Pule, Heribert Juergens, Dario Campana, Sareetha Kailayangiri, Katharina Schweer, Jaane Temme, Sibylle Pscherer, Silke Landmeier, Bianca Altvater
CCR Translation for the Article from 2B4 (CD244) Signaling by Recombinant Antigen-specific Chimeric Receptors Costimulates Natural Killer Cell Activation to Leukemia and Neuroblastoma Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d83124e7a6c5fef56d9a13eee7173e4
https://doi.org/10.1158/1078-0432.22441602.v1
https://doi.org/10.1158/1078-0432.22441602.v1
Autor:
Claudia Rossig, Martin Pule, Heribert Juergens, Dario Campana, Sareetha Kailayangiri, Katharina Schweer, Jaane Temme, Sibylle Pscherer, Silke Landmeier, Bianca Altvater
Purpose: Novel natural killer (NK) cell–directed strategies in cancer immunotherapy aim at specifically modulating the balance between NK cell receptor signals toward tumor-specific activation. The signaling lymphocyte activation molecule–related
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1debefa13fc813419e20aff5ab27e1e4
https://doi.org/10.1158/1078-0432.c.6518604
https://doi.org/10.1158/1078-0432.c.6518604
Autor:
Wolfgang Hartmann, Marcel Trautmann, Eva Wardelmann, Olle Larsson, Patrick Schöffski, Agnieszka Wozniak, Thomas Simmet, Susanne Hafner, Jan-Henrik Mikesch, Eva Eßeling, Sebastian Huss, Inga Grünewald, Konrad Steinestel, Claudia Rossig, Bianca Altvater, Sareetha Kailayangiri, Sandra Elges, Magdalene Cyra, Ilka Isfort
Treatments with mono verteporfin and the combination of verteporfin and doxorubicin resulted in a reduction of YAP, TAZ, FOXM1, CTGF and PLK1 protein levels compared to the vehicle control and mono doxorubicin treatment in total protein extracts of a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::666294a30a468e79a1567aba2cce3b68
https://doi.org/10.1158/1078-0432.22470903
https://doi.org/10.1158/1078-0432.22470903
Autor:
Wolfgang Hartmann, Marcel Trautmann, Eva Wardelmann, Olle Larsson, Patrick Schöffski, Agnieszka Wozniak, Thomas Simmet, Susanne Hafner, Jan-Henrik Mikesch, Eva Eßeling, Sebastian Huss, Inga Grünewald, Konrad Steinestel, Claudia Rossig, Bianca Altvater, Sareetha Kailayangiri, Sandra Elges, Magdalene Cyra, Ilka Isfort
Purpose:Synovial sarcoma is a soft tissue malignancy characterized by a reciprocal t(X;18) translocation. The chimeric SS18-SSX fusion protein acts as a transcriptional dysregulator representing the major driver of the disease; however, the signaling
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e4c4b88d52f85bd1b228b281a795543
https://doi.org/10.1158/1078-0432.c.6527724
https://doi.org/10.1158/1078-0432.c.6527724
Autor:
Wolfgang Hartmann, Marcel Trautmann, Eva Wardelmann, Olle Larsson, Patrick Schöffski, Agnieszka Wozniak, Thomas Simmet, Susanne Hafner, Jan-Henrik Mikesch, Eva Eßeling, Sebastian Huss, Inga Grünewald, Konrad Steinestel, Claudia Rossig, Bianca Altvater, Sareetha Kailayangiri, Sandra Elges, Magdalene Cyra, Ilka Isfort
Supplementary Table S1: Clinicopathological characteristics of synovial sarcoma tissue specimens (n=65) and semi-quantitative immunohistochemistry results Supplementary Table S2: Primer sequences
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::502b187ad709ce01d0e291d26b390006
https://doi.org/10.1158/1078-0432.22470900
https://doi.org/10.1158/1078-0432.22470900