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Admixture mapping of severe asthma exacerbations in Hispanic/Latino children and youth.

Autor: Herrera-Luis E; Genomics and Health Group, Department of Biochemistry, Microbiology, Cell Biology, and Genetics, Universidad de La Laguna (ULL), La Laguna, Spain., Mak ACY; Department of Medicine, University of California San Francisco, San Francisco, California, USA., Perez-Garcia J; Genomics and Health Group, Department of Biochemistry, Microbiology, Cell Biology, and Genetics, Universidad de La Laguna (ULL), La Laguna, Spain., Martin-Gonzalez E; Genomics and Health Group, Department of Biochemistry, Microbiology, Cell Biology, and Genetics, Universidad de La Laguna (ULL), La Laguna, Spain., Eng C; Department of Medicine, University of California San Francisco, San Francisco, California, USA., Beckman KB; University of Minnesota Genomics Center, Minneapolis, Minnesota, USA., Huntsman S; Department of Medicine, University of California San Francisco, San Francisco, California, USA., Hu D; Department of Medicine, University of California San Francisco, San Francisco, California, USA., González-Pérez R; Allergy Department, Hospital Universitario de Canarias, La Laguna, Spain.; Severe Asthma Unit, Allergy Department, Hospital Universitario de Canarias, La Laguna, Spain., Hernández-Pérez JM; Pulmonary Medicine, Hospital Universitario N.S. de Candelaria, Santa Cruz de Tenerife, Spain.; Pulmonary Medicine, Hospital Universitario de La Palma, Breña alta, Spain., Mederos-Luis E; Allergy Department, Hospital Universitario de Canarias, La Laguna, Spain., Sio YY; Department of Biological Sciences, National University of Singapore, Singapore., Poza-Guedes P; Allergy Department, Hospital Universitario de Canarias, La Laguna, Spain.; Severe Asthma Unit, Allergy Department, Hospital Universitario de Canarias, La Laguna, Spain., Sardón O; Division of Pediatric Respiratory Medicine, Hospital Universitario Donostia, San Sebastián, Spain.; Department of Pediatrics, University of the Basque Country (UPV/EHU), San Sebastián, Spain., Corcuera P; Division of Pediatric Respiratory Medicine, Hospital Universitario Donostia, San Sebastián, Spain., Sánchez-Machín I; Allergy Department, Hospital Universitario de Canarias, La Laguna, Spain., Korta-Murua J; Division of Pediatric Respiratory Medicine, Hospital Universitario Donostia, San Sebastián, Spain.; Department of Pediatrics, University of the Basque Country (UPV/EHU), San Sebastián, Spain., Martínez-Rivera C; Servicio de Neumología, Hospital Universitario Germans Trias i Pujol, Universitat Autònoma de Barcelona, Badalona, Spain.; CIBER de Enfermedades Respiratorias, Instituto de Salud Carlos III, Madrid, Spain., Mullol J; CIBER de Enfermedades Respiratorias, Instituto de Salud Carlos III, Madrid, Spain.; Rhinology Unit & Smell Clinic, ENT Department; Clinical & Experimental Respiratory Immunoallergy (IDIBAPS), Universitat de Barcelona, Barcelona, Spain., Muñoz X; CIBER de Enfermedades Respiratorias, Instituto de Salud Carlos III, Madrid, Spain.; Servicio de Neumología, Hospital Vall d'Hebron, Barcelona, Spain., Valero A; CIBER de Enfermedades Respiratorias, Instituto de Salud Carlos III, Madrid, Spain.; Allergy Unit & Severe Asthma Unit, Pneumonology and Allergy Department, Hospital Clínic, IDIBAPS, Universitat de Barcelona, Barcelona, Spain., Sastre J; CIBER de Enfermedades Respiratorias, Instituto de Salud Carlos III, Madrid, Spain.; Allergy Department, Hospital Universitario Fundación Jiménez Díaz, Madrid, Spain., Garcia-Aymerich J; Spanish Consortium for Research on Epidemiology and Public Health (CIBERESP), Madrid, Spain.; ISGlobal, Barcelona, Spain.; Universitat Pompeu Fabra, Barcelona, Spain., Llop S; Spanish Consortium for Research on Epidemiology and Public Health (CIBERESP), Madrid, Spain.; Epidemiology and Environmental Health Joint Research Unit, FISABIO, Universitat Jaume I, Universitat de Valencia, Valencia, Spain., Torrent M; Ib-salut, Area de Salut de Menorca, Menorca, Spain., Casas M; ISGlobal, Barcelona, Spain.; Universitat Pompeu Fabra, Barcelona, Spain., Rodríguez-Santana JR; Centro de Neumología Pediátrica, San Juan, Puerto Rico., Villar J; CIBER de Enfermedades Respiratorias, Instituto de Salud Carlos III, Madrid, Spain.; Multidisciplinary Organ Dysfunction Evaluation Research Network (MODERN), Research Unit, Hospital Universitario Dr. Negrín, Las Palmas de Gran Canaria, Spain., Del Pozo V; CIBER de Enfermedades Respiratorias, Instituto de Salud Carlos III, Madrid, Spain.; Immunology Department, Instituto de Investigación Sanitaria Hospital Universitario Fundación Jiménez Díaz, Madrid, Spain., Lorenzo-Diaz F; Genomics and Health Group, Department of Biochemistry, Microbiology, Cell Biology, and Genetics, Universidad de La Laguna (ULL), La Laguna, Spain.; Instituto Universitario de Enfermedades Tropicales y Salud Pública de Canarias (IUETSPC), Universidad de La Laguna (ULL), La Laguna, Spain., Williams LK; Center for Individualized and Genomic Medicine Research, Department of Internal Medicine, Henry Ford Health System, Detroit, Michigan, USA., Melén E; Department of Clinical Sciences and Education, Södersjukhuset, Karolinska Institutet, Stockholm, Sweden.; Sachs' Children's Hospital, South General Hospital, Stockholm, Sweden., Chew FT; Department of Biological Sciences, National University of Singapore, Singapore., Borrell LN; Department of Epidemiology & Biostatistics, Graduate School of Public Health & Health Policy, City University of New York, New York, New York, USA., Burchard EG; Department of Medicine, University of California San Francisco, San Francisco, California, USA.; Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, California, USA., Pino-Yanes M; Genomics and Health Group, Department of Biochemistry, Microbiology, Cell Biology, and Genetics, Universidad de La Laguna (ULL), La Laguna, Spain mdelpino@ull.edu.es.; CIBER de Enfermedades Respiratorias, Instituto de Salud Carlos III, Madrid, Spain.; Instituto de Tecnologías Biomédicas (ITB), Universidad de La Laguna (ULL), La Laguna, Spain.

