Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Sarcoplasmic Reticulum Calcium-Transporting ATPases/metabolism"'
Autor:
Heather L. Petrick, Stuart Brownell, Bayley Vachon, Henver S. Brunetta, Rachel M. Handy, Luc J.C. van Loon, Coral L. Murrant, Graham P. Holloway
Publikováno v:
American Journal of Physiology : Endocrinology and Metabolism, 323(2), E171-E184. American Physiological Society
Rapid oscillations in cytosolic calcium (Ca2+) coordinate muscle contraction, relaxation, and physical movement. Intriguingly, dietary nitrate decreases ATP cost of contraction, increases force production, and increases cytosolic Ca2+, which would se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d04fad4ecffc16a433f22ec4850d7e7b
https://doi.org/10.1152/ajpendo.00371.2021
https://doi.org/10.1152/ajpendo.00371.2021
Autor:
Enrico Pierantozzi, Péter Szentesi, Cecilia Paolini, Beatrix Dienes, János Fodor, Tamás Oláh, Barbara Colombini, Dilson E. Rassier, Egidio Maria Rubino, Stephan Lange, Daniela Rossi, László Csernoch, Maria Angela Bagni, Carlo Reggiani, Vincenzo Sorrentino
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 3; Pages: 1319
International Journal of Molecular Sciences, Vol 23, Iss 1319, p 1319 (2022)
Pierantozzi, E, Szentesi, P, Paolini, C, Dienes, B, Fodor, J, Oláh, T, Colombini, B, Rassier, D E, Rubino, E M, Lange, S, Rossi, D, Csernoch, L, Bagni, M A, Reggiani, C & Sorrentino, V 2022, ' Impaired Intracellular Ca 2+ Dynamics, M-Band and Sarcomere Fragility in Skeletal Muscles of Obscurin KO Mice. ', International Journal of Molecular Sciences, vol. 23, no. 3 . https://doi.org/10.3390/ijms23031319
International Journal of Molecular Sciences, Vol 23, Iss 1319, p 1319 (2022)
Pierantozzi, E, Szentesi, P, Paolini, C, Dienes, B, Fodor, J, Oláh, T, Colombini, B, Rassier, D E, Rubino, E M, Lange, S, Rossi, D, Csernoch, L, Bagni, M A, Reggiani, C & Sorrentino, V 2022, ' Impaired Intracellular Ca 2+ Dynamics, M-Band and Sarcomere Fragility in Skeletal Muscles of Obscurin KO Mice. ', International Journal of Molecular Sciences, vol. 23, no. 3 . https://doi.org/10.3390/ijms23031319
Obscurin is a giant sarcomeric protein expressed in striated muscles known to establish several interactions with other proteins of the sarcomere, but also with proteins of the sarcoplasmic reticulum and costameres. Here, we report experiments aiming
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0d905a26454a3391f077ae8a033acf5
http://hdl.handle.net/11365/1182697
http://hdl.handle.net/11365/1182697
Autor:
Duan, Jingxian, Navarro-Dorado, Jorge, Clark, Jill H., Kinnear, Nicholas P., Meinke, Peter, Schirmer, Eric C., Evans, A. Mark
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Nature Communications
Duan, J, Navarro-Dorado, J, Clark, J H, Kinnear, N P, Meinke, P, Schirmer, E C & Evans, A M 2019, ' The cell-wide web coordinates cellular processes by directing site-specific Ca2+ flux across cytoplasmic nanocourses ', vol. 10, no. 1, 2299 . https://doi.org/10.1038/s41467-019-10055-w
Nature Communications
Duan, J, Navarro-Dorado, J, Clark, J H, Kinnear, N P, Meinke, P, Schirmer, E C & Evans, A M 2019, ' The cell-wide web coordinates cellular processes by directing site-specific Ca2+ flux across cytoplasmic nanocourses ', vol. 10, no. 1, 2299 . https://doi.org/10.1038/s41467-019-10055-w
Ca2+ coordinates diverse cellular processes, yet how function-specific signals arise is enigmatic. We describe a cell-wide network of distinct cytoplasmic nanocourses with the nucleus at its centre, demarcated by sarcoplasmic reticulum (SR) junctions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::ffc11d47fb4f5fa382f7478ce0c96696
https://doaj.org/article/1588c52787ed490bbdbdcbdbcc560603
https://doaj.org/article/1588c52787ed490bbdbdcbdbcc560603
Publikováno v:
Cell Calcium, 72, 132-134. ELSEVIER SCI LTD
Loss of SERCA function contributes to reduced contractility, Ca2+ overload and arrhythmias in the diseased heart. A long non-coding RNA (ZFAS1) upregulated in cardiac disease is reported to directly inhibit SERCA function. The implications for cardia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1622f52ef864792204d5feee860b360
