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pro vyhledávání: '"Sardar Shamshair Singh"'
Autor:
Shili Xu, Lakshmi Narasu, Nouri Neamati, Raveendra Dayam, Jagarlapudi A. R. P. Sarma, Sardar Shamshair Singh
Publikováno v:
Current Topics in Medicinal Chemistry. 14:2020-2030
A tremendous research on Poly (ADP-ribose) polymerase (PARP) pertaining to cancer and ischemia is in very rapid progress. PARP's are a specific class of enzymes that repairs the damaged DNA. Recent findings suggest also that PARP-1 is the most abunda
Autor:
Jyoti Roy, Rohith Kotla, B.V.S. Suneel Kumar, Rambabu Gundla, Muttineni Ravikumar, Jagarlapudi A. R. P. Sarma, Revanth Buddiga, Sardar Shamshair Singh
Publikováno v:
Journal of Molecular Modeling. 17:151-163
Structure and ligand based pharmacophore modeling and docking studies carried out using diversified set of c-Jun N-terminal kinase-3 (JNK3) inhibitors are presented in this paper. Ligand based pharmacophore model (LBPM) was developed for 106 inhibito