Publikováno v: Thorax [Thorax] 2023 Mar; Vol. 78 (3), pp. 233-241. Date of Electronic Publication: 2022 Sep 30.

Multi-ancestry genome-wide association study of asthma exacerbations.

Autor: Herrera-Luis E; Genomics and Health Group, Department of Biochemistry, Microbiology, Cell Biology and Genetics, Universidad de La Laguna (ULL), San Cristóbal de La Laguna, Tenerife, Spain., Ortega VE; Division of Respiratory Medicine, Department of Internal Medicine, Mayo Clinic, Scottsdale, Arizona, USA., Ampleford EJ; Department of Internal Medicine, Center for Precision Medicine, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA., Sio YY; Department of Biological Sciences, National University of Singapore, Singapore City, Singapore., Granell R; MRC Integrative Epidemiology Unit (IEU), Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK., de Roos E; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands.; Department of Respiratory Medicine, Ghent University Hospital, Ghent, Belgium., Terzikhan N; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands.; Department of Respiratory Medicine, Ghent University Hospital, Ghent, Belgium., Vergara EE; Institute of Computation Biology, Helmholtz Zentrum München, German Research Center for Environmental Health, Munich, Germany., Hernandez-Pacheco N; Department of Clinical Sciences and Education, Södersjukhuset, Karolinska Institutet, Stockholm, Sweden.; CIBER de Enfermedades Respiratorias (CIBERES), Madrid, Spain., Perez-Garcia J; Genomics and Health Group, Department of Biochemistry, Microbiology, Cell Biology and Genetics, Universidad de La Laguna (ULL), San Cristóbal de La Laguna, Tenerife, Spain., Martin-Gonzalez E; Genomics and Health Group, Department of Biochemistry, Microbiology, Cell Biology and Genetics, Universidad de La Laguna (ULL), San Cristóbal de La Laguna, Tenerife, Spain., Lorenzo-Diaz F; Genomics and Health Group, Department of Biochemistry, Microbiology, Cell Biology and Genetics, Universidad de La Laguna (ULL), San Cristóbal de La Laguna, Tenerife, Spain.; Instituto Universitario de Enfermedades Tropicales y Salud Pública de Canarias (IUETSPC), Universidad de La Laguna (ULL), San Cristóbal de La Laguna, Tenerife, Spain., Hashimoto S; Department of Respiratory Medicine, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, The Netherlands., Brinkman P; Department of Respiratory Medicine, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, The Netherlands., Jorgensen AL; Department of Health Data Science, Institute of Population Health, University of Liverpool, Liverpool, UK., Yan Q; Department of Obstetrics and Gynecology, Columbia University Irving Medical Center, New York, New York, USA., Forno E; Division of Pediatric Pulmonary Medicine, UPMC Children's Hospital of Pittsburgh, University of Pittsburgh, Pittsburgh, Pennsylvania, USA., Vijverberg SJ; Department of Respiratory Medicine, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.; Division of Pharmacoepidemiology and Clinical Pharmacology, Faculty of Science, Utrecht University, Utrecht, The Netherlands.; Department of Paediatric Respiratory Medicine and Allergy, Emma's Children Hospital, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands., Lethem R; MRC Integrative Epidemiology Unit (IEU), Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK., Espuela-Ortiz A; Genomics and Health Group, Department of Biochemistry, Microbiology, Cell Biology and Genetics, Universidad de La Laguna (ULL), San Cristóbal de La Laguna, Tenerife, Spain., Gorenjak M; Center for Human Molecular Genetics and Pharmacogenomics, Faculty of Medicine, University of Maribor, Maribor, Slovenia., Eng C; Department of Medicine, University of California San Francisco, San