https://doi.org/10.1016/j.ceca.2018.05.005
https://doi.org/10.1016/j.ceca.2018.05.005
Autor:
S. Lazar, Karen Søgaard, Jenny Hadrévi, Niels Ørtenblad, Gisela Sjøgaard, Mary F. Barbe, Ulrik Frandsen, Eleanor Boyle
Publikováno v:
BioMed Research International, Vol 2019 (2019)
Hadrevi, J, Barbe, M F, Ørtenblad, N, Frandsen, U, Boyle, E, Lazar, S, Sjøgaard, G & Søgaard, K 2019, ' Calcium Fluxes in Work-Related Muscle Disorder : Implications from a Rat Model ', BioMed Research International, vol. 2019, 5040818 . https://doi.org/10.1155/2019/5040818, https://doi.org/10.1155/2019/5040818
BioMed Research International
Hadrevi, J, Barbe, M F, Ørtenblad, N, Frandsen, U, Boyle, E, Lazar, S, Sjøgaard, G & Søgaard, K 2019, ' Calcium Fluxes in Work-Related Muscle Disorder : Implications from a Rat Model ', BioMed Research International, vol. 2019, 5040818 . https://doi.org/10.1155/2019/5040818, https://doi.org/10.1155/2019/5040818
BioMed Research International
Introduction. Ca2+ regulatory excitation-contraction coupling properties are key topics of interest in the development of work-related muscle myalgia and may constitute an underlying cause of muscle pain and loss of force generating capacity. Method.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32943e3265bf5dc03e4ea05863f2fdb0
Autor:
Sabine Steffens, Mohamed Asrih
Publikováno v:
Cardiovascular Pathology, Vol. 22, No 2 (2013) pp. 117-125
The prevalence of heart failure independent of coronary artery disease and hypertension is increasing rapidly in diabetic patients. Thus, this pathophysiology has been recognized as a distinct clinical entity termed "diabetic cardiomyopathy." Several
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1472409c05c561a0a1d4fcee5b502f5b
https://doi.org/10.1016/j.carpath.2012.07.004
https://doi.org/10.1016/j.carpath.2012.07.004
Publikováno v:
Seow, Y, Sibley, C R & Wood, M J A 2012, ' Artificial mirtron-mediated gene knockdown : Functional DMPK silencing in mammalian cells ', RNA, vol. 18, no. 7, pp. 1328-37 . https://doi.org/10.1261/rna.030601.111
Mirtrons are introns that form pre-miRNA hairpins after splicing to produce RNA interference (RNAi) effectors distinct from Drosha-dependent intronic miRNAs. Here we present a design algorithm for artificial mirtrons and demonstrate, for the first ti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2e260dd95281a9bd39228c0b01fffb9
http://ora.ox.ac.uk/objects/uuid:53b69888-2b05-415c-8a81-a18d42af49b0
http://ora.ox.ac.uk/objects/uuid:53b69888-2b05-415c-8a81-a18d42af49b0
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e31905 (2012)
PLoS ONE
PLoS ONE
Intracellular pH (pHi) and Ca(2+) regulate essentially all aspects of cellular activities. Their inter-relationship has not been mechanistically explored. In this study, we used bases and acetic acid to manipulate the pHi. We found that transient pHi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ac5fd64b3af7b0edea188113128218c
http://europepmc.org/articles/PMC3288054?pdf=render
http://europepmc.org/articles/PMC3288054?pdf=render
Autor:
Stephen S.M. Chung, Sookja K. Chung, Wing Tim Cheng, Gennadi M. Kravtsov, WH Tang, Xiu Yun Hou, Xiao Yong Tong
Hyperglycemia is an indication of poor outcome for heart attack patients, even for nondiabetic patients with stress-induced hyperglycemia. Previous studies showed that inhibition of aldose reductase, the first and rate-limiting enzyme of the polyol p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d66a242463fd47b257008557f9a8fa07
http://hdl.handle.net/10722/124488
http://hdl.handle.net/10722/124488
Publikováno v:
British Journal of Pharmacology, Vol. 156, No 8 (2009) pp. 1296-1304
BACKGROUND AND PURPOSE: Amiloride derivatives are blockers of the Na(+)/H(+) exchanger (NHE) and at micromolar concentrations have protective effects on cardiac and brain ischaemia/reperfusion injury but at higher concentrations also induce apoptosis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::eda0cf26c0e45c533b0172dbe17fb0ad
https://archive-ouverte.unige.ch/unige:20019
https://archive-ouverte.unige.ch/unige:20019