Francisco, California, USA., González-Pérez R; Allergy Department, Hospital Universitario de Canarias, Santa Cruz de Tenerife, Tenerife, Spain.; Severe Asthma Unit, Allergy Department, Hospital Universitario de Canarias, Santa Cruz de Tenerife, Tenerife, Spain., Hernández-Pérez JM; Pulmonary Medicine, Hospital Universitario de N.S de Candelaria, Santa Cruz de Tenerife, Spain.; Pulmonary Medicine, Hospital General de La Palma, La Palma, Santa Cruz de Tenerife, Spain., Poza-Guedes P; Allergy Department, Hospital Universitario de Canarias, Santa Cruz de Tenerife, Tenerife, Spain.; Severe Asthma Unit, Allergy Department, Hospital Universitario de Canarias, Santa Cruz de Tenerife, Tenerife, Spain., Sardón O; Division of Pediatric Respiratory Medicine, Hospital Universitario Donostia, San Sebastián, Spain.; Department of Pediatrics, University of the Basque Country (UPV/EHU), San Sebastián, Spain., Corcuera P; Division of Pediatric Respiratory Medicine, Hospital Universitario Donostia, San Sebastián, Spain., Hawkins GA; Department of Biochemistry, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA., Marsico A; Computational Health Center, Helmholtz Zentrum München, German Research Center for Environmental Health, Munich, Germany., Bahmer T; LungenClinic Grosshansdorf, Pneumology, Grosshansdorf, Germany.; Airway Research Center North (ARCN), Members of the Germany Center for Lung Research (DZL), Grosshansdorf, Germany., Rabe KF; LungenClinic Grosshansdorf, Pneumology, Grosshansdorf, Germany.; Airway Research Center North (ARCN), Members of the Germany Center for Lung Research (DZL), Grosshansdorf, Germany., Hansen G; Department of Pediatric Pneumology, Allergology and Neonatology, Hannover Medical School, Hannover, Germany., Kopp MV; Division of Pediatric Pneumology & Allergology, University Medical Center Schleswig-Holstein, Lübeck, Germany.; Airway Research Center North (ARCN), Members of the Germany Center for Lung Research (DZL), Lübeck, Germany.; Department of Paediatric Respiratory Medicine, Inselspital, University Children's Hospital of Bern, University of Bern, Bern, Switzerland., Rios R; Programa de Pós Graduação em Imunologia (PPGIm), Instituto de Ciências da Saúde, Universidade Federal da Bahia (UFBA), Salvador, Brazil., Cruz MJ; CIBER de Enfermedades Respiratorias (CIBERES), Madrid, Spain.; Servicio de Neumología, Hospital Vall d'Hebron, Barcelona, Spain., González-Barcala FJ; Servicio de Neumología, Complejo Hospitalario Universitario de Santiago, Santiago de Compostela, Spain., Olaguibel JM; CIBER de Enfermedades Respiratorias (CIBERES), Madrid, Spain.; Servicio de Alergología, Complejo Hospitalario de Navarra, Pamplona, Navarra, Spain., Plaza V; CIBER de Enfermedades Respiratorias (CIBERES), Madrid, Spain.; Departamento de Medicina Respiratoria, Hospital de la Santa Creu i Sant Pau, Instituto de Investigación Biomédica Sant Pau (IIB Sant Pau), Barcelona, Spain., Quirce S; CIBER de Enfermedades Respiratorias (CIBERES), Madrid, Spain.; Department of Allergy, La Paz University Hospital, IdiPAZ, Madrid, Spain., Canino G; Behavioral Sciences Research Institute, University of Puerto Rico, San Juan, Puerto Rico., Cloutier M; Department of Pediatrics, University of Connecticut, Farmington, Connecticut, USA., Del Pozo V; CIBER de Enfermedades Respiratorias (CIBERES), Madrid, Spain.; Immunology Department, Instituto de Investigación Sanitaria Hospital Universitario Fundación Jiménez Díaz, Madrid, Spain., Rodriguez-Santana JR; Centro de Neumología Pediátrica, San Juan, Puerto Rico., Korta-Murua J; Department of Pediatrics, University of the Basque Country (UPV/EHU), San Sebastián, Spain., Villar J; CIBER de Enfermedades Respiratorias (CIBERES), Madrid, Spain.; Multidisciplinary Organ Dysfunction Evaluation Research Network, Research Unit, Hospital Universitario Dr. Negrín, Las Palmas de Gran Canaria, Spain., Potočnik U; Laboratory for Biochemistry, Molecular Biology and Genomics, Faculty for Chemistry and Chemical Engineering, University of Maribor, Maribor, Slovenia., Figueiredo C; Instituto de Ciências da Saúde, Universidade Federal da Bahia, Salvador, Brazil., Kabesch M; Department of Paediatric Pneumology and Allergy, University Children's Hospital Regensburg (KUNO), Regensburg, Germany., Mukhopadhyay S; Academic Department of Paediatrics, Brighton and Sussex Medical School, Royal Alexandra Children's Hospital, Brighton, UK.; Population Pharmacogenetics Group, Biomedical Research Institute, Ninewells Hospital and Medical School, University of Dundee, Dundee, UK., Pirmohamed M; Department of Pharmacology and Therapeutics, Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool, UK., Hawcutt DB; Department of Women's and Children's Health, University of Liverpool, Liverpool, UK.; Alder Hey Children's Hospital, Liverpool, UK.; NIHR Alder Hey Clinical Research Facility, Alder Hey Children's Hospital, Liverpool, UK., Melén E; Department of Clinical Sciences and Education, Södersjukhuset, Karolinska Institutet, Stockholm, Sweden.; Sachs' Children's Hospital, South General Hospital, Stockholm, Sweden., Palmer CN; Population Pharmacogenetics Group, Biomedical Research Institute, Ninewells Hospital and Medical School, University of Dundee, Dundee, UK., Turner S; Child Health, University of Aberdeen, Aberdeen, UK., Maitland-van der Zee AH; Department of Respiratory Medicine, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.; Division of Pharmacoepidemiology and Clinical Pharmacology, Faculty of Science, Utrecht University, Utrecht, The Netherlands.; Department of Paediatric Respiratory Medicine and Allergy, Emma's Children Hospital, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands., von Mutius E; Institute for Asthma and Allergy Prevention, Helmholtz Zentrum München, German Research Center for Environmental Health, Munich, Germany.; Dr von Hauner Children's Hospital, Ludwig-Maximilians-Universität, Munich, Germany.; Comprehensive Pneumology Center Munich (CPC-M), Member of the German Center for Lung Research, Munich, Germany., Celedón JC; Division of Pediatric Pulmonary Medicine, UPMC Children's Hospital of Pittsburgh, University of Pittsburgh, Pittsburgh, Pennsylvania, USA., Brusselle G; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands.; Department of Respiratory Medicine, Ghent University Hospital, Ghent, Belgium.; Department of Respiratory Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands., Chew FT; Department of Biological Sciences, National University of Singapore, Singapore City, Singapore., Bleecker E; Division of Genetics, Genomics, and Precision Medicine, Department of Internal Medicine, University of Arizona College of Medicine, Tucson, Arizona, USA., Meyers D; Division of Genetics, Genomics, and Precision Medicine, Department of Internal Medicine, University of Arizona College of Medicine, Tucson, Arizona, USA., Burchard EG; Severe Asthma Unit, Allergy Department, Hospital Universitario de Canarias, Santa Cruz de Tenerife, Tenerife, Spain.; Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, California, USA., Pino-Yanes M; Genomics and Health Group, Department of Biochemistry, Microbiology, Cell Biology and Genetics, Universidad de La Laguna (ULL), San Cristóbal de La Laguna, Tenerife, Spain.; CIBER de Enfermedades Respiratorias (CIBERES), Madrid, Spain.; Instituto de Tecnologías Biomédicas (ITB), Universidad de La Laguna (ULL), San Cristóbal de La Laguna, Tenerife, Spain.

Publikováno v: Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology [Pediatr Allergy Immunol] 2022 Jun; Vol. 33 (6), pp. e13802.

Risk factors for bronchiolitis, recurrent wheezing, and related hospitalization in preterm infants during the first year of life

Autor: Pérez-Yarza EG, Moreno-Galdó A, Ramilo O, Rubí T, Escribano A, Torres A, Sardón O, Oliva C, Pérez G, Cortell I, Rovira-Amigo S, Pastor-Vivero MD, Pérez-Frías J, Velasco V, Torres-Borrego J, Figuerola J, Barrio MI, García-Hernández G, Mejías A, SAREPREM 3235 investigators

Publikováno v: PEDIATRIC ALLERGY AND IMMUNOLOGY
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
instname

BackgroundAirway diseases are highly prevalent in infants and cause significant morbidity. We aimed to determine the incidence and risk factors for respiratory morbidity in a Spanish cohort of moderate-to-late preterm (MLP) infants prospectively foll

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=RECOLECTA___::566f607710ee5d1792f73324d5a72cc0
https://fundanet.iislafe.san.gva.es/publicaciones/ProdCientif/PublicacionFrw.aspx?id=1182

Precision Medicine in Childhood Asthma: Omic Studies of Treatment Response.

Autor: Perez-Garcia J; Genomics and Health Group, Department of Biochemistry, Microbiology, Cell Biology and Genetics, Universidad de La Laguna, 38200 San Cristóbal de La Laguna, Spain., Herrera-Luis E; Genomics and Health Group, Department of Biochemistry, Microbiology, Cell Biology and Genetics, Universidad de La Laguna, 38200 San Cristóbal de La Laguna, Spain., Lorenzo-Diaz F; Genomics and Health Group, Department of Biochemistry, Microbiology, Cell Biology and Genetics, Universidad de La Laguna, 38200 San Cristóbal de La Laguna, Spain.; Instituto Universitario de Enfermedades Tropicales y Salud Pública de Canarias (IUETSPC), Universidad de La Laguna, 38200 San Cristóbal de La Laguna, Spain., González M; Instituto Universitario de Enfermedades Tropicales y Salud Pública de Canarias (IUETSPC), Universidad de La Laguna, 38200 San Cristóbal de La Laguna, Spain.; Department of Biochemistry, Microbiology, Cell Biology and Genetics, Universidad de La Laguna, 38200 San Cristóbal de La Laguna, Spain., Sardón O; Division of Pediatric Respiratory Medicine, Hospital Universitario Donostia, 20014 San Sebastián, Spain.; Department of Pediatrics, University of the Basque Country (UPV/EHU), 20014 San Sebastián, Spain., Villar J; Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERES), Instituto de Salud Carlos III, 28029 Madrid, Spain.; Multidisciplinary Organ Dysfunction Evaluation Research Network, Research Unit, Hospital Universitario Dr Negrín, 35019 Las Palmas de Gran Canaria, Spain.; Keenan Research Center for Biomedical Science at the Li Ka Shing Knowledge Institute, St Michael's Hospital, Toronto, ON M5B 1W8, Canada., Pino-Yanes M; Genomics and Health Group, Department of Biochemistry, Microbiology, Cell Biology and Genetics, Universidad de La Laguna, 38200 San Cristóbal de La Laguna, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERES), Instituto de Salud Carlos III, 28029 Madrid, Spain.; Instituto de Tecnologías Biomédicas (ITB), Universidad de La Laguna, 38200 San Cristóbal de La Laguna, Spain.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2020 Apr 21; Vol. 21 (8). Date of Electronic Publication: 2020 Apr